Coming of age in the frontal cortex: The role of puberty in cortical maturation

Environmental enrichment or selective activation of parvalbumin-expressing interneurons ameliorates synaptic and behavioral deficits in animal models with schizophrenia-like behaviors during adolescence

(2021) Yuhua Huang et al.   MOLECULAR PSYCHIATRY

Sex and Pubertal Status Influence Dendritic Spine Density on Frontal Corticostriatal Projection Neurons in Mice

(2020) Kristen Delevich et al.   CEREBRAL CORTEX

Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior

(2020) Lucy K. Bicks et al.   Nature Communications

Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

(2020) Ashley L. Comer et al.   PLOS BIOLOGY

Downregulation of parvalbumin expression in the prefrontal cortex during adolescence causes enduring prefrontal disinhibition in adulthood

(2020) Adriana Caballero et al.   NEUROPSYCHOPHARMACOLOGY

Dysregulated Prefrontal Cortex Inhibition in Prepubescent and Adolescent Fragile X Mouse Model

(2020) Ioannis Kramvis et al.   Frontiers in Molecular Neuroscience

Cell type–differential modulation of prefrontal cortical GABAergic interneurons on low gamma rhythm and social interaction

(2020) Ling Liu et al.   Science Advances

Influences of age and pubertal status on number and intensity of perineuronal nets in the rat medial prefrontal cortex

(2020) Carly M. Drzewiecki et al.   Brain Structure & Function

Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice

(2020) Melis Yilmaz et al.   NATURE NEUROSCIENCE

Sex differences in pubertal associations with fronto-accumbal white matter morphometry: Implications for understanding sensitivity to reward and punishment

(2020) Rajpreet Chahal et al.   NEUROIMAGE

Estrus-Cycle Regulation of Cortical Inhibition

(2019) Ann M. Clemens et al.   CURRENT BIOLOGY

Neuroscience: Sex Hormones at Work in the Neocortex

(2019) Kristen Delevich et al.   CURRENT BIOLOGY

Diminished fear extinction in adolescents is associated with an altered somatostatin interneuron-mediated inhibition in the infralimbic cortex

(2019) Peter Koppensteiner et al.   BIOLOGICAL PSYCHIATRY

Somatostatin interneurons in the prefrontal cortex control affective state discrimination in mice

(2019) Diego Scheggia et al.   NATURE NEUROSCIENCE

DCC Receptors Drive Prefrontal Cortex Maturation by Determining Dopamine Axon Targeting in Adolescence

(2018) Lauren M. Reynolds et al.   BIOLOGICAL PSYCHIATRY

Microglial Pruning of Synapses in the Prefrontal Cortex During Adolescence

(2018) Allyson P Mallya et al.   CEREBRAL CORTEX

The Bilateral Prefronto-striatal Pathway Is Necessary for Learning New Goal-Directed Actions

(2018) Genevra Hart et al.   CURRENT BIOLOGY

Specialized Subpopulations of Deep-Layer Pyramidal Neurons in the Neocortex: Bridging Cellular Properties to Functional Consequences

(2018) Arielle Baker et al.   JOURNAL OF NEUROSCIENCE

Importance of investing in adolescence from a developmental science perspective

(2018) Ronald E. Dahl et al.   NATURE

Estrogenic regulation of memory consolidation: A look beyond the hippocampus, ovaries, and females

(2018) Karyn M. Frick et al.   PHYSIOLOGY & BEHAVIOR

PV Interneurons: Critical Regulators of E/I Balance for Prefrontal Cortex-Dependent Behavior and Psychiatric Disorders

(2018) Brielle R. Ferguson et al.   Frontiers in Neural Circuits

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

(2018) Laetitia Weinhard et al.   Nature Communications

Adolescent pruning and stabilization of dendritic spines on cortical layer 5 pyramidal neurons do not depend on gonadal hormones

(2018) Josiah R. Boivin et al.   Developmental Cognitive Neuroscience

Adolescence as a neurobiological critical period for the development of higher-order cognition

(2018) Bart Larsen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Microglial dopamine receptor elimination defines sex-specific nucleus accumbens development and social behavior in adolescent rats

(2018) Ashley M. Kopec et al.   Nature Communications

Cell-Type-Specific D1 Dopamine Receptor Modulation of Projection Neurons and Interneurons in the Prefrontal Cortex

(2018) Paul G Anastasiades et al.   CEREBRAL CORTEX

Ketamine and selective activation of parvalbumin interneurons inhibit stress-induced dendritic spine elimination

(2018) Lhotse Hei Lui Ng et al.   Translational Psychiatry

Distinct Physiological Maturation of Parvalbumin-Positive Neuron Subtypes in Mouse Prefrontal Cortex

(2017) Takeaki Miyamae et al.   JOURNAL OF NEUROSCIENCE

Selective activation of parvalbumin interneurons prevents stress-induced synapse loss and perceptual defects

(2017) C-C Chen et al.   MOLECULAR PSYCHIATRY

Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican

(2017) Emilia Favuzzi et al.   NEURON

Dcc haploinsufficiency regulates dopamine receptor expression across postnatal lifespan

(2017) Matthew Pokinko et al.   NEUROSCIENCE

Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor

(2017) Charly Abi Ghanem et al.   PLoS Genetics

Inhibitory interneurons in visual cortical plasticity

(2016) Daniëlle van Versendaal et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development

(2016) Kalynn M. Schulz et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Synaptic number changes in the medial prefrontal cortex across adolescence in male and female rats: A role for pubertal onset

(2016) Carly M. Drzewiecki et al.   SYNAPSE

GABAergic Function as a Limiting Factor for Prefrontal Maturation during Adolescence

(2016) Adriana Caballero et al.   TRENDS IN NEUROSCIENCES

Long-range orbitofrontal and amygdala axons show divergent patterns of maturation in the frontal cortex across adolescence

(2016) Carolyn M. Johnson et al.   Developmental Cognitive Neuroscience

Gonadectomy before puberty increases the number of neurons and glia in the medial prefrontal cortex of female, but not male, rats

(2015) Wendy A. Koss et al.   DEVELOPMENTAL PSYCHOBIOLOGY

The Mediodorsal Thalamus Drives Feedforward Inhibition in the Anterior Cingulate Cortex via Parvalbumin Interneurons

(2015) K. Delevich et al.   JOURNAL OF NEUROSCIENCE

The neocortical circuit: themes and variations

(2015) Kenneth D Harris et al.   NATURE NEUROSCIENCE

Gamma Rhythms Link Prefrontal Interneuron Dysfunction with Cognitive Inflexibility in Dlx5/6+/− Mice

(2015) Kathleen K.A. Cho et al.   NEURON

The timing of neuronal loss across adolescence in the medial prefrontal cortex of male and female rats

(2015) J. Willing et al.   NEUROSCIENCE

Adolescent maturation of inhibitory inputs onto cingulate cortex neurons is cell-type specific and TrkB dependent

(2015) Angela Vandenberg et al.   Frontiers in Neural Circuits

Estradiol and isotype-selective estrogen receptor agonists modulate the mesocortical dopaminergic system in gonadectomized female rats

(2014) Miklós Sárvári et al.   BRAIN RESEARCH

Activation of Prefrontal Cortical Parvalbumin Interneurons Facilitates Extinction of Reward-Seeking Behavior

(2014) D. R. Sparta et al.   JOURNAL OF NEUROSCIENCE

Phasic Dopamine Neuron Activity Elicits Unique Mesofrontal Plasticity in Adolescence

(2014) S. Mastwal et al.   JOURNAL OF NEUROSCIENCE

CB1 cannabinoid receptor stimulation during adolescence impairs the maturation of GABA function in the adult rat prefrontal cortex

(2014) D K Cass et al.   MOLECULAR PSYCHIATRY

A Starring Role for Microglia in Brain Sex Differences

(2014) Kathryn M. Lenz et al.   NEUROSCIENTIST

Differential regulation of parvalbumin and calretinin interneurons in the prefrontal cortex during adolescence

(2013) Adriana Caballero et al.   Brain Structure & Function

Adolescence as a vulnerable period to alter rodent behavior

(2013) Miriam Schneider   CELL AND TISSUE RESEARCH

Pubertal timing and the development of psychopathology in adolescence and beyond

(2013) Julia A. Graber   HORMONES AND BEHAVIOR

Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression

(2013) Julien Courtin et al.   NATURE

Corticostriatal connectivity and its role in disease

(2013) Gordon M. G. Shepherd   NATURE REVIEWS NEUROSCIENCE

GENSAT BAC Cre-Recombinase Driver Lines to Study the Functional Organization of Cerebral Cortical and Basal Ganglia Circuits

(2013) Charles R. Gerfen et al.   NEURON

Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans

(2013) S. Bianchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients

(2013) C Manitt et al.   Translational Psychiatry

Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques

(2012) X. Liu et al.   GENOME RESEARCH

Evidence for a regional specificity in the density and distribution of noradrenergic varicosities in rat cortex

(2012) Kara L. Agster et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Synaptic Activity Unmasks Dopamine D2 Receptor Modulation of a Specific Class of Layer V Pyramidal Neurons in Prefrontal Cortex

(2012) S. Gee et al.   JOURNAL OF NEUROSCIENCE

Parallel Maturation of Goal-Directed Behavior and Dopaminergic Systems during Adolescence

(2012) F. Naneix et al.   JOURNAL OF NEUROSCIENCE

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Dendritic spine pathology in schizophrenia

(2012) J.R. Glausier et al.   NEUROSCIENCE

Altered fear learning across development in both mouse and human

(2012) S. S. Pattwell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dense, Unspecific Connectivity of Neocortical Parvalbumin-Positive Interneurons: A Canonical Microcircuit for Inhibition?

(2011) A. M. Packer et al.   JOURNAL OF NEUROSCIENCE

The Netrin Receptor DCC Is Required in the Pubertal Organization of Mesocortical Dopamine Circuitry

(2011) C. Manitt et al.   JOURNAL OF NEUROSCIENCE

Extraordinary neoteny of synaptic spines in the human prefrontal cortex

(2011) Zdravko Petanjek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

White matter development in adolescence: The influence of puberty and implications for affective disorders

(2011) Cecile D. Ladouceur et al.   Developmental Cognitive Neuroscience

Gonadectomy and Hormone Replacement Affects In Vivo Basal Extracellular Dopamine Levels in the Prefrontal Cortex but Not Motor Cortex of Adult Male Rats

(2010) T. Aubele et al.   CEREBRAL CORTEX

Development of calcium-permeable AMPA receptors and their correlation with NMDA receptors in fast-spiking interneurons of rat prefrontal cortex

(2010) Huai-Xing Wang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Estradiol and ERβ agonists enhance recognition memory, and DPN, an ERβ agonist, alters brain monoamines

(2010) Luis F. Jacome et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Mapping gray matter development: Implications for typical development and vulnerability to psychopathology

(2009) Nitin Gogtay et al.   BRAIN AND COGNITION

Transcriptional neoteny in the human brain

(2009) M. Somel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Analysis of the Expression of Dopamine D1 and D2 Receptors in Pyramidal and GABAergic Neurons of the Rat Prefrontal Cortex

(2008) N. Santana et al.   CEREBRAL CORTEX

Steroid hormone receptor expression and function in microglia

(2008) Amanda Sierra et al.   GLIA

A specialized NMDA receptor function in layer 5 recurrent microcircuitry of the adult rat prefrontal cortex

(2008) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pubertal ovarian hormone exposure reduces the number of myelinated axons in the splenium of the rat corpus callosum

(2007) M.A. Yates et al.   EXPERIMENTAL NEUROLOGY

An alternate pathway for androgen regulation of brain function: Activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5α-androstane-3β,17β-diol

(2007) Robert J. Handa et al.   HORMONES AND BEHAVIOR