Targeting of miR-33 ameliorates phenotypes linked to age-related macular degeneration
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Title
Targeting of miR-33 ameliorates phenotypes linked to age-related macular degeneration
Authors
Keywords
microRNA, ABCA1, cholesterol, age-related macular degeneration, inflammation, retinal pigment epithelial cells, geographic atrophy
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-03-19
DOI
10.1016/j.ymthe.2021.03.014
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Note: Only part of the references are listed.- Characterizing the Retinal Phenotype in the High-Fat Diet and Western Diet Mouse Models of Prediabetes
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- (2020) Lifeng Wang et al. CELL
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- (2019) Federica Storti et al. eLife
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- (2019) Shruti Dighe et al. BRITISH JOURNAL OF OPHTHALMOLOGY
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- (2019) Gavin W. Roddy et al. CURRENT EYE RESEARCH
- The primate model for understanding and restoring vision
- (2019) Serge Picaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Understanding AMD by analogy: systematic review of lipid-related common pathogenic mechanisms in AMD, AD, AS and GN
- (2018) Qinyuan Xu et al. Lipids in Health and Disease
- Complement factor H in AMD: Bridging genetic associations and pathobiology
- (2018) Christopher B. Toomey et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium
- (2018) Nicholas N. Lyssenko et al. JOURNAL OF LIPID RESEARCH
- Regulated efflux of photoreceptor outer segment-derived cholesterol by human RPE cells
- (2017) Federica Storti et al. EXPERIMENTAL EYE RESEARCH
- Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms in Etiology of Age-Related Macular Degeneration
- (2017) Stephen Burgess et al. OPHTHALMOLOGY
- In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques
- (2017) Glenn Yiu et al. Scientific Reports
- Retinal Pigment Epithelial Cell Apoptosis is Influenced by a Combination of Macrophages and Soluble Mediators Present in Age-Related Macular Degeneration
- (2016) Gayathri Devarajan et al. CURRENT EYE RESEARCH
- Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment
- (2016) Demetrios G. Vavvas et al. EBioMedicine
- Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis
- (2016) Jian Liu et al. Scientific Reports
- Age-related macular degeneration and the aging eye
- (2016) Alon Harris et al. Clinical Interventions in Aging
- Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration
- (2015) O. Levy et al. EMBO Molecular Medicine
- Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis
- (2015) Alexandre Wagschal et al. NATURE MEDICINE
- Therapeutic Silencing of MicroRNA-33 Inhibits the Progression of Atherosclerosis in Ldlr −/− Mice—Brief Report
- (2013) Noemi Rotllan et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration
- (2013) Abdoulaye Sene et al. Cell Metabolism
- Pharmacological Inhibition of a MicroRNA Family in Nonhuman Primates by a Seed-Targeting 8-Mer AntimiR
- (2013) V. Rottiers et al. Science Translational Medicine
- MicroRNAs in Stress Signaling and Human Disease
- (2012) Joshua T. Mendell et al. CELL
- Novel method for the rapid isolation of RPE cells specifically for RNA extraction and analysis
- (2012) Cynthia Xin-Zhao Wang et al. EXPERIMENTAL EYE RESEARCH
- MicroRNAs in metabolism and metabolic disorders
- (2012) Veerle Rottiers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanisms of Age-Related Macular Degeneration
- (2012) Jayakrishna Ambati et al. NEURON
- The oil spill in ageing Bruch membrane
- (2011) C. A. Curcio et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans
- (2011) Amy K. Walker et al. CELL
- Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration
- (2011) Yi Yu et al. HUMAN MOLECULAR GENETICS
- Evidence of association ofAPOEwith age-related macular degeneration - a pooled analysis of 15 studies
- (2011) Gareth J. McKay et al. HUMAN MUTATION
- Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
- (2011) Katey J. Rayner et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
- (2011) Katey J. Rayner et al. NATURE
- Macrophage polarization in the maculae of age-related macular degeneration: A pilot study
- (2011) Xiaoguang Cao et al. PATHOLOGY INTERNATIONAL
- Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration
- (2011) L. V. Johnson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
- (2011) A. Davalos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
- (2010) A. K. Walker et al. GENES & DEVELOPMENT
- Expression of miR-33 from anSREBP2Intron Inhibits Cholesterol Export and Fatty Acid Oxidation
- (2010) Isabelle Gerin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Serum Lipid Biomarkers and Hepatic Lipase Gene Associations with Age-Related Macular Degeneration
- (2010) Robyn Reynolds et al. OPHTHALMOLOGY
- miR-33 links SREBP-2 induction to repression of sterol transporters
- (2010) T. J. Marquart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo
- (2010) T. Horie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis
- (2010) S. H. Najafi-Shoushtari et al. SCIENCE
- MiR-33 Contributes to the Regulation of Cholesterol Homeostasis
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