On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life

A New Analysis of Archaea–Bacteria Domain Separation: Variable Phylogenetic Distance and the Tempo of Early Evolution

(2020) Sarah J Berkemer et al.   MOLECULAR BIOLOGY AND EVOLUTION

Functional Modules of the Proteostasis Network

(2019) Gopal G. Jayaraj et al.   Cold Spring Harbor Perspectives in Biology

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ribosome Cooperates with a Chaperone to Guide Multi-domain Protein Folding

(2019) Kaixian Liu et al.   MOLECULAR CELL

Molecular chaperones accelerate the evolution of their protein clients in yeast

(2019) David Alvarez-Ponce et al.   Genome Biology and Evolution

The Hsp70 chaperone network

(2019) Rina Rosenzweig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tandem domain swapping: determinants of multidomain protein misfolding

(2019) Aleix Lafita et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Plasmodium falciparum Hsp70-x chaperone assists the heat stress response of the malaria parasite

(2019) Jemma Day et al.   FASEB JOURNAL

How evolution shapes enzyme selectivity – lessons from aminoacyl‐tRNA synthetases and other amino acid utilizing enzymes

(2019) Dan S. Tawfik et al.   FEBS Journal

The New Tree of Eukaryotes

(2019) Fabien Burki et al.   TRENDS IN ECOLOGY & EVOLUTION

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System

(2018) Tania Morán Luengo et al.   MOLECULAR CELL

Function, evolution, and structure of J-domain proteins

(2018) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

Archaea and the origin of eukaryotes

(2017) Laura Eme et al.   NATURE REVIEWS MICROBIOLOGY

The HSP90 chaperone machinery

(2017) Florian H. Schopf et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hierarchical complexity and the size limits of life

(2017) Noel A. Heim et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

How Do J-Proteins Get Hsp70 to Do So Many Different Things?

(2017) Elizabeth A. Craig et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rapid and accurate in silico solubility screening of a monoclonal antibody library

(2017) Pietro Sormanni et al.   Scientific Reports

Experimental Milestones in the Discovery of Molecular Chaperones as Polypeptide Unfolding Enzymes

(2016) Andrija Finka et al.   Annual Review of Biochemistry

One step beyond a ribosome: The ancient anaerobic core

(2016) Filipa L. Sousa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints

(2016) Robert G. Smock et al.   CELL

ECOD: new developments in the evolutionary classification of domains

(2016) R. Dustin Schaeffer et al.   NUCLEIC ACIDS RESEARCH

Disordered nucleiome: Abundance of intrinsic disorder in the DNA- and RNA-binding proteins in 1121 species from Eukaryota, Bacteria and Archaea

(2016) Chen Wang et al.   PROTEOMICS

The physiology and habitat of the last universal common ancestor

(2016) Madeline C. Weiss et al.   Nature Microbiology

Protein Quality Control under Oxidative Stress Conditions

(2015) Jan-Ulrik Dahl et al.   JOURNAL OF MOLECULAR BIOLOGY

The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility

(2015) Pietro Sormanni et al.   JOURNAL OF MOLECULAR BIOLOGY

Tree of Life Reveals Clock-Like Speciation and Diversification

(2015) S. Blair Hedges et al.   MOLECULAR BIOLOGY AND EVOLUTION

Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell-lines

(2015) Mingcong Wang et al.   PROTEOMICS

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

The nature of protein folding pathways

(2014) S. Walter Englander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular chaperones and proteostasis regulation during redox imbalance

(2014) Katerina Niforou et al.   Redox Biology

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Integration of Two Ancestral Chaperone Systems into One: The Evolution of Eukaryotic Molecular Chaperones in Light of Eukaryogenesis

(2013) David Bogumil et al.   MOLECULAR BIOLOGY AND EVOLUTION

Protein Expansion Is Primarily due to Indels in Intrinsically Disordered Regions

(2013) S. Light et al.   MOLECULAR BIOLOGY AND EVOLUTION

Chaperone machines for protein folding, unfolding and disaggregation

(2013) Helen Saibil   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

(2013) R. Rosenzweig et al.   SCIENCE

Cumulative Impact of Chaperone-Mediated Folding on Genome Evolution

(2012) David Bogumil et al.   BIOCHEMISTRY

Functional analysis of Hsp70 superfamily proteins of rice (Oryza sativa)

(2012) Neelam K. Sarkar et al.   CELL STRESS & CHAPERONES

Orderly order in protein intrinsic disorder distribution: disorder in 3500 proteomes from viruses and the three domains of life

(2012) Bin Xue et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

GenBank

(2012) Dennis A. Benson et al.   NUCLEIC ACIDS RESEARCH

The Repatterning of Eukaryotic Genomes by Random Genetic Drift

(2011) Michael Lynch et al.   Annual Review of Genomics and Human Genetics

Global Functional Map of the p23 Molecular Chaperone Reveals an Extensive Cellular Network

(2011) Frank J. Echtenkamp et al.   MOLECULAR CELL

Heat shock protein 90 from Escherichia coli collaborates with the DnaK chaperone system in client protein remodeling

(2011) O. Genest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Protozoan Parasites of Humans: The Role of Molecular Chaperones in Development and Pathogenesis

(2011) Addmore Shonhai et al.   PROTEIN AND PEPTIDE LETTERS

Independent evolution of the core domain and its flanking sequences in small heat shock proteins

(2010) Thomas Kriehuber et al.   FASEB JOURNAL

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

Archaeal-like chaperonins in bacteria

(2010) S. M. Techtmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of the mutation rate

(2010) Michael Lynch   TRENDS IN GENETICS

T-REKS: identification of Tandem REpeats in sequences with a K-meanS based algorithm

(2009) Julien Jorda et al.   BIOINFORMATICS

An atlas of chaperone–protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell

(2009) Yunchen Gong et al.   Molecular Systems Biology

The evolutionary significance of ancient genome duplications

(2009) Yves Van de Peer et al.   NATURE REVIEWS GENETICS

Protein Dynamism and Evolvability

(2009) N. Tokuriki et al.   SCIENCE

Guidelines for the nomenclature of the human heat shock proteins

(2008) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

A Major Clade of Prokaryotes with Ancient Adaptations to Life on Land

(2008) F. U. Battistuzzi et al.   MOLECULAR BIOLOGY AND EVOLUTION

The evolution of cell types in animals: emerging principles from molecular studies

(2008) Detlev Arendt   NATURE REVIEWS GENETICS

Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments

(2008) Tobias Haslberger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY