Transient anabolic effects of synovium in early post-traumatic osteoarthritis: a novel ex vivo joint tissue co-culture system for investigating synovium-chondrocyte interactions

FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis

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Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis

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FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis

(2018) Tokio Matsuzaki et al.   Science Translational Medicine

Synovitis assessed on static and dynamic contrast-enhanced magnetic resonance imaging and its association with pain in knee osteoarthritis: A cross-sectional study

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Evolution of synovitis in osteoarthritic knees and its association with clinical features

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Synovitis and the risk of knee osteoarthritis: the MOST Study

(2016) D.T. Felson et al.   OSTEOARTHRITIS AND CARTILAGE

Recommendations from the INHAND Apoptosis/Necrosis Working Group

(2016) Susan A. Elmore et al.   TOXICOLOGIC PATHOLOGY

Animal models of osteoarthritis: classification, update, and measurement of outcomes

(2016) Emmanuel L. Kuyinu et al.   Journal of Orthopaedic Surgery and Research

Semiquantitative Imaging Biomarkers of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium

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Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

(2016) Tuhina Neogi et al.   Arthritis & Rheumatology

Biological Therapies in Osteoarthritis

(2015) Claire Wenham et al.   CURRENT PHARMACEUTICAL DESIGN

Inflammation in joint injury and post-traumatic osteoarthritis

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Stimulation of Superficial Zone Protein/Lubricin/PRG4 by Transforming Growth Factor-β in Superficial Zone Articular Chondrocytes and Modulation by Glycosaminoglycans

(2015) Araceli Cuellar et al.   TISSUE ENGINEERING PART A

Influence of age on osteoarthritis progression after anterior cruciate ligament transection in rats

(2014) María Luisa Ferrándiz et al.   EXPERIMENTAL GERONTOLOGY

Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, tumor necrosis factor-α and interleukin-6, but accentuates degradation above a strain threshold

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Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis

(2013) M. Z. C. Ruan et al.   Science Translational Medicine

Osteoarthritis: A disease of the joint as an organ

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The role of synovitis in osteoarthritis pathogenesis

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Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Early diagnosis to enable early treatment of pre-osteoarthritis

(2012) Constance R Chu et al.   ARTHRITIS RESEARCH & THERAPY

Quantitative magnetic resonance imaging evidence of synovial proliferation is associated with radiographic severity of knee osteoarthritis

(2011) Svetlana Krasnokutsky et al.   ARTHRITIS AND RHEUMATISM

Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis

(2011) Sadaf Ashraf et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritis: can anti-cytokine therapy play a role in treatment?

(2010) Ana Luisa G. Calich et al.   CLINICAL RHEUMATOLOGY

Discovery of Novel Forkhead Box O1 Inhibitors for Treating Type 2 Diabetes: Improvement of Fasting Glycemia in Diabetic db/db Mice

(2010) T. Nagashima et al.   MOLECULAR PHARMACOLOGY

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

(2010) Jérémie Sellam et al.   Nature Reviews Rheumatology

Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage

(2010) T. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Effects of TGF-β1 on alternative splicing of Superficial Zone Protein in articular cartilage cultures

(2010) G.D. DuRaine et al.   OSTEOARTHRITIS AND CARTILAGE

Differential Regulation of Proteoglycan-4 Expression by IL-1α and TGF-β1 in Rat Condylar Chondrocytes

(2010) Jie Cheng et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury

(2008) K. A. Elsaid et al.   ARTHRITIS AND RHEUMATISM

Glucosamine increases hyaluronic acid production in human osteoarthritic synovium explants

(2008) EJ Uitterlinden et al.   BMC MUSCULOSKELETAL DISORDERS

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols