Biological potential of bioactive metabolites derived from fungal endophytes associated with medicinal plants

Lawsozaheer, a new chromone produced by an endophytic fungus Paecilomyces variotii isolated from Lawsonia Alba Lam. inhibits the growth of Staphylococcus aureus

(2020) Zaheer Abbas et al.   NATURAL PRODUCT RESEARCH

The effect of developmental and environmental factors on secondary metabolites in medicinal plants

(2020) Yanqun Li et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Antifungal polyketide derivatives from the endophytic fungus Aplosporella javeedii

(2020) Ying Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Epigenetic manipulation of filamentous fungi for biotechnological applications: a systematic review

(2020) Marcio José Poças-Fonseca et al.   BIOTECHNOLOGY LETTERS

Transcriptomic analysis of marine endophytic fungi extract identifies highly enriched anti-fungal fractions targeting cancer pathways in HepG2 cell lines

(2020) Ethel Juliet Blessie et al.   BMC GENOMICS

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

(2020) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Oral Ibrexafungerp: an investigational agent for the treatment of vulvovaginal candidiasis

(2020) Nkechi Azie et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Identification of Rosellinia species as producers of cyclodepsipeptide PF1022 A and resurrection of the genus Dematophora as inferred from polythetic taxonomy

(2020) K. Wittstein et al.   STUDIES IN MYCOLOGY

A new depsidone derivative from mangrove endophytic fungus Aspergillus sp. GXNU-A9

(2020) Lili Hao et al.   NATURAL PRODUCT RESEARCH

Perylenequinones production induced by co-culturing Setophoma sp. and Penicillium brasilianum

(2020) Jaqueline Moraes Bazioli et al.   Phytochemistry Letters

Genome-wide association study reveals novel loci associated with body size and carcass yields in Pekin ducks

(2019) Meng-Ting Deng et al.   BMC GENOMICS

Corrigendum: Powdery Mildews Are Characterized by Contracted Carbohydrate Metabolism and Diverse Effectors to Adapt to Obligate Biotrophic Lifestyle

(2019) Peng Liang et al.   Frontiers in Microbiology

Two new compounds of Penicillium polonicum, an endophytic fungus from Camptotheca acuminata Decne

(2019) Yanzhang Wen et al.   NATURAL PRODUCT RESEARCH

GKK1032C, a new alkaloid compound from the endophytic fungus Penicillium sp. CPCC 400817 with activity against methicillin-resistant S. aureus

(2019) Xin Qi et al.   JOURNAL OF ANTIBIOTICS

A Phase 2b, Dose-Finding Study Evaluating Oral Ibrexafungerp vs Fluconazole in Vulvovaginal Candidiasis (DOVE) [24J]

(2019) Rebecca Cadet et al.   OBSTETRICS AND GYNECOLOGY

Improved laser capture microdissection (LCM)-based method for isolation of RNA, including miRNA and expression analysis in woody apple bud meristem

(2019) Swati Verma et al.   PLANTA

Improvement of Curvulamine Production by Precursors Co-addition Strategy in Liquid Culture of Marine-Derived Fungus Curvularia sp. IFB-Z10

(2019) Xing-Chen Wei et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Factors Affecting the Metabolite Productions in Endophytes: Biotechnological Approaches for Production of Metabolites

(2019) Viridiana Morales-Sanchez et al.   CURRENT MEDICINAL CHEMISTRY

Natural trypanocidal product produced by endophytic fungi through co-culturing

(2019) Jainara Santos do Nascimento et al.   FOLIA MICROBIOLOGICA

Chromones with lipoprotein oxidation inhibitory activity from an endophytic fungus Alternaria brassicae JS959 derived from Vitex rotundifolia

(2019) Jung Wha Kim et al.   JOURNAL OF ANTIBIOTICS

Ascomylactams A–C, Cytotoxic 12- or 13-Membered-Ring Macrocyclic Alkaloids Isolated from the Mangrove Endophytic Fungus Didymella sp. CYSK-4, and Structure Revisions of Phomapyrrolidones A and C

(2019) Yan Chen et al.   JOURNAL OF NATURAL PRODUCTS

Ibrexafungerp: A novel oral glucan synthase inhibitor

(2019) M R Davis et al.   MEDICAL MYCOLOGY

Bioactive secondary metabolites from new endophytic fungus Curvularia. sp isolated from Rauwolfia macrophylla

(2019) Fatma Kaaniche et al.   PLoS One

In vitro activity of ibrexafungerp, a novel glucan synthase inhibitor against Candida glabrata isolates with FKS mutations

(2019) Natalie S. Nunnally et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bioactive secondary metabolites from endophytic fungi

(2019) Elena Ancheeva et al.   CURRENT MEDICINAL CHEMISTRY

Polyketides from Alternaria alternata MT-47, an endophytic fungus isolated from Huperzia serrata

(2019) Hongyun Yang et al.   FITOTERAPIA

Sesquiterpenoids and mycotoxin swainsonine from the locoweed endophytic fungus Alternaria oxytropis

(2019) Xiangmei Tan et al.   PHYTOCHEMISTRY

Species of Cryphonectriaceae occupy an endophytic niche in the Melastomataceae and are putative latent pathogens of Eucalyptus

(2019) Ginna M. Granados et al.   EUROPEAN JOURNAL OF PLANT PATHOLOGY

Three novel chromanones with biological activities from the endophytic fungus Phomopsis CGMCC No. 5416

(2019) Zhijun Yang et al.   JOURNAL OF ANTIBIOTICS

Antitumor astins originate from the fungal endophyteCyanodermella asterisliving within the medicinal plantAster tataricus

(2019) Thomas Schafhauser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioactive Metabolites from Pathogenic and Endophytic Fungi of Forest Trees

(2018) Marco Masi et al.   CURRENT MEDICINAL CHEMISTRY

Advances, Problems, and Prospects of Genetic Transformation of Fungi

(2018) N. L. Poyedinok et al.   Cytology and Genetics

Biologically active fungal depsidones: Chemistry, biosynthesis, structural characterization, and bioactivities

(2018) Sabrin R.M. Ibrahim et al.   FITOTERAPIA

Characterization, culture medium optimization and antioxidant activity of an endophytic vitexin-producing fungus Dichotomopilus funicola Y3 from pigeon pea [Cajanus cajan (L.) Millsp.]

(2018) C.B. Gu et al.   JOURNAL OF APPLIED MICROBIOLOGY

Highly diverse endophytes in roots of Cycas bifida (Cycadaceae), an ancient but endangered gymnosperm

(2018) Ying Zheng et al.   JOURNAL OF MICROBIOLOGY

Diversity of biologically active secondary metabolites from endophytic and saprotrophic fungi of the ascomycete order Xylariales

(2018) Soleiman E. Helaly et al.   NATURAL PRODUCT REPORTS

Luminescence Properties of Self-Aggregating TbIII-DOTA-Functionalized Calix[4]arenes

(2018) Florian Mayer et al.   Frontiers in Chemistry

Endophytic fungus Paecilomyces formosus LHL10 produces sester-terpenoid YW3548 and cyclic peptide that inhibit urease and α-glucosidase enzyme activities

(2018) Saqib Bilal et al.   ARCHIVES OF MICROBIOLOGY

Biosynthetic pathway and optimal conditions for the production of indole-3-acetic acid by an endophytic fungus, Colletotrichum fructicola CMU-A109

(2018) Tosapon Numponsak et al.   PLoS One

Diversity and Characterization of Endophytic Fungi Isolated From the Tropical Mangrove Species, Rhizophora mucronata, and Identification of Potential Antagonists Against the Soil-Borne Fungus, Fusarium solani

(2018) Tuan Noraida Tuan Hamzah et al.   Frontiers in Microbiology

Asperimides A–D, anti-inflammatory aromatic butenolides from a tropical endophytic fungus Aspergillus terreus

(2018) Guangfeng Liao et al.   FITOTERAPIA

Cytotoxic polyketides from endophytic fungus Phoma bellidis harbored in Ttricyrtis maculate

(2018) Wen-Xuan Wang et al.   Phytochemistry Letters

Atrichodermones A–C, three new secondary metabolites from the solid culture of an endophytic fungal strain, Trichoderma atroviride

(2017) Peng Zhou et al.   FITOTERAPIA

The genus Diaporthe: a rich source of diverse and bioactive metabolites

(2017) Clara Chepkirui et al.   MYCOLOGICAL PROGRESS

Anti-proliferative ambuic acid derivatives from Hawaiian endophytic fungus Pestalotiopsis sp. FT172

(2017) Chun-Shun Li et al.   PHYTOCHEMISTRY

Determination and production of antimicrobial compounds by Aspergillus clavatonanicus strain MJ31, an endophytic fungus from Mirabilis jalapa L. using UPLC-ESI-MS/MS and TD-GC-MS analysis

(2017) Vineet Kumar Mishra et al.   PLoS One

Functional Characterization of Endophytic Fungal Community Associated with Oryza sativa L. and Zea mays L.

(2017) Momota Potshangbam et al.   Frontiers in Microbiology

Total Synthesis of Penicinoline E, Marinamide, Methyl Marinamide and their Antimalarial Activity

(2017) Badher Naveen et al.   ChemistrySelect

Horizontal transfer of a ß-1,6-glucanase gene from an ancestral species of fungal endophyte to a cool-season grass host

(2017) Hiroshi Shinozuka et al.   Scientific Reports

Optimization of genome shuffling for high-yield production of the antitumor deacetylmycoepoxydiene in an endophytic fungus of mangrove plants

(2016) Mingzi Wang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bioprospecting Chemical Diversity and Bioactivity in a Marine DerivedAspergillus terreus

(2016) Donovon A. Adpressa et al.   CHEMISTRY & BIODIVERSITY

Agrobacterium-mediated transformation of Fusarium proliferatum

(2016) J. Bernardi-Wenzel et al.   GENETICS AND MOLECULAR RESEARCH

Phomopsichin A–D; Four New Chromone Derivatives from Mangrove Endophytic Fungus Phomopsis sp. 33#

(2016) Meixiang Huang et al.   Marine Drugs

Ericaceous plant-fungus network in a harsh alpine-subalpine environment

(2016) H. Toju et al.   MOLECULAR ECOLOGY

Multicomponent Analysis of the Differential Induction of Secondary Metabolite Profiles in Fungal Endophytes

(2016) Víctor González-Menéndez et al.   MOLECULES

Isolation and characterization of bioactive metabolites from Xylaria psidii, an endophytic fungus of the medicinal plant Aegle marmelos and their role in mitochondrial dependent apoptosis against pancreatic cancer cells

(2016) Divya Arora et al.   PHYTOMEDICINE

Seed-borne endophytic Bacillus amyloliquefaciens RWL-1 produces gibberellins and regulates endogenous phytohormones of Oryza sativa

(2016) Raheem Shahzad et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Inducing secondary metabolite production by the endophytic fungus Chaetomium sp. through fungal–bacterial co-culture and epigenetic modification

(2016) Sergi Herve Akone et al.   TETRAHEDRON

Polyketides from the Mangrove-derived fungal endophyte Pestalotiopsis clavispora

(2016) Catalina Francis Pérez Hemphill et al.   TETRAHEDRON LETTERS

Bioactive secondary metabolites with multiple activities from a fungal endophyte

(2016) Catherine W. Bogner et al.   Microbial Biotechnology

An Efficient LCM-Based Method for Tissue Specific Expression Analysis of Genes and miRNAs

(2016) Vibhav Gautam et al.   Scientific Reports

Penicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., isolated from the Rhizosphere Soil of Panax notoginseng

(2016) Ya-Nan An et al.   Scientific Reports

Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation

(2015) Jessica C. Albright et al.   ACS Chemical Biology

Uncovering the novel characteristics of Asian honey bee, Apis cerana, by whole genome sequencing

(2015) Doori Park et al.   BMC GENOMICS

Fungal biosynthesis of the bibenzoquinone oosporein to evade insect immunity

(2015) Peng Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phomopsidone A, a novel depsidone metabolite from the mangrove endophytic fungus Phomopsis sp. A123

(2014) Wei Zhang et al.   FITOTERAPIA

Laser Assisted Microdissection, an Efficient Technique to Understand Tissue Specific Gene Expression Patterns and Functional Genomics in Plants

(2014) Vibhav Gautam et al.   MOLECULAR BIOTECHNOLOGY

Antifungal Compounds Produced by Colletotrichum gloeosporioides, an Endophytic Fungus from Michelia champaca

(2014) Vanessa Chapla et al.   MOLECULES

In vitro antioxidant activity and total phenolic content of endophytic fungi isolated from Eugenia jambolana Lam.

(2014) Manila Yadav et al.   Asian Pacific Journal of Tropical Medicine

Phylogenomics of fescue grass-derived fungal endophytes based on selected nuclear genes and the mitochondrial gene complement

(2013) Piyumi N Ekanayake et al.   BMC EVOLUTIONARY BIOLOGY

Discovery of a New Class of Immunosuppressants fromTrichothecium roseumCo-inspired by Cross-Kingdom Similarity in Innate Immunity and Pharmacophore Motif

(2013) Ai Hua Zhang et al.   Chemistry-An Asian Journal

Screening Mangrove Endophytic Fungi for Antimalarial Natural Products

(2013) Laurent Calcul et al.   Marine Drugs

Evaluation of culture media for the production of secondary metabolites in a natural products screening program

(2013) Karen M VanderMolen et al.   AMB Express

In Vitro Activity of a New Oral Glucan Synthase Inhibitor (MK-3118) Tested against Aspergillus spp. by CLSI and EUCAST Broth Microdilution Methods

(2012) M. A. Pfaller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Medium Optimization for Exopolysaccharide Production in Liquid Culture of Endophytic Fungus Berkleasmium sp. Dzf12

(2012) Peiqin Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endophytic fungi from medicinal plants: a treasure hunt for bioactive metabolites

(2012) Sanjana Kaul et al.   PHYTOCHEMISTRY REVIEWS

Hypoxylon pulicicidum sp. nov. (Ascomycota, Xylariales), a Pantropical Insecticide-Producing Endophyte

(2012) Gerald F. Bills et al.   PLoS One

Screening for differentially expressed genes in Anoectochilus roxburghii (Orchidaceae) during symbiosis with the mycorrhizal fungus Epulorhiza sp.

(2012) Biao Li et al.   Science China-Life Sciences

Genomic Analysis of the Hydrocarbon-Producing, Cellulolytic, Endophytic Fungus Ascocoryne sarcoides

(2012) Tara A. Gianoulis et al.   PLoS Genetics

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Penicinoline, a new pyrrolyl 4-quinolinone alkaloid with an unprecedented ring system from an endophytic fungus Penicillium sp.

(2010) Chang-Lun Shao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

SMURF: Genomic mapping of fungal secondary metabolite clusters

(2010) Nora Khaldi et al.   FUNGAL GENETICS AND BIOLOGY

FungiFun: A web-based application for functional categorization of fungal genes and proteins

(2010) Steffen Priebe et al.   FUNGAL GENETICS AND BIOLOGY

Bioactive metabolites produced by Chaetomium globosum, an endophytic fungus isolated from Ginkgo biloba

(2009) Jian-Chun Qin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

γ-Lactones andent-Eudesmane Sesquiterpenes from the Endophytic FungusEutypellasp. BCC 13199

(2009) Masahiko Isaka et al.   JOURNAL OF NATURAL PRODUCTS

Bioactive Metabolites from the Endophytic FungusStemphylium globuliferumIsolated fromMentha pulegium

(2009) Abdessamad Debbab et al.   JOURNAL OF NATURAL PRODUCTS

Oblongolides from the Endophytic FungusPhomopsissp. BCC 9789

(2009) Taridaporn Bunyapaiboonsri et al.   JOURNAL OF NATURAL PRODUCTS

Endophytes: An emerging tool for biological control

(2008) Paul A. Backman et al.   BIOLOGICAL CONTROL

Pestaloficiols A–E, bioactive cyclopropane derivatives from the plant endophytic fungus Pestalotiopsis fici

(2008) Ling Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Genetic engineering of filamentous fungi — Progress, obstacles and future trends

(2008) Vera Meyer   BIOTECHNOLOGY ADVANCES

Bioactive Endophytes Warrant Intensified Exploration and Conservation

(2008) Stephen A. Smith et al.   PLoS One

Metabolites from the endophytic fungus Phomopsis sp. PSU-D15

(2007) Vatcharin Rukachaisirikul et al.   PHYTOCHEMISTRY