Luteolin Induces Apoptosis and Autophagy in HCT116 Colon Cancer Cells via p53-Dependent Pathway

Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2‑UDP glucuronosyltransferase 1A metabolic axis activation

(2020) Qian Hao et al.   ONCOLOGY REPORTS

Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

(2019) Kyoung Ah Kang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Luteolin Shifts Oxaliplatin-Induced Cell Cycle Arrest at G0/G1 to Apoptosis in HCT116 Human Colorectal Carcinoma Cells

(2019) Chan Jang et al.   Nutrients

Systematic Review on Polyphenol Intake and Health Outcomes: Is there Sufficient Evidence to Define a Health-Promoting Polyphenol-Rich Dietary Pattern?

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Regulation of apoptosis and autophagy by luteolin in human hepatocellular cancer Hep3B cells

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Intestinal phase-II metabolism of quercetin in HT29 cells, 3D human intestinal tissues and in healthy volunteers: a qualitative comparison using LC-IMS-MS and LC-HRMS

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Beclin 1 and LC3 as predictive biomarkers for metastatic colorectal carcinoma

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A Case Series of a Luteolin Formulation (Neuroprotek®) in Children with Autism Spectrum Disorders

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Molecular targets of luteolin in cancer

(2016) Muobarak J. Tuorkey   EUROPEAN JOURNAL OF CANCER PREVENTION

Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF)

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DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX

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Colorectal cancer

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Crosstalk between apoptosis, necrosis and autophagy

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An Open-Label Pilot Study of a Formulation Containing the Anti-Inflammatory Flavonoid Luteolin and Its Effects on Behavior in Children With Autism Spectrum Disorders

(2013) Anilia Taliou et al.   CLINICAL THERAPEUTICS

Induction of endoplasmic reticulum stress-mediated apoptosis and non-canonical autophagy by luteolin in NCI-H460 lung carcinoma cells

(2013) Shin-Hyung Park et al.   FOOD AND CHEMICAL TOXICOLOGY

UDP-Glucuronosyltransferase 1A Compromises Intracellular Accumulation and Anti-Cancer Effect of Tanshinone IIA in Human Colon Cancer Cells

(2013) Miao Liu et al.   PLoS One

Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells

(2012) Do Young Lim et al.   BMC GASTROENTEROLOGY

Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells

(2012) Lien Verschooten et al.   PLoS One

AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells

(2011) Juhae Kim et al.   BRAIN RESEARCH

Anti-carcinogenic Effects of the Flavonoid Luteolin

(2011) Günter Seelinger et al.   MOLECULES

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

The relationship between fasting plasma concentrations of selected flavonoids and their ordinary dietary intake

(2009) Jie Cao et al.   BRITISH JOURNAL OF NUTRITION

Mutant p53 Gain-of-Function in Cancer

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Autophagy fights disease through cellular self-digestion

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