Review
Engineering, Manufacturing
Mamta Thakur, Ishrat Majid, Shafat Hussain, Vikas Nanda
Summary: Scientists are focusing on developing biodegradable polymers like PCL to reduce plastic pollution. PCL, with its good compatibility and miscibility, has great potential in food processing.
PACKAGING TECHNOLOGY AND SCIENCE
(2021)
Article
Materials Science, Composites
Danilo D. Siqueira, Carlos B. B. Luna, Edcleide Maria Araujo, Thercio Henrique de Carvalho Costa, Renate M. R. Wellen
Summary: Biocomposites of poly(e-caprolactone) (PCL) with macaiba fiber (MF) showed promising biodegradability and performance, with plasma-treated fibers exhibiting lower elastic modulus compared to PCL.
POLYMER COMPOSITES
(2022)
Review
Chemistry, Multidisciplinary
Ming Hui Chua, Kang Le Osmund Chin, Xian Jun Loh, Qiang Zhu, Jianwei Xu
Summary: The discovery of aggregation-induced emission (ALE) phenomenon in 2001 has led to significant advancements in materials development across various research fields. ALE-active materials have found wide applications in optoelectronics, sensing, biomedical, and stimuli-responsive systems through integration with nanoscience and nanotechnology. This review article summarizes the latest research efforts in ALE-based nanomaterials, highlighting their synthesis and nonbiomedical applications, and provides an outlook on the future of ALE-based nanostructured materials in diverse fields beyond biomedicine.
Article
Chemistry, Physical
Alena Opalkova Siskova, Katarina Mosnackova, Marta Musiol, Andrej Opalek, Maria Buckova, Piotr Rychter, Anita Eckstein Andicsova
Summary: Packaging materials made of antimicrobial poly(epsilon-caprolactone) (PCL) can reduce food waste and improve the freshness and shelf life of fruits and vegetables.
Review
Nanoscience & Nanotechnology
Ziqing Huang, Guanhui Chen, Feilong Deng, Yiming Li
Summary: Graphdiyne, a novel 2D carbon material with unique properties, has shown great potential in various fields such as catalysis, energy storage, and biomedicine.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Materials Science, Multidisciplinary
Fahad Alam, Pawan Verma, Walaa Mohammad, Jeremy Teo, K. M. Varadarajan, S. Kumar
Summary: In this study, a novel nanocomposite scaffold was developed using additive manufacturing technology, with optimized bioactivity, biodegradation, and cytocompatibility of PLA/PCL/HNT material demonstrated for potential bone replacement and regeneration applications.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Shodai Hino, Norioki Kawasaki, Naoko Yamano, Tsutomu Nakamura, Atsuyoshi Nakayama
Summary: The increasing amount of non-degradable microplastics in the oceans is a significant concern for the environment and human health. Biodegradable plastics offer a potential solution, but little is known about their degradation in marine environments. This study investigated the effect of particle size on the hydrolysis and biodegradation of compostable and biodegradable polymers in seawater.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Review
Polymer Science
Bipin Gaihre, Xifeng Liu, A. Lee Miller, Michael Yaszemski, Lichun Lu
Summary: Fumarate-based polymers like PCLF and OPF have gained significant interest in biomedical applications for their tunable mechanical properties and biodegradability. PCLF is used for scaffolds while OPF is mostly explored as a hydrogel system, showing important applications in nerve, cartilage, and bone tissue engineering as well as drug delivery. Innovations in synthesis methods and the development of nano- and micro-composites using these polymers are key areas of research in enhancing cartilage and bone tissue regeneration.
Article
Polymer Science
Andre Rangel, Tuan Ngoc Nguyen, Christophe Egles, Veronique Migonney
Summary: ACL ruptures can be career-ending for professional athletes, but the recovery process is equally painful for the general population. Combining biodegradation and bioactivity could enhance the effectiveness of artificial ligaments.
JOURNAL OF APPLIED POLYMER SCIENCE
(2021)
Article
Polymer Science
Maryam Safari, Ricardo A. Perez Camargo, Laura Ballester-Bayarri, Guoming Liu, Agurtzane Mugica, Manuela Zubitur, Dujin Wang, Alejandro J. Mueller
Summary: This study explores the possibility of blending PBS and PCL with BSxCLy copolymers and systematically studies the crystallization behavior of the blends. The results show that the PBS/BS78CL22 blend exhibits good miscibility at high PBS content, while the PCL/BS15CL85 blend still displays partial miscibility at high PCL content. The BS46CL54 copolymer can crystallize in both PBS and PCL type crystals, depending on the polymeric matrix.
Article
Chemistry, Multidisciplinary
Quinten Thijssen, Astrid Quaak, Joseph Toombs, Elly De Vlieghere, Laurens Parmentier, Hayden Taylor, Sandra Van Vlierberghe
Summary: Current biodegradable and cross-linkable polymers mainly rely on acrylate crosslinking, but their brittleness limits their applicability. In this study, photo-cross-linkable poly(e-caprolactone) networks through orthogonal thiol-ene chemistry are introduced, which show improved mechanical properties compared to acrylate cross-linked materials. The tunability of the materials is evaluated by altering the molar mass between cross-links, and their biocompatibility and volumetric printability are demonstrated. This research opens up new possibilities for bedside manufacturing of biodegradable patient-specific implants.
ADVANCED MATERIALS
(2023)
Article
Multidisciplinary Sciences
Jianpu Tang, Xuemei Jia, Qian Li, Zhen Cui, Aiqi Liang, Bin Ke, Dayong Yang, Chi Yao
Summary: In this study, a DNA-based hydrogel was developed for the specific and nondestructive separation of exosomes from complex biological media. The separated exosomes were used for breast cancer detection and the therapeutics of myocardial infarction. The DNA hydrogel showed promising potential in the classification of breast cancer patients and the repair of infarcted myocardium in rat models.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Biochemistry & Molecular Biology
Jorge L. Mejia-Mendez, Rafael Vazquez-Duhalt, Luis R. Hernandez, Eugenio Sanchez-Arreola, Horacio Bach
Summary: This review compiles recent scientific literature on virus-like particles (VLPs) with biomedical applications. It covers general information about viruses, the production and therapeutic performance of VLPs, the structural classification and functionalization methods of VLPs, and various characterization techniques for examining VLPs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Pharmacology & Pharmacy
Jiang Ouyang, Siyuan Rao, Runcong Liu, Liqiang Wang, Wei Chen, Wei Tao, Na Kong
Summary: Due to their unique physicochemical characteristics, 2D materials have attracted increasing attention in the field of biomedicine. Nanomedicines based on 2D materials have been extensively applied in various diseases, showing great potential in therapeutic and imaging applications, as well as in biological functionalization.
ADVANCED DRUG DELIVERY REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Xikuang Yao, Chao Qi, Changrui Sun, Fengwei Huo, Xiqun Jiang
Summary: Poly(ethylene glycol) (PEG) has been widely used in conjugation with diagnostic and therapeutic agents or surface decoration on nanoplatforms, known as PEGylation, to enhance diagnostic and therapeutic effects. However, studies have shown that PEG abuse can lead to severe side effects and compromise therapeutic efficacy. This review presents alternatives to PEG, including poly(N-vi-nylpyrrolidone), polyacrylamides, polybetaines, poly(2-oxazoline)s, polyesters, and polysarcosine, with their synthesis, characterization, and biomedical applications in agent conjugates, nanocarriers, hydrogels, and antifouling surface coating. The potential of these PEG alternatives in constructing efficient nanoplatforms for precise nanomedicine is highlighted.
Article
Engineering, Manufacturing
Imene Chentir, Chouaib Aribi, Ahmed Fouzi Tarchoun, Hela Kchaou, Melisa Lamri, Moncef Nasri, Djalal Trache
Summary: This study developed innovative food packaging materials by blending bovine gelatin with crude sweet orange juice pomace pectin. The addition of sweet orange juice pomace pectin improved the structural properties, antibacterial activity, and antioxidant potential of the gelatin-based packaging. The G-SOPP (50/50) film showed efficient antibacterial activity, high antioxidant potential, and delayed photooxidation of virgin olive oil.
PACKAGING TECHNOLOGY AND SCIENCE
(2024)
Article
Engineering, Manufacturing
Esther Emily Silva Freitas, Euder Reis Dias, Mara Marcia Sampaio Albuquerque, Ilka Borges Biondi, Carla Rodrigues Cardoso Branco, Renato Souza Cruz, Alexsandro Branco, Geany Peruch Camilloto
Summary: The aim of this study was to develop poly(lactic acid) (PLA)-based films with antioxidant activity by incorporating Malpighia emarginata DC pomace extract (MEPE). The results showed that MEPE exhibited good antioxidant activity and improved the antioxidant properties of the films. Despite changes in the physical properties of the films, they have potential for application as active food packaging.
PACKAGING TECHNOLOGY AND SCIENCE
(2024)
