SIRT7 depletion inhibits cell proliferation, migration, and increases drug sensitivity by activating p38MAPK in breast cancer cells

Recent advances of highly selective CDK4/6 inhibitors in breast cancer

(2017) Hanxiao Xu et al.   Journal of Hematology & Oncology

SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription

(2017) Maximilian F. Blank et al.   NUCLEIC ACIDS RESEARCH

Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer

(2017) Ming Tang et al.   Theranostics

A Review on Novel Breast Cancer Therapies: Photodynamic Therapy and Plant Derived Agent Induced Cell Death Mechanisms

(2016) Blassan Plackal Adimuriyil George et al.   Anti-Cancer Agents in Medicinal Chemistry

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

(2016) Berta N Vazquez et al.   EMBO JOURNAL

The role of mitochondrial sirtuins in health and disease

(2016) Brenna Osborne et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress

(2016) Antoine Simoneau et al.   NUCLEIC ACIDS RESEARCH

Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model

(2016) Kit I Tong et al.   Cell Death & Disease

HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

(2016) Meghna Mehta et al.   Oncotarget

Next-generation proteasome inhibitor MLN9708 sensitizes breast cancer cells to doxorubicin-induced apoptosis

(2016) Hao Wang et al.   Scientific Reports

TAK1 inhibitor NG25 enhances doxorubicin-mediated apoptosis in breast cancer cells

(2016) Zhenyu Wang et al.   Scientific Reports

Sirtuin 7 in cell proliferation, stress and disease: Rise of the Seventh Sirtuin!

(2015) Shashi Kiran et al.   CELLULAR SIGNALLING

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

(2015) Shashi Kiran et al.   EXPERIMENTAL CELL RESEARCH

The overexpression of MRP4 is related to multidrug resistance in osteosarcoma cells

(2015) Feng Lin et al.   Journal of Cancer Research and Therapeutics

Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species

(2015) C. Weidner et al.   PHYTOMEDICINE

Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a

(2015) Shun Zhang et al.   Scientific Reports

The p38 MAPK-regulated PKD1/CREB/Bcl-2 pathway contributes to selenite-induced colorectal cancer cell apoptosis in vitro and in vivo

(2014) Kaiyan Hui et al.   CANCER LETTERS

SIRT1 Positively Regulates Breast Cancer Associated Human Aromatase (CYP19A1) Expression

(2013) Kimberly R. Holloway et al.   MOLECULAR ENDOCRINOLOGY

Sorting out functions of sirtuins in cancer

(2013) M Roth et al.   ONCOGENE

p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection

(2012) Derek Wakeman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Current approaches and future directions in the treatment of HER2-positive breast cancer

(2012) Sara A. Hurvitz et al.   CANCER TREATMENT REVIEWS

Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b

(2012) Jeong Kyu Kim et al.   HEPATOLOGY

Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival

(2012) Tina M. Thornton et al.   International Journal of Biological Sciences

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

(2012) Matthew F. Barber et al.   NATURE

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Prognostic Factors Affecting the Outcome of Salvage Radiotherapy for Isolated Locoregional Recurrence After Mastectomy

(2010) Kyubo Kim et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Doxorubicin pathways

(2010) Caroline F. Thorn et al.   Pharmacogenetics and Genomics

Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells

(2010) Ying-Jung Chen et al.   TOXICON

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Deacetylation of cortactin by SIRT1 promotes cell migration

(2008) Y Zhang et al.   ONCOGENE