Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis

Antidepressive Mechanisms of Probiotics and Their Therapeutic Potential

(2020) Shin Jie Yong et al.   Frontiers in Neuroscience

IDO and Kynurenine Metabolites in Peripheral and CNS Disorders

(2020) Yi-Shu Huang et al.   Frontiers in Immunology

Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines

(2020) Masaru Tanaka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antidepressant-like effects of kynurenic acid in a modified forced swim test

(2020) Masaru Tanaka et al.   Pharmacological Reports

Tryptophan Metabolic Pathways Are Altered in Obesity and Are Associated With Systemic Inflammation

(2020) Sofia Cussotto et al.   Frontiers in Immunology

Role of Leptin in Inflammation and Vice Versa

(2020) Antonio Pérez-Pérez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analyzing the Potential Biological Determinants of Autism Spectrum Disorder: From Neuroinflammation to the Kynurenine Pathway

(2020) Rosa Savino et al.   Brain Sciences

The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases

(2020) Antonio J. López-Gambero et al.   Biomedicines

Lactobacillus plantarum DR7 alleviates stress and anxiety in adults: a randomised, double-blind, placebo-controlled study

(2019) H.X. Chong et al.   Beneficial Microbes

Gut Microbe to Brain Signaling: What Happens in Vagus…

(2019) Christine Fülling et al.   NEURON

Bifidobacterium longum 1714™ Strain Modulates Brain Activity of Healthy Volunteers During Social Stress

(2019) Huiying Wang et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials

(2019) Richard T. Liu et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Microbiota-Gut-Brain Axis: New Therapeutic Opportunities

(2019) Caitríona Long-Smith et al.   Annual Review of Pharmacology and Toxicology

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau

(2019) Kelly R. Jacobs et al.   NEUROBIOLOGY OF AGING

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis

(2019) Cassandra Elise Gheorghe et al.   CURRENT OPINION IN PHARMACOLOGY

Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome

(2019) Joana S. Cruz-Pereira et al.   Annual Review of Psychology

A randomized controlled trial on the efficacy of resistant dextrin, as functional food, in women with type 2 diabetes: Targeting the hypothalamic–pituitary–adrenal axis and immune system

(2018) Mahdieh Abbasalizad Farhangi et al.   CLINICAL NUTRITION

Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial

(2018) Asma Kazemi et al.   CLINICAL NUTRITION

Neuroinflammation and the Immune-Kynurenine Pathway in Anxiety Disorders

(2018) Yong-Ku Kim et al.   Current Neuropharmacology

Acute and chronic effects of exercise on the kynurenine pathway in humans – A brief review and future perspectives

(2018) Alan J. Metcalfe et al.   PHYSIOLOGY & BEHAVIOR

Probiotic Supplementation in Patients with Alzheimer’s Dementia – An Explorative Intervention Study

(2018) Friedrich Leblhuber et al.   Current Alzheimer Research

Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study

(2018) Leszek Rudzki et al.   PSYCHONEUROENDOCRINOLOGY

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

(2017) Glenn R. Gibson et al.   Nature Reviews Gastroenterology & Hepatology

The kynurenine pathway: Towards metabolic equilibrium

(2017) Gerard Clarke et al.   NEUROPHARMACOLOGY

Kynurenine pathway metabolism and the microbiota-gut-brain axis

(2017) P.J. Kennedy et al.   NEUROPHARMACOLOGY

Kynurenine pathway metabolites and enzymes involved in redox reactions

(2017) D. González Esquivel et al.   NEUROPHARMACOLOGY

Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders

(2017) Katherine O'Farrell et al.   NEUROPHARMACOLOGY

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases

(2017) Michael D. Lovelace et al.   NEUROPHARMACOLOGY

The role of probiotics in children with autism spectrum disorder: A prospective, open-label study

(2017) Sanaa Y. Shaaban et al.   NUTRITIONAL NEUROSCIENCE

Kynurenine pathway metabolomics predicts and provides mechanistic insight into multiple sclerosis progression

(2017) Chai K. Lim et al.   Scientific Reports

Microbiota alteration is associated with the development of stress-induced despair behavior

(2017) Ioana A. Marin et al.   Scientific Reports

The Kynurenine Pathway As a Novel Link between Allergy and the Gut Microbiome

(2017) Aaron P. Van der Leek et al.   Frontiers in Immunology

Impact of prebiotic supplementation on T-cell subsets and their related cytokines, anthropometric features and blood pressure in patients with type 2 diabetes mellitus: A randomized placebo-controlled Trial

(2016) Parvin Dehghan et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Brain Aging and Disorders of the Central Nervous System: Kynurenines and Drug Metabolism

(2016) Nóra Török et al.   CURRENT DRUG METABOLISM

Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress

(2016) A. Kato-Kataoka et al.   Beneficial Microbes

Oral Probiotic VSL#3 Prevents Autoimmune Diabetes by Modulating Microbiota and Promoting Indoleamine 2,3-Dioxygenase-Enriched Tolerogenic Intestinal Environment

(2016) Jayashree Dolpady et al.   Journal of Diabetes Research

Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers

(2016) A P Allen et al.   Translational Psychiatry

Altered kynurenine pathway metabolism in autism: Implication for immune-induced glutamatergic activity

(2015) Chai K. Lim et al.   Autism Research

Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder

(2015) Jonathan Savitz et al.   BRAIN BEHAVIOR AND IMMUNITY

Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART

(2015) Birgitte Stiksrud et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The effects of probiotics on mental health and hypothalamic–pituitary–adrenal axis: A randomized, double-blind, placebo-controlled trial in petrochemical workers

(2015) Ali Akbar Mohammadi et al.   NUTRITIONAL NEUROSCIENCE

Adding fuel to the fire: the impact of stress on the ageing brain

(2015) Jack A. Prenderville et al.   TRENDS IN NEUROSCIENCES

Antipruritic effects of the probiotic strain LKM512 in adults with atopic dermatitis

(2014) Mitsuharu Matsumoto et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

(2014) Kristin Schmidt et al.   PSYCHOPHARMACOLOGY

Tryptophan-Catabolizing Enzymes – Party of Three

(2014) Helen J. Ball et al.   Frontiers in Immunology

The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders

(2013) Trevor W Stone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats

(2013) Ricardo Valladares et al.   FASEB JOURNAL

Probiotics and clinical effects: is the number what counts?

(2013) Elisa Bertazzoni et al.   JOURNAL OF CHEMOTHERAPY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome

(2012) Gerard Clarke et al.   Frontiers in Pharmacology

The role of the kynurenine metabolism in major depression

(2011) Aye-Mu Myint et al.   JOURNAL OF NEURAL TRANSMISSION

Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)

(2011) Juliana Croitoru-Lamoury et al.   PLoS One

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression

(2009) C L Raison et al.   MOLECULAR PSYCHIATRY

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat

(2008) Lieve Desbonnet et al.   JOURNAL OF PSYCHIATRIC RESEARCH