Sulforaphane-cisplatin combination inhibits the stemness and metastatic potential of TNBCs via down regulation of sirtuins-mediated EMT signaling axis

SIRT7 depletion inhibits cell proliferation, migration, and increases drug sensitivity by activating p38MAPK in breast cancer cells

(2018) Kun-Lin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mucuna pruriens (L.) DC chemo sensitize human breast cancer cells via downregulation of prolactin-mediated JAK2/STAT5A signaling

(2018) Sonam Sinha et al.   JOURNAL OF ETHNOPHARMACOLOGY

Molecular alterations in triple-negative breast cancer—the road to new treatment strategies

(2017) Carsten Denkert et al.   LANCET

SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis

(2017) Xiaolong Tang et al.   Nature Communications

Cucurbitacin B inhibits breast cancer metastasis and angiogenesis through VEGF-mediated suppression of FAK/MMP-9 signaling axis

(2016) Sonam Sinha et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition

(2016) Raffaele Palmirotta et al.   Oxidative Medicine and Cellular Longevity

Cisplatin promotes mesenchymal-like characteristics in osteosarcoma through Snail

(2016) Shuo Fang et al.   Oncology Letters

Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells

(2016) Lian Chen et al.   Oncotarget

The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer

(2016) Wenhui Zhou et al.   Cell Reports

A phase II study of capecitabine plus cisplatin in metastatic triple-negative breast cancer patients pretreated with anthracyclines and taxanes

(2015) Qiao Li et al.   CANCER BIOLOGY & THERAPY

Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis

(2015) S. Shukla et al.   Cancer Prevention Research

Distinctive role of SIRT1 expression on tumor invasion and metastasis in breast cancer by molecular subtype

(2015) Yul Ri Chung et al.   HUMAN PATHOLOGY

Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (CBCSG006): a randomised, open-label, multicentre, phase 3 trial

(2015) Xi-Chun Hu et al.   LANCET ONCOLOGY

Drosophila Dicer-2 Cleavage Is Mediated by Helicase- and dsRNA Termini-Dependent States that Are Modulated by Loquacious-PD

(2015) Niladri K. Sinha et al.   MOLECULAR CELL

Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents

(2015) Madhusoodanan Mottamal et al.   MOLECULES

A phase I study of histone deacetylase inhibitor, pracinostat (SB939), in pediatric patients with refractory solid tumors: IND203 a trial of the NCIC IND program/C17 pediatric phase I consortium

(2013) Alexandra P. Zorzi et al.   PEDIATRIC BLOOD & CANCER

SIRT1 Suppresses the Epithelial-to-Mesenchymal Transition in Cancer Metastasis and Organ Fibrosis

(2013) Petra Simic et al.   Cell Reports

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

(2012) Alexandria M Haslehurst et al.   BMC CANCER

Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer

(2012) Himashinie V.K. Diyabalanage et al.   CANCER LETTERS

SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis

(2012) V Byles et al.   ONCOGENE

An agarose spot assay for chemotactic invasion

(2010) Helen Wiggins et al.   BIOTECHNIQUES

Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours

(2010) Helen J. Mackay et al.   EUROPEAN JOURNAL OF CANCER

Triple-negative breast cancer--current status and future directions

(2009) O. Gluz et al.   ANNALS OF ONCOLOGY

Sulforaphane protects against cisplatin-induced nephrotoxicity

(2009) Carlos Enrique Guerrero-Beltrán et al.   TOXICOLOGY LETTERS