Human-relevant concentrations of the antifungal drug clotrimazole disrupts maternal and fetal steroid hormone profiles in rats

Gestational Exposure to Synthetic Steroid Hormones Impaired Sperm Quantity and Quality in Wistar Rats

(2020) Samy Ismail Ahmed et al.   International Journal of Endocrinology

Organophosphate ester flame retardants have antiandrogenic potential and affect other endocrine related endpoints in vitro and in silico

(2020) Anna Kjerstine Rosenmai et al.   CHEMOSPHERE

Estrogens and development of the rete testis, efferent ductules, epididymis and vas deferens

(2020) Rex A. Hess et al.   DIFFERENTIATION

Early pregnancy maternal progesterone administration alters pituitary and testis function and steroid profile in male fetuses

(2020) Katarzyna J. Siemienowicz et al.   Scientific Reports

A critical role for estrogen signaling in penis development

(2019) Luke C. Govers et al.   FASEB JOURNAL

A loss of estrogen signaling in the aromatase deficient mouse penis results in mild hypospadias

(2019) Samuel M. Cripps et al.   DIFFERENTIATION

The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax

(2019) Cecilie Hurup Munkboel et al.   TOXICOLOGY

In vitro and in vivo endocrine disrupting effects of the azole fungicides triticonazole and flusilazole

(2019) Monica Kam Draskau et al.   ENVIRONMENTAL POLLUTION

Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders

(2018) Camilla Lindgren Schwartz et al.   ARCHIVES OF TOXICOLOGY

Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study

(2017) Djamilla Madelung Mogensen et al.   Environmental Health

httk: R Package for High-Throughput Toxicokinetics

(2017) Robert G. Pearce et al.   Journal of Statistical Software

Environmental influences on ovarian dysgenesis — developmental windows sensitive to chemical exposures

(2017) Hanna Katarina Lilith Johansson et al.   Nature Reviews Endocrinology

Comparing effect levels of regulatory studies with endpoints derived in targeted anti-androgenic studies: example prochloraz

(2016) Stephanie Melching-Kollmuss et al.   ARCHIVES OF TOXICOLOGY

Analgesic use — prevalence, biomonitoring and endocrine and reproductive effects

(2016) David M. Kristensen et al.   Nature Reviews Endocrinology

Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility

(2016) Niels E. Skakkebaek et al.   PHYSIOLOGICAL REVIEWS

High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells

(2016) Agnes L. Karmaus et al.   TOXICOLOGICAL SCIENCES

Perfluorononanoic acid in combination with 14 chemicals exerts low-dose mixture effects in rats

(2015) Niels Hadrup et al.   ARCHIVES OF TOXICOLOGY

Timing of androgen receptor disruption and estrogen exposure underlies a spectrum of congenital penile anomalies

(2015) Zhengui Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clotrimazole as a pharmaceutical: past, present and future.

(2014) P.D. Crowley et al.   JOURNAL OF APPLIED MICROBIOLOGY

Effects of Estrogen Coadministration on Epoxiconazole Toxicity in Rats

(2013) Stefan Stinchcombe et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

In vitro - in vivo correlations for endocrine activity of a mixture of currently used pesticides

(2013) Camilla Taxvig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A pilot study of the association between genetic polymorphisms involved in estrogen signaling and infant male genital phenotypes

(2012) Sheela Sathyanarayana et al.   ASIAN JOURNAL OF ANDROLOGY

Adverse effects on sexual development in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides

(2012) Ulla Hass et al.   REPRODUCTIVE TOXICOLOGY

Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals

(2010) Mia B. Kjærstad et al.   REPRODUCTIVE TOXICOLOGY

Endocrine-disrupting properties in vivo of widely used azole fungicides

(2008) C. Taxvig et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism

(2008) Michelle Welsh et al.   JOURNAL OF CLINICAL INVESTIGATION

Recovery of suppressed male reproduction in mice exposed to progesterone during embryonic development by testosterone

(2008) C Harini et al.   REPRODUCTION