Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice
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Title
Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 9, Pages 3703-3711
Publisher
Proceedings of the National Academy of Sciences
Online
2019-02-12
DOI
10.1073/pnas.1814014116
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Note: Only part of the references are listed.- Complement factor H in AMD: Bridging genetic associations and pathobiology
- (2018) Christopher B. Toomey et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Intracellular complement activation—An alarm raising mechanism?
- (2018) M.P. Reichhardt et al. SEMINARS IN IMMUNOLOGY
- Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration
- (2018) Johanna M. Colijn et al. OPHTHALMOLOGY
- Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation
- (2017) Bertrand Calippe et al. IMMUNITY
- HDL-cholesterol levels and risk of age-related macular degeneration: a multiethnic genetic study using Mendelian randomization
- (2017) Qiao Fan et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration
- (2017) Chui Ming Gemmy Cheung et al. JOURNAL OF LIPID RESEARCH
- Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms in Etiology of Age-Related Macular Degeneration
- (2017) Stephen Burgess et al. OPHTHALMOLOGY
- Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration
- (2017) Brian L. Yaspan et al. Science Translational Medicine
- Retinal pigment epithelial cell multinucleation in the aging eye - a mechanism to repair damage and maintain homoeostasis
- (2016) Mei Chen et al. AGING CELL
- Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes
- (2016) M Martin et al. CELL DEATH AND DIFFERENTIATION
- Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular Degeneration
- (2016) Cynthia Owsley et al. OPHTHALMOLOGY
- Risk factors and biomarkers of age-related macular degeneration
- (2016) Nathan G. Lambert et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Higher plasma levels of complement C3a, C4a and C5a increase the risk of subretinal fibrosis in neovascular age-related macular degeneration
- (2016) Judith Lechner et al. Immunity & Ageing
- Regression of Some High-risk Features of Age-related Macular Degeneration (AMD) in Patients Receiving Intensive Statin Treatment
- (2016) Demetrios G. Vavvas et al. EBioMedicine
- Complement factor H binding of monomeric C-reactive protein downregulates proinflammatory activity and is impaired with at risk polymorphic CFH variants
- (2016) Blanca Molins et al. Scientific Reports
- Expression of Human Complement Factor H Prevents Age-Related Macular Degeneration–Like Retina Damage and Kidney Abnormalities in Aged Cfh Knockout Mice
- (2015) Jin-Dong Ding et al. AMERICAN JOURNAL OF PATHOLOGY
- Regulation of age-related macular degeneration-like pathology by complement factor H
- (2015) Christopher B. Toomey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cross Sectional and Longitudinal Associations between Cardiovascular Risk Factors and Age Related Macular Degeneration in the EPIC-Norfolk Eye Study
- (2015) Jennifer L. Y. Yip et al. PLoS One
- Age-Related Macular Degeneration: Genetics and Biology Coming Together
- (2014) Lars G. Fritsche et al. Annual Review of Genomics and Human Genetics
- Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments
- (2014) Wenchao Zheng et al. JOURNAL OF LIPID RESEARCH
- Proof of Concept, Randomized, Placebo-Controlled Study of the Effect of Simvastatin on the Course of Age-Related Macular Degeneration
- (2014) Robyn H. Guymer et al. PLoS One
- Ten-Year Follow-up of Age-Related Macular Degeneration in the Age-Related Eye Disease Study
- (2014) Emily Y. Chew et al. JAMA Ophthalmology
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration
- (2013) Donita L. Garland et al. HUMAN MOLECULAR GENETICS
- Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
- (2013) Johanna M Seddon et al. NATURE GENETICS
- A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration
- (2013) Hannes Helgason et al. NATURE GENETICS
- Systemic Complement Inhibition with Eculizumab for Geographic Atrophy in Age-Related Macular Degeneration
- (2013) Zohar Yehoshua et al. OPHTHALMOLOGY
- HDL Proteome in Hemodialysis Patients: A Quantitative Nanoflow Liquid Chromatography-Tandem Mass Spectrometry Approach
- (2012) Alain Mangé et al. PLoS One
- Spatial Distribution of the Pathways of Cholesterol Homeostasis in Human Retina
- (2012) Wenchao Zheng et al. PLoS One
- Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids
- (2012) P. X. Shaw et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The oil spill in ageing Bruch membrane
- (2011) C. A. Curcio et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
- (2011) David Weismann et al. NATURE
- A rare penetrant mutation in CFH confers high risk of age-related macular degeneration
- (2011) Soumya Raychaudhuri et al. NATURE GENETICS
- Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
- (2011) J.-D. Ding et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic variation in complement factor H and risk of coronary heart disease: Eight new studies and a meta-analysis of around 48,000 individuals
- (2010) Reecha Sofat et al. ATHEROSCLEROSIS
- The complement system
- (2010) J. Vidya Sarma et al. CELL AND TISSUE RESEARCH
- Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina
- (2010) Simon J. Clark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heparan Sulfate, Including That in Bruch's Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-Related Macular Degeneration
- (2010) U. Kelly et al. JOURNAL OF IMMUNOLOGY
- Phosducin Regulates Transmission at thePhotoreceptor-to-ON-Bipolar Cell Synapse
- (2010) R. Herrmann et al. JOURNAL OF NEUROSCIENCE
- A human apoB100 transgenic mouse expresses human apoB100 in the RPE and develops features of early AMD
- (2009) Masashi Fujihara et al. EXPERIMENTAL EYE RESEARCH
- The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
- (2009) Don H. Anderson et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Systemic Complement Activation in Age-Related Macular Degeneration
- (2008) Hendrik P. N. Scholl et al. PLoS One
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