Gut microbiota accelerates cisplatin-induced acute liver injury associated with robust inflammation and oxidative stress in mice

Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation

(2020) Xia Chen et al.   GUT

PICRUSt2 for prediction of metagenome functions

(2020) Gavin M. Douglas et al.   NATURE BIOTECHNOLOGY

A novel effect of Aprepitant: Protection for cisplatin-induced nephrotoxicity and hepatotoxicity

(2020) Harun Un et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The clickable activity-based probe of anti-apoptotic calenduloside E

(2019) Yu Tian et al.   PHARMACEUTICAL BIOLOGY

Drug-Induced Liver Injury — Types and Phenotypes

(2019) Jay H. Hoofnagle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of NF-κB and the oxidative stress -dependent caspase-3 apoptotic pathway by betaine supplementation attenuates hepatic injury mediated by cisplatin in rats

(2019) Hanan Hagar et al.   Pharmacological Reports

Gut Microbiota-Derived Components and Metabolites in the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD)

(2019) Yun Ji et al.   Nutrients

Advances in Toxicological Research of the Anticancer Drug Cisplatin

(2019) Luyu Qi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The gut-liver axis in liver disease: pathophysiological basis for therapy

(2019) Agustín Albillos et al.   JOURNAL OF HEPATOLOGY

Myricetin Abrogates Cisplatin-Induced Oxidative Stress, Inflammatory Response, and Goblet Cell Disintegration in Colon of Wistar Rats

(2019) Muneeb U. Rehman et al.   Plants-Basel

Activating PXR by Imperatorin Attenuates Dextran Sulphate Sodium-Induced Colitis in Mice

(2018) Meijing Liu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The side effects of platinum-based chemotherapy drugs: a review for chemists

(2018) Rabbab Oun et al.   DALTON TRANSACTIONS

Celastrol reverses palmitic acid (PA)-caused TLR4-MD2 activation-dependent insulin resistance via disrupting MD2-related cellular binding to PA

(2018) Xue Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice

(2018) Shenhai Gong et al.   JOURNAL OF HEPATOLOGY

Novel therapies for malignant pleural mesothelioma

(2018) Arnaud Scherpereel et al.   LANCET ONCOLOGY

Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse tissues

(2018) Yanyan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies

(2018) Concetta Panebianco et al.   Microbiome

Intestinal microbiota mediates the susceptibility to polymicrobial sepsis-induced liver injury by granisetron generation in mice

(2018) Shenhai Gong et al.   HEPATOLOGY

The liver-gut microbiota axis modulates hepatotoxicity of tacrine in the rat

(2017) Lian Yee Yip et al.   HEPATOLOGY

The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer

(2017) Nitai C. Hait et al.   MEDIATORS OF INFLAMMATION

Gut microbiota modulation of chemotherapy efficacy and toxicity

(2017) James L. Alexander et al.   Nature Reviews Gastroenterology & Hepatology

Curcumin: A potentially powerful tool to reverse cisplatin-induced toxicity

(2017) Ramin Rezaee et al.   PHARMACOLOGICAL RESEARCH

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

(2017) Ian D. Wilson et al.   Translational Research

Effect of Intestinal Flora on Protein Expression of Drug-Metabolizing Enzymes and Transporters in the Liver and Kidney of Germ-Free and Antibiotics-Treated Mice

(2016) Takuya Kuno et al.   MOLECULAR PHARMACEUTICS

Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice

(2016) Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures

(2016) George J. Dugbartey et al.   TOXICOLOGY

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

(2016) Claire L. Boulangé et al.   Genome Medicine

Developmental Regulation of Drug-Processing Genes in Livers of Germ-Free Mice

(2015) Felcy Pavithra Selwyn et al.   TOXICOLOGICAL SCIENCES

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

On the Discovery, Biological Effects, and Use of Cisplatin and Metallocenes in Anticancer Chemotherapy

(2012) Santiago Gómez-Ruiz et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS

Physalin F Induces Cell Apoptosis in Human Renal Carcinoma Cells by Targeting NF-kappaB and Generating Reactive Oxygen Species

(2012) Szu-Ying Wu et al.   PLoS One

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

(2011) Daniel McDonald et al.   ISME Journal

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Effect of Bicyclol on Cisplatin-Induced Hepatotoxicity in the Hepatocarcinoma 22 Tumour-Bearing Mice

(2009) Ying-Nan Yu et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Intestinal flora induces the expression of Cyp3a in the mouse liver

(2009) T. Toda et al.   XENOBIOTICA

Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity

(2008) Yolanda I. Chirino et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY