DNA Hypomethylation of the MPO Gene in Peripheral Blood Leukocytes Is Associated with Cerebral Stroke in the Acute Phase

MPO is partially associated with neutrophil deleterious effect in acute cerebral ischemia

(2020) Ilaria Maestrini et al.   NEUROLOGY

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

(2020) Joan Montaner et al.   Nature Reviews Neurology

Hollow Prussian Blue Nanozymes Drive Neuroprotection against Ischemic Stroke via Attenuating Oxidative Stress, Counteracting Inflammation, and Suppressing Cell Apoptosis

(2019) Kai Zhang et al.   NANO LETTERS

Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people

(2019) Xu Gao et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Therapeutic Role of a Cysteine Precursor, OTC, in Ischemic Stroke Is Mediated by Improved Proteostasis in Mice

(2019) Yanying Liu et al.   Translational Stroke Research

Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular disease

(2019) Alexey Polonikov et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Recognition, Intervention, and Monitoring of Neutrophils in Acute Ischemic Stroke

(2019) Chunming Tang et al.   NANO LETTERS

Biosynthesis of human myeloperoxidase

(2018) William M. Nauseef   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Myeloperoxidase promotes tube formation, triggers ERK1/2 and Akt pathways and is expressed endogenously in endothelial cells

(2018) Alia Khalil et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

MPO (Myeloperoxidase) Reduces Endothelial Glycocalyx Thickness Dependent on Its Cationic Charge

(2018) Kashish Manchanda et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Serum matrix metalloproteinase-8, tissue inhibitor of metalloproteinase and myeloperoxidase in ischemic stroke

(2018) Frederick Palm et al.   ATHEROSCLEROSIS

Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery

(2018) Peiying Li et al.   NEUROPHARMACOLOGY

Free Radical Damage in Ischemia-Reperfusion Injury: An Obstacle in Acute Ischemic Stroke after Revascularization Therapy

(2018) Ming-Shuo Sun et al.   Oxidative Medicine and Cellular Longevity

Global DNA demethylation as an epigenetic marker of human brain metastases

(2018) Anna-Maria Barciszewska   BIOSCIENCE REPORTS

Serum myeloperoxidase concentrations for outcome prediction in acute intracerebral hemorrhage

(2018) Guan-Rong Zheng et al.   CLINICA CHIMICA ACTA

Trigonelline therapy confers neuroprotection by reduced glutathione mediated myeloperoxidase expression in animal model of ischemic stroke

(2018) Kanta Pravalika et al.   LIFE SCIENCES

Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

(2017) Boda Zhou et al.   Lipids in Health and Disease

Association of Osteopontin, Neopterin, and Myeloperoxidase With Stroke Risk in Patients With Prior Stroke or Transient Ischemic Attacks

(2017) Peter Ganz et al.   STROKE

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

(2017) Michael M. Mendelson et al.   PLOS MEDICINE

Myeloperoxidase in human peripheral blood lymphocytes: Production and subcellular localization

(2016) Sabrina Sayori Okada et al.   CELLULAR IMMUNOLOGY

The impact of detoxifying and repair gene polymorphisms on oxidative stress in ischemic stroke

(2016) Gürdal Orhan et al.   NEUROLOGICAL SCIENCES

Oxidative Stress Markers and Their Dynamic Changes in Patients after Acute Ischemic Stroke

(2016) Ingrid Žitňanová et al.   Oxidative Medicine and Cellular Longevity

DNA Methylation Dynamics in Human Carotid Plaques After Cerebrovascular EventsSignificance

(2015) Silvio Zaina et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Epigenome-wide association study identifiesTXNIPgene associated with type 2 diabetes mellitus and sustained hyperglycemia

(2015) Carolina Soriano-Tárraga et al.   HUMAN MOLECULAR GENETICS

Targeting Neutrophils in Ischemic Stroke: Translational Insights from Experimental Studies

(2015) Glen C Jickling et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Gender-specific protective effect of the −463G>A polymorphism of myeloperoxidase gene against the risk of essential hypertension in Russians

(2015) Olga Bushueva et al.   Journal of the American Society of Hypertension

Organizational Update: The World Health Organization Global Status Report on Noncommunicable Diseases 2014; One More Landmark Step in the Combat Against Stroke and Vascular Disease

(2015) S. Mendis et al.   STROKE

Tobacco smoking-response genes in blood and buccal cells

(2015) Hyun-Kyung Na et al.   TOXICOLOGY LETTERS

Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells

(2014) Ana M. Gómez-Úriz et al.   HUMAN MOLECULAR GENETICS

Biological Relevance of Inflammation and Oxidative Stress in the Pathogenesis of Arterial Diseases

(2013) David P. Hajjar et al.   AMERICAN JOURNAL OF PATHOLOGY

Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

(2013) Irina V. Gorudko et al.   Biology Open

Different prognostic value of white blood cell subtypes in patients with acute cerebral infarction

(2012) Jinkwon Kim et al.   ATHEROSCLEROSIS

Genetic Variation in Glutathione S-Transferase Genes and Risk of Nonfatal Cerebral Stroke in Patients Suffering from Essential Hypertension

(2012) Alexey Polonikov et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Leukocytosis in Patients with Neurologic Deterioration after Acute Ischemic Stroke is Associated with Poor Outcomes

(2012) Andre D. Kumar et al.   Journal of Stroke & Cerebrovascular Diseases

Post-Ischemic Inflammation in the Brain

(2012) Takashi Shichita et al.   Frontiers in Immunology

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

The C718T polymorphism in the 3′-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension

(2011) Alexey V Polonikov et al.   HYPERTENSION RESEARCH

Myeloperoxidase: An Oxidative Pathway for Generating Dysfunctional High-Density Lipoprotein

(2010) Baohai Shao et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis

(2010) Dominic J. Ciavatta et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

Thioredoxin in Vascular Biology: Role in Hypertension

(2008) Talin Ebrahimian et al.   ANTIOXIDANTS & REDOX SIGNALING

Aberrant Expression of Myeloperoxidase in Astrocytes Promotes Phospholipid Oxidation and Memory Deficits in a Mouse Model of Alzheimer Disease

(2008) Richard A. Maki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Early Neutrophilia Is Associated With Volume of Ischemic Tissue in Acute Stroke

(2007) Brian H. Buck et al.   STROKE