Characterization of the robust humoral immune response to GSK2618960, a humanized anti-IL-7 receptor monoclonal antibody, observed in healthy subjects in a Phase 1 study

Detection of Memory B Activity Against a Therapeutic Protein in Treatment-Naïve Subjects

(2018) Karen Liao et al.   AAPS Journal

‘Quality by Design’ approach for the analysis of impurities in pharmaceutical drug products and drug substances

(2018) Amandine Dispas et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Immunoregulation by IL-7R-targeting antibody-drug conjugates: overcoming steroid-resistance in cancer and autoimmune disease

(2017) Masahiro Yasunaga et al.   Scientific Reports

Therapeutic targeting of IL-7R  signaling pathways in ALL treatment

(2016) S. D. Cramer et al.   BLOOD

Immunogenicity of Biotherapeutics: Causes and Association with Posttranslational Modifications

(2016) Anshu Kuriakose et al.   Journal of Immunology Research

Contribution of enhanced engagement of antigen presentation machinery to the clinical immunogenicity of a human interleukin (IL)-21 receptor-blocking therapeutic antibody

(2015) L. Xue et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Assessment and Reporting of the Clinical Immunogenicity of Therapeutic Proteins and Peptides—Harmonized Terminology and Tactical Recommendations

(2014) G. Shankar et al.   AAPS Journal

Perspectives of the relationship between IL-7 and autoimmune diseases

(2013) Xiao-Song Wang et al.   CLINICAL RHEUMATOLOGY

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells

(2012) C. Penaranda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-IL-7 receptor-  reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function

(2012) L.-F. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization

(2010) Jessica L. Halliley et al.   VACCINE

Appearance of peripheral blood plasma cells and memory B cells in a primary and secondary immune response in humans

(2009) G. Blanchard-Rohner et al.   BLOOD

Prediction of immunogenicity: in silico paradigms, ex vivo and in vivo correlates

(2008) A DEGROOT et al.   CURRENT OPINION IN PHARMACOLOGY

Recommendations for the validation of immunoassays used for detection of host antibodies against biotechnology products

(2008) Gopi Shankar et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Influence of Prior Influenza Vaccination on Antibody and B-Cell Responses

(2008) Sanae Sasaki et al.   PLoS One