In Silico, In Vitro, and In Vivo Evaluation of Precipitation Inhibitors in Supersaturated Lipid-Based Formulations of Venetoclax
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
In Silico, In Vitro, and In Vivo Evaluation of Precipitation Inhibitors in Supersaturated Lipid-Based Formulations of Venetoclax
Authors
Keywords
-
Journal
MOLECULAR PHARMACEUTICS
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2021-04-23
DOI
10.1021/acs.molpharmaceut.0c00645
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Combining species specific in vitro & in silico models to predict in vivo food effect in a preclinical stage – case study of Venetoclax
- (2021) Laura J. Henze et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Supersaturated lipid-based drug delivery systems – exploring impact of lipid composition type and drug properties on supersaturability and physical stability
- (2020) Alexandra-Roxana Ilie et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems
- (2020) Caroline Alvebratt et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Exploring the Impact of Surfactant Type and Digestion: Highly Digestible Surfactants Improve Oral Bioavailability of Nilotinib
- (2020) Niklas J. Koehl et al. MOLECULAR PHARMACEUTICS
- A Novel Biphasic Lipolysis Method to Predict In Vivo Performance of Lipid Based Formulations
- (2020) Patrick J O'Dwyer et al. MOLECULAR PHARMACEUTICS
- Chase Dosing of Lipid Formulations to Enhance Oral Bioavailability of Nilotinib in Rats
- (2020) Niklas J. Koehl et al. PHARMACEUTICAL RESEARCH
- Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax
- (2020) Niklas J. Koehl et al. Pharmaceutics
- Characterization of gastrointestinal transit and luminal conditions in pigs using a telemetric motility capsule
- (2020) Laura J. Henze et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- A lipolysis-permeation setup for simultaneous study of digestion and absorption in vitro
- (2019) Janneke Keemink et al. MOLECULAR PHARMACEUTICS
- New Insights into Using Lipid Based Suspensions for ‘Brick Dust’ Molecules: Case Study of Nilotinib
- (2019) Niklas J. Koehl et al. PHARMACEUTICAL RESEARCH
- Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations
- (2019) Daniel J. Price et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- An update on polymer-lipid hybrid systems for improving oral drug delivery
- (2019) Sajedehsadat Maghrebi et al. Expert Opinion on Drug Delivery
- From Quantum Chemistry to Prediction of Drug Solubility in Glycerides
- (2019) Jochem Alsenz et al. MOLECULAR PHARMACEUTICS
- The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens
- (2018) Scheyla Daniela Siqueira Jørgensen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Transformation of Biopharmaceutical Classification System Class I and III Drugs Into Ionic Liquids and Lipophilic Salts for Enhanced Developability Using Lipid Formulations
- (2018) Hywel D. Williams et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Mechanistic Physiologically Based Pharmacokinetic Modeling of the Dissolution and Food Effect of a Biopharmaceutics Classification System IV Compound—The Venetoclax Story
- (2018) Arian Emami Riedmaier et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations - a PEARRL review
- (2018) Daniel J. Price et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation
- (2018) Estelle J.A. Suys et al. MOLECULAR PHARMACEUTICS
- Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations
- (2018) Hywel D. Williams et al. MOLECULAR PHARMACEUTICS
- Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery
- (2017) Michael Morgen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
- (2017) David A. DeGoey et al. JOURNAL OF MEDICINAL CHEMISTRY
- Computational prediction of formulation strategies for beyond-rule-of-5 compounds
- (2016) Christel A.S. Bergström et al. ADVANCED DRUG DELIVERY REVIEWS
- In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate
- (2014) Nicky Thomas et al. AAPS Journal
- Biopharmaceutical Modeling of Drug Supersaturation During Lipid-Based Formulation Digestion Considering an Absorption Sink
- (2014) Cordula Stillhart et al. PHARMACEUTICAL RESEARCH
- Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: Case studies with fenofibrate
- (2013) Brendan T. Griffin et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Drug precipitation inhibitors in supersaturable formulations
- (2013) Sen Xu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Supersaturated Self-Nanoemulsifying Drug Delivery Systems (Super-SNEDDS) Enhance the Bioavailability of the Poorly Water-Soluble Drug Simvastatin in Dogs
- (2012) Nicky Thomas et al. AAPS Journal
- Characterization of Supersaturatable Formulations for Improved Absorption of Poorly Soluble Drugs
- (2012) Ping Gao et al. AAPS Journal
- COSMOquick: A Novel Interface for Fast σ-Profile Composition and Its Application to COSMO-RS Solvent Screening Using Multiple Reference Solvents
- (2012) Christoph Loschen et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- In vitro and in vivo performance of novel supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS)
- (2012) N. Thomas et al. JOURNAL OF CONTROLLED RELEASE
- Rational Coformer or Solvent Selection for Pharmaceutical Cocrystallization or Desolvation
- (2012) Yuriy A. Abramov et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Bridging solubility between drug discovery and development
- (2011) Li Di et al. DRUG DISCOVERY TODAY
- The COSMO and COSMO-RS solvation models
- (2011) Andreas Klamt Wiley Interdisciplinary Reviews-Computational Molecular Science
- The Use of Biorelevant Dissolution Media to Forecast the In Vivo Performance of a Drug
- (2010) Sandra Klein AAPS Journal
- Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?
- (2009) Joachim Brouwers et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Dry Hybrid Lipid−Silica Microcapsules Engineered from Submicron Lipid Droplets and Nanoparticles as a Novel Delivery System for Poorly Soluble Drugs
- (2009) Spomenka Simovic et al. MOLECULAR PHARMACEUTICS
- Silica-lipid hybrid (SLH) microcapsules: A novel oral delivery system for poorly soluble drugs
- (2008) Angel Tan et al. JOURNAL OF CONTROLLED RELEASE
- Characterization and Optimization of AMG 517 Supersaturatable Self‐Emulsifying Drug Delivery System (S‐SEDDS) for Improved Oral Absorption
- (2008) Ping Gao et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhancing intestinal drug solubilisation using lipid-based delivery systems
- (2007) Christopher J.H. Porter et al. ADVANCED DRUG DELIVERY REVIEWS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now