The Plasmodium falciparum Hsp70-x chaperone assists the heat stress response of the malaria parasite

Efficacy and safety of methylene blue in the treatment of malaria: a systematic review

(2018) G. Lu et al.   BMC Medicine

Structural heterogeneity and dynamics in protein evolution and design

(2018) Kristoffer E Johansson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Fuzziness in Protein Interactions—A Historical Perspective

(2018) Monika Fuxreiter   JOURNAL OF MOLECULAR BIOLOGY

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial

(2018) Alassane Dicko et al.   LANCET INFECTIOUS DISEASES

Molecular Mechanism of J-Domain-Triggered ATP Hydrolysis by Hsp70 Chaperones

(2018) Roman Kityk et al.   MOLECULAR CELL

Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif

(2018) Blessing Mabate et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Repurposing drugs to target the malaria parasite unfolding protein response

(2018) Yun Chen et al.   Scientific Reports

The entropic force generated by intrinsically disordered segments tunes protein function

(2018) Nicholas D. Keul et al.   NATURE

Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

(2017) Dorothy E. Loy et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Quantitative Analysis of Human Red Blood Cell Proteome

(2017) Agata H. Bryk et al.   JOURNAL OF PROTEOME RESEARCH

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

(2017) Sarah C. Charnaud et al.   PLoS One

The Exported Chaperone PfHsp70x Is Dispensable for the Plasmodium falciparum Intraerythrocytic Life Cycle

(2017) David W. Cobb et al.   mSphere

Plasmodium Helical Interspersed Subtelomeric (PHIST) Proteins, at the Center of Host Cell Remodeling

(2016) Jan D. Warncke et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Plasmodium species: master renovators of their host cells

(2016) Tania F. de Koning-Ward et al.   NATURE REVIEWS MICROBIOLOGY

The Malarial Exported PFA0660w Is an Hsp40 Co-Chaperone of PfHsp70-x

(2016) Michael O. Daniyan et al.   PLoS One

Protein Export into Malaria Parasite–Infected Erythrocytes: Mechanisms and Functional Consequences

(2015) Natalie J. Spillman et al.   Annual Review of Biochemistry

New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition

(2015) Ziming Zhang et al.   BIOCHIMIE

Roles of Intramolecular and Intermolecular Interactions in Functional Regulation of the Hsp70 J-protein Co-Chaperone Sis1

(2015) Hyun Young Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

PockDrug-Server: a new web server for predicting pocket druggability on holo and apo proteins

(2015) Hiba Abi Hussein et al.   NUCLEIC ACIDS RESEARCH

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum

(2015) Jigang Wang et al.   Nature Communications

The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation

(2015) Kacper B Rogala et al.   eLife

Selective modulation of plasmodial Hsp70s by small molecules with antimalarial activity

(2014) Ingrid L. Cockburn et al.   BIOLOGICAL CHEMISTRY

Plasmodial Hsp40 and Hsp70 chaperones: current and future perspectives

(2014) E.-R. PESCE et al.   PARASITOLOGY

Crystal Structure of the Stress-Inducible Human Heat Shock Protein 70 Substrate-Binding Domain in Complex with Peptide Substrate

(2014) Pingfeng Zhang et al.   PLoS One

Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone

(2014) Joseph Amick et al.   PROTEIN SCIENCE

Decision making inxia2

(2013) Graeme Winter et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Malaria's deadly grip: cytoadhesion ofPlasmodium falciparum-infected erythrocytes

(2013) Joseph D. Smith et al.   CELLULAR MICROBIOLOGY

CRIMALDDI: platform technologies and novel anti-malarial drug targets

(2013) Henri Vial et al.   MALARIA JOURNAL

Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle

(2013) Zhuo Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme

(2013) Parichat Prommana et al.   PLoS One

Functional Analysis of Hsp70 Inhibitors

(2013) Rainer Schlecht et al.   PLoS One

Analogues of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, As Anti-Cancer Agents

(2013) Xiaokai Li et al.   ACS Medicinal Chemistry Letters

Plasmodium falciparum-encoded exported hsp70/hsp40 chaperone/co-chaperone complexes within the host erythrocyte

(2012) Simone Külzer et al.   CELLULAR MICROBIOLOGY

Cysteine Reactivity Distinguishes Redox Sensing by the Heat-Inducible and Constitutive Forms of Heat Shock Protein 70

(2012) Yoshinari Miyata et al.   CHEMISTRY & BIOLOGY

Allosteric Drugs: The Interaction of Antitumor Compound MKT-077 with Human Hsp70 Chaperones

(2011) Aikaterini Rousaki et al.   JOURNAL OF MOLECULAR BIOLOGY

The Threat of Artemisinin-Resistant Malaria

(2011) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Binding of a Small Molecule at a Protein–Protein Interface Regulates the Chaperone Activity of Hsp70–Hsp40

(2010) Susanne Wisén et al.   ACS Chemical Biology

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Parasite-encoded Hsp40 proteins define novel mobile structures in the cytosol of the P. falciparum-infected erythrocyte

(2010) Simone Külzer et al.   CELLULAR MICROBIOLOGY

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target

(2010) Christopher G. Evans et al.   JOURNAL OF MEDICINAL CHEMISTRY

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

New insights into the blood-stage transcriptome ofPlasmodium falciparumusing RNA-Seq

(2010) Thomas D. Otto et al.   MOLECULAR MICROBIOLOGY

Moving in and renovating: exporting proteins from Plasmodium into host erythrocytes

(2010) Daniel E. Goldberg et al.   NATURE REVIEWS MICROBIOLOGY

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Malaria's Drug Miracle in Danger

(2010) M. Enserink   SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Red Blood Cell Proteome and Interactome: An Update

(2009) Angelo D’Alessandro et al.   JOURNAL OF PROTEOME RESEARCH

Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

(2009) E. B. Bertelsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From hatching to dispatching: the multiple cellular roles of the Hsp70 molecular chaperone machinery

(2008) Eirini Meimaridou et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Safety and Efficacy of Methylene Blue Combined with Artesunate or Amodiaquine for Uncomplicated Falciparum Malaria: A Randomized Controlled Trial from Burkina Faso

(2008) Augustin Zoungrana et al.   PLoS One