Robust and Comprehensive Targeted Metabolomics Method for Quantification of 50 Different Primary, Secondary, and Sulfated Bile Acids in Multiple Biological Species (Human, Monkey, Rabbit, Dog, and Rat) and Matrices (Plasma and Urine) Using Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS) Analysis

A Change in Bile Flow: Looking Beyond Transporter Inhibition in the Development of Drug-induced Cholestasis

(2019) Brandy Garzel et al.   CURRENT DRUG METABOLISM

Drug-Induced Liver Injury — Types and Phenotypes

(2019) Jay H. Hoofnagle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of bile acid metabolism-related signaling pathways by gut microbiota in diseases

(2019) Er-teng Jia et al.   Journal of Zhejiang University-SCIENCE B

Serum metabolome and targeted bile acid profiling reveals potential novel biomarkers for drug-induced liver injury

(2019) Zhenhua Ma et al.   MEDICINE

Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid

(2019) Jae H. Chang et al.   MOLECULAR PHARMACEUTICS

Bile acid metabolites control TH17 and Treg cell differentiation

(2019) Saiyu Hang et al.   NATURE

Differential toxic effects of bile acid mixtures in isolated mitochondria and physiologically relevant HepaRG cells

(2019) Sophie L. Penman et al.   TOXICOLOGY IN VITRO

Animal models to study bile acid metabolism

(2018) Jianing Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Models of Drug Induced Liver Injury (DILI) – Current Issues and Future Perspectives

(2018) Lucija Kuna et al.   CURRENT DRUG METABOLISM

Species differences in bile acids II. Bile acid metabolism

(2018) Rhishikesh Thakare et al.   JOURNAL OF APPLIED TOXICOLOGY

Species differences in bile acids I. Plasma and urine bile acid composition

(2018) Rhishikesh Thakare et al.   JOURNAL OF APPLIED TOXICOLOGY

Detection technologies and metabolic profiling of bile acids: a comprehensive review

(2018) Yanan Liu et al.   Lipids in Health and Disease

Definitive profiling of plasma bile acids as potential biomarkers for human liver diseases using UPLC–HRMS

(2018) Yao Shi et al.   Bioanalysis

A gut–brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus

(2018) Shunmei Liu et al.   Molecular Metabolism

Bile acid homeostasis paradigm and its connotation with cholestatic liver diseases

(2018) Tingting Yang et al.   DRUG DISCOVERY TODAY

Quantification of eicosanoids and their metabolites in biological matrices: a review

(2018) Yashpal S Chhonker et al.   Bioanalysis

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Understanding mouse bile acid formation: Is it time to unwind why mice and rats make unique bile acids?

(2016) Mats Rudling   JOURNAL OF LIPID RESEARCH

Bile Acid Profiling and Quantification in Biofluids Using Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry

(2015) Magali H. Sarafian et al.   ANALYTICAL CHEMISTRY

A biosynthetic pathway for a prominent class of microbiota-derived bile acids

(2015) A Sloan Devlin et al.   Nature Chemical Biology

Metabolic Profiling of Bile Acids in Human and Mouse Blood by LC–MS/MS in Combination with Phospholipid-Depletion Solid-Phase Extraction

(2014) Jun Han et al.   ANALYTICAL CHEMISTRY

Urinary Bile Acids as Biomarkers for Liver Diseases II. Signature Profiles in Patients

(2014) Sai Praneeth R. Bathena et al.   TOXICOLOGICAL SCIENCES

The profile of bile acids and their sulfate metabolites in human urine and serum

(2013) Sai Praneeth R. Bathena et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules

(2012) Barry R Jones et al.   Bioanalysis

Translational Biomarkers: from Preclinical to Clinical a Report of 2009 AAPS/ACCP Biomarker Workshop

(2011) Jane P. F. Bai et al.   AAPS Journal

Impaired Generation of 12-Hydroxylated Bile Acids Links Hepatic Insulin Signaling with Dyslipidemia

(2011) Rebecca A. Haeusler et al.   Cell Metabolism

Profiling Circulating and Urinary Bile Acids in Patients with Biliary Obstruction before and after Biliary Stenting

(2011) Jocelyn Trottier et al.   PLoS One

Rapid quantification of bile acids and their conjugates in serum by liquid chromatography–tandem mass spectrometry

(2009) Max Scherer et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Bile acids: analysis in biological fluids and tissues

(2009) W. J. Griffiths et al.   JOURNAL OF LIPID RESEARCH

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

Identification of Human Hepatic Cytochrome P450 Enzymes Involved in the Biotransformation of Cholic and Chenodeoxycholic Acid

(2008) A. K. Deo et al.   DRUG METABOLISM AND DISPOSITION

Fifty years of advances in bile acid synthesis and metabolism

(2008) David W. Russell   JOURNAL OF LIPID RESEARCH

Bile Acids and the Membrane Bile Acid Receptor TGR5—Connecting Nutrition and Metabolism

(2008) Charles Thomas et al.   THYROID