Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer’s Disease

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

(2020) Erik C. B. Johnson et al.   NATURE MEDICINE

Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease

(2020) Lenora Higginbotham et al.   Science Advances

Quantitative proteomics reveals distinct composition of amyloid plaques in Alzheimer's disease

(2019) Feng Xiong et al.   Alzheimers & Dementia

Pineal gland dysfunction in Alzheimer’s disease: relationship with the immune-pineal axis, sleep disturbance, and neurogenesis

(2019) Juhyun Song   Molecular Neurodegeneration

ATP-sensitive potassium-channel inhibitor glibenclamide attenuates HPA axis hyperactivity, depression- and anxiety-related symptoms in a rat model of Alzheimer's disease

(2018) Mohammad Hossein Esmaeili et al.   BRAIN RESEARCH BULLETIN

GABAA receptor subunit expression changes in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus

(2018) Andrea Kwakowsky et al.   JOURNAL OF NEUROCHEMISTRY

The GABAergic System as a Therapeutic Target for Alzheimer's Disease

(2018) B Calvo-Flores Guzmán et al.   JOURNAL OF NEUROCHEMISTRY

Altered expression of glutamate transporter-1 and water channel protein aquaporin-4 in human temporal cortex with Alzheimer's disease

(2018) A. Hoshi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Proteomic Profiling of Brain and Testis Reveals the Diverse Changes in Ribosomal Proteins in fmr1 Knockout Mice

(2018) Benhong Xu et al.   NEUROSCIENCE

Presynaptic calcium channels

(2018) Sumiko Mochida   NEUROSCIENCE RESEARCH

CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer’s Disease

(2018) Yang-Ping Shentu et al.   Cell Reports

Calcium signaling in Alzheimer's disease & therapies

(2018) Benjamin Chun-Kit Tong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Towards a Better Understanding of GABAergic Remodeling in Alzheimer’s Disease

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Down-regulation of the Wnt/β-catenin signaling pathway by Cacnb4

(2017) Mohamad Rima et al.   MOLECULAR BIOLOGY OF THE CELL

The expression and activity of K V 3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice

(2017) Francesca Boscia et al.   NEUROBIOLOGY OF AGING

Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit

(2017) S.L. Angulo et al.   NEUROBIOLOGY OF DISEASE

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

(2017) Hongjun Fu et al.   NEURON

PP2A as a master regulator of the cell cycle

(2016) Nathan Wlodarchak et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice

(2016) Valérie Vingtdeux et al.   Scientific Reports

Increased Persistent Sodium Current Causes Neuronal Hyperexcitability in the Entorhinal Cortex of Fmr1 Knockout Mice

(2016) Pan-Yue Deng et al.   Cell Reports

AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo

(2016) Manon Domise et al.   Scientific Reports

Endocytic membrane trafficking and neurodegenerative disease

(2015) Andrea M. A. Schreij et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hippocampal (subfield) volume and shape in relation to cognitive performance across the adult lifespan

(2015) Aristotle N. Voineskos et al.   HUMAN BRAIN MAPPING

Current approaches to enhance glutamate transporter function and expression

(2015) Andréia C. K. Fontana   JOURNAL OF NEUROCHEMISTRY

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Tau and neurodegenerative disease: the story so far

(2015) Khalid Iqbal et al.   Nature Reviews Neurology

Relationships between default-mode network connectivity, medial temporal lobe structure, and age-related memory deficits

(2015) Andrew M. Ward et al.   NEUROBIOLOGY OF AGING

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Effect of the CALHM1 G330D and R154H Human Variants on the Control of Cytosolic Ca2+ and Aβ Levels

(2014) Valérie Vingtdeux et al.   PLoS One

Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences

(2014) Michelle Mielke et al.   Clinical Epidemiology

Nuclear life of the voltage-gated Cacnb4 subunit and its role in gene transcription regulation

(2013) Michel Ronjat et al.   Channels

CALHM1 controls the Ca2+-dependent MEK, ERK, RSK and MSK signaling cascade in neurons

(2013) U. Dreses-Werringloer et al.   JOURNAL OF CELL SCIENCE

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Glia Maturation Factor Expression in Entorhinal Cortex of Alzheimer’s Disease Brain

(2013) Ramasamy Thangavel et al.   NEUROCHEMICAL RESEARCH

Meta-analysis of amyloid-cognition relations in cognitively normal older adults

(2013) T. Hedden et al.   NEUROLOGY

Alzheimer’s disease: Pathogenesis and prevention

(2012) Heiko Braak et al.   Alzheimers & Dementia

Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

(2012) Abir Tadmouri et al.   EMBO JOURNAL

Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative

(2012) Shashwath A. Meda et al.   NEUROBIOLOGY OF AGING

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Loss of functional GABAA receptors in the Alzheimer diseased brain

(2012) A. Limon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synapses and Alzheimer's Disease

(2012) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Increasing proteome coverage with offline RP HPLC coupled to online RP nanoLC–MS

(2011) Emine Gokce et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer’s disease

(2011) Robert A. Rissman et al.   JOURNAL OF NEUROCHEMISTRY

Between promiscuity and specificity: novel roles of EF-hand calcium sensors in neuronal Ca2+ signalling

(2011) Marina Mikhaylova et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

(2011) E. D. Roberson et al.   JOURNAL OF NEUROSCIENCE

Oligodendrocyte differentiation and myelination defects in OMgp null mice

(2011) Xinhua Lee et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

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(2011) Jeremy Koppel et al.   MOLECULAR MEDICINE

Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis

(2011) Geoffrey N. Smith et al.   SCHIZOPHRENIA RESEARCH

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid  42 from Isolated Intact Nerve Terminals

(2010) S. H. Kim et al.   JOURNAL OF NEUROSCIENCE

Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network

(2010) Julie A. Harris et al.   NEURON

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

The anatomy of memory: an interactive overview of the parahippocampal–hippocampal network

(2009) N. M. van Strien et al.   NATURE REVIEWS NEUROSCIENCE

Calcium hypothesis of Alzheimer’s disease

(2009) Michael J. Berridge   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Calcium signaling and neurodegenerative diseases

(2009) Ilya Bezprozvanny   TRENDS IN MOLECULAR MEDICINE

Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+-sensor proteins

(2008) Karl-Heinz Braunewell et al.   CELL AND TISSUE RESEARCH

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

From Synapse to Nucleus: Calcium-Dependent Gene Transcription in the Control of Synapse Development and Function

(2008) Paul L. Greer et al.   NEURON

PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

(2008) J. K. Atwal et al.   SCIENCE

The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing

(2008) U. Nagalakshmi et al.   SCIENCE

Linking Cellular Mechanisms to Behavior: Entorhinal Persistent Spiking and Membrane Potential Oscillations May Underlie Path Integration, Grid Cell Firing, and Episodic Memory

(2008) Michael E. Hasselmo et al.   NEURAL PLASTICITY