Copper-Catalyzed Enantioselective Difluoromethylation of Amino Acids via Difluorocarbene
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Copper-Catalyzed Enantioselective Difluoromethylation of Amino Acids via Difluorocarbene
Authors
Keywords
-
Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 143, Issue 17, Pages 6376-6381
Publisher
American Chemical Society (ACS)
Online
2021-04-27
DOI
10.1021/jacs.1c02697
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Catalytic Asymmetric Reactions with N-Metallated Azomethine Ylides
- (2020) Liang Wei et al. ACCOUNTS OF CHEMICAL RESEARCH
- Cooperative Ni/Cu‐Catalyzed Asymmetric Propargylic Alkylation of Aldimine Esters
- (2020) Lingzi Peng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Copper‐Catalyzed Deaminative Difluoromethylation
- (2020) Xiaojun Zeng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Recent Advances in Catalytic Enantioselective Synthesis of Fluorinated α‐ and β‐Amino Acids
- (2020) Xue‐Xin Zhang et al. ADVANCED SYNTHESIS & CATALYSIS
- The Generation of Difluoroketenimine and Its Application in the Synthesis of α,α-Difluoro-β-amino Amides
- (2019) Rui Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A General C-H Difluoromethylation Protocol for Carbon Acids Using TMSCF2Br
- (2019) Jinbo Hu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid
- (2019) Claudio F. Meyer et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Controllable catalytic difluorocarbene transfer enables access to diversified fluoroalkylated arenes
- (2019) Xia-Ping Fu et al. Nature Chemistry
- Difluorocarbene as a Building Block for Consecutive Bond-Forming Reactions
- (2018) Alexander D. Dilman et al. ACCOUNTS OF CHEMICAL RESEARCH
- Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
- (2018) Nicholas A. Meanwell JOURNAL OF MEDICINAL CHEMISTRY
- Difluoromethylation of (hetero)aryl chlorides with chlorodifluoromethane catalyzed by nickel
- (2018) Chang Xu et al. Nature Communications
- Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides
- (2018) Zhang Feng et al. ACCOUNTS OF CHEMICAL RESEARCH
- 2-Azaallyl Anions, 2-Azaallyl Cations, 2-Azaallyl Radicals, and Azomethine Ylides
- (2018) Shaojian Tang et al. CHEMICAL REVIEWS
- Chlorodifluoromethane-triggered formation of difluoromethylated arenes catalysed by palladium
- (2017) Zhang Feng et al. Nature Chemistry
- Radical Difluoromethylation of Thiols with (Difluoromethyl)triphenylphosphonium Bromide
- (2017) Niklas B. Heine et al. ORGANIC LETTERS
- Direct Difluoromethylation of Alcohols with an Electrophilic Difluoromethylated Sulfonium Ylide
- (2016) Jiansheng Zhu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The unique fluorine effects in organic reactions: recent facts and insights into fluoroalkylations
- (2016) Chuanfa Ni et al. CHEMICAL SOCIETY REVIEWS
- Direct Difluoromethylation of Aryl Halides via Base Metal Catalysis at Room Temperature
- (2016) Long Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Catalytic, asymmetric difluorination of alkenes to generate difluoromethylated stereocenters
- (2016) S. M. Banik et al. SCIENCE
- Visible-Light-Induced Hydrodifluoromethylation of Alkenes with a Bromodifluoromethylphosphonium Bromide
- (2015) Qing-Yu Lin et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Reaction of Diazo Compounds with Difluorocarbene: An Efficient Approach towards 1,1-Difluoroolefins
- (2015) Zhikun Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylation
- (2015) Xiao-Yun Deng et al. CHEMICAL COMMUNICATIONS
- Recent Advances in Difluoromethylation Reaction
- (2015) Yang Lu et al. CURRENT ORGANIC CHEMISTRY
- Applications of Fluorine in Medicinal Chemistry
- (2015) Eric P. Gillis et al. JOURNAL OF MEDICINAL CHEMISTRY
- gem-Difluoroolefination of Diazo Compounds with TMSCF3 or TMSCF2Br: Transition-Metal-Free Cross-Coupling of Two Carbene Precursors
- (2015) Mingyou Hu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- S-((Phenylsulfonyl)difluoromethyl)thiophenium Salts: Carbon-Selective Electrophilic Difluoromethylation of β-Ketoesters, β-Diketones, and Dicyanoalkylidenes
- (2014) Xin Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions
- (2014) Xiaoyu Yang et al. CHEMICAL REVIEWS
- Recent Advances in the Synthetic Application of Difluorocarbene
- (2014) Jinbo Hu et al. SYNTHESIS-STUTTGART
- Cooperative dual palladium/silver catalyst for direct difluoromethylation of aryl bromides and iodides
- (2014) Yang Gu et al. Nature Communications
- Synthesis ofgem-Difluorocyclopropa(e)nes and O-, S-, N-, and P-Difluoromethylated Compounds with TMSCF2Br
- (2013) Lingchun Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Synthesis of Difluoromethyl Ethers with Difluoromethyltriflate
- (2013) Patrick S. Fier et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Introduction of Fluorine and Fluorine-Containing Functional Groups
- (2013) Theresa Liang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
- (2013) Jiang Wang et al. CHEMICAL REVIEWS
- Umpolung of Fluoroform by CF Bond Activation: Direct Difluoromethylation of Lithium Enolates
- (2012) Toshiaki Iida et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Copper-Mediated Difluoromethylation of (Hetero)aryl Iodides and β-Styryl Halides with Tributyl(difluoromethyl)stannane
- (2012) G. K. Surya Prakash et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- State of the Art in African Trypanosome Drug Discovery
- (2011) Robert T. Jacobs et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- The Significance of Chirality in Drug Design and Development
- (2011) W. H. Brooks et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Binding of α,α-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
- (2011) Monica Ilies et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
- (2011) Nicholas A. Meanwell JOURNAL OF MEDICINAL CHEMISTRY
- Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates
- (2010) Jing Nie et al. CHEMICAL REVIEWS
- Nonlinear Effects in Asymmetric Catalysis
- (2009) Tummanapalli Satyanarayana et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Selective difluoromethylation and monofluoromethylation reactions
- (2009) Jinbo Hu et al. CHEMICAL COMMUNICATIONS
- Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions
- (2008) Jun-An Ma et al. CHEMICAL REVIEWS
- Synthetic strategies to α-trifluoromethyl and α-difluoromethyl substituted α-amino acids
- (2008) René Smits et al. CHEMICAL SOCIETY REVIEWS
- Fluorine in medicinal chemistry
- (2007) Sophie Purser et al. CHEMICAL SOCIETY REVIEWS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search