Interferon regulatory factor 4 controls effector functions of CD8+ memory T cells

c-Jun overexpression in CAR T cells induces exhaustion resistance

(2019) Rachel C. Lynn et al.   NATURE

Differential requirements for IRF4 in the clonal expansion and homeostatic proliferation of naive and memory murine CD8+ T cells

(2018) Mana Miyakoda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells

(2018) Björn Rissiek et al.   Frontiers in Immunology

Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

(2017) Kevin Man et al.   IMMUNITY

The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate

(2017) Veena Krishnamoorthy et al.   IMMUNITY

TLR-Mediated Innate Production of IFN-γ by CD8+T Cells Is Independent of Glycolysis

(2016) Fiamma Salerno et al.   JOURNAL OF IMMUNOLOGY

Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells

(2016) Pleun Hombrink et al.   NATURE IMMUNOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection

(2015) Ribhu Nayar et al.   PLoS One

IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

(2014) M Grusdat et al.   CELL DEATH AND DIFFERENTIATION

IRF4 at the crossroads of effector T-cell fate decision

(2014) Magdalena Huber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Graded Levels of IRF4 Regulate CD8+ T Cell Differentiation and Expansion, but Not Attrition, in Response to Acute Virus Infection

(2014) R. Nayar et al.   JOURNAL OF IMMUNOLOGY

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

Interferon Regulatory Factor 4 Sustains CD8+ T Cell Expansion and Effector Differentiation

(2013) Shuyu Yao et al.   IMMUNITY

The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

(2013) Kevin Man et al.   NATURE IMMUNOLOGY

The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells

(2013) F. Raczkowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation

(2012) R. Nayar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells

(2009) D.-M. Zhao et al.   JOURNAL OF IMMUNOLOGY

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY