Pro-inflammatory self-reactive T cells are found within murine TCR-αβ+CD4−CD8−PD-1+cells

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

(2015) Wong Yu et al.   IMMUNITY

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

(2015) Azad Rahimpour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Contained Self-Reactive Peripheral T Cell Repertoire: Size, Diversity, and Cellular Composition

(2015) David M. Richards et al.   JOURNAL OF IMMUNOLOGY

Programmed Cell Death 1 and Helios Distinguish TCR-αβ+Double-Negative (CD4−CD8−) T Cells That Derive from Self-Reactive CD8 T Cells

(2015) Noé Rodríguez-Rodríguez et al.   JOURNAL OF IMMUNOLOGY

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

(2015) Eoin F. McKinney et al.   NATURE

Helios defines T cells being driven to tolerance in the periphery and thymus

(2014) Ellen M. Ross et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection

(2014) Alison Crawford et al.   IMMUNITY

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

Detection of self-reactive CD8+T cells with an anergic phenotype in healthy individuals

(2014) Yuka Maeda et al.   SCIENCE

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

(2013) Rangsima Reantragoon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Murine thymic selection quantified using a unique method to capture deleted T cells

(2013) G. L. Stritesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells

(2013) Bruno Martin et al.   Nature Communications

Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection

(2012) Sarah Enouz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

Endogenous antigen tunes the responsiveness of naive B cells but not T cells

(2012) Julie Zikherman et al.   NATURE

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

(2012) Jonathan P Sherlock et al.   NATURE MEDICINE

Evolving role of 2B4/CD244 in T and NK cell responses during virus infection

(2012) Stephen N. Waggoner et al.   Frontiers in Immunology

CD3+CD4−CD8− (double negative) T cells: Saviours or villains of the immune response?

(2011) Fulvio D’Acquisto et al.   BIOCHEMICAL PHARMACOLOGY

αβ T Cell Receptors that Do Not Undergo Major Histocompatibility Complex-Specific Thymic Selection Possess Antibody-like Recognition Specificities

(2011) Anastasia N. Tikhonova et al.   IMMUNITY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Helios Expression Is a Marker of T Cell Activation and Proliferation

(2011) Tatiana Akimova et al.   PLoS One

IL-23 Receptor Regulates Unconventional IL-17–Producing T Cells That Control Bacterial Infections

(2010) Lorena Riol-Blanco et al.   JOURNAL OF IMMUNOLOGY

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

Commensal Microbiota and CD8+ T Cells Shape the Formation of Invariant NKT Cells

(2010) B. Wei et al.   JOURNAL OF IMMUNOLOGY

The Role of IL-23/IL-17 Axis in Lupus Nephritis

(2009) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

Human TCR-  + CD4- CD8- T Cells Can Derive from CD8+ T Cells and Display an Inflammatory Effector Phenotype

(2009) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Complete but curtailed T-cell response to very low-affinity antigen

(2009) Dietmar Zehn et al.   NATURE