Linkage of Lambda Interferons in Protection Against Severe COVID-19

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

COVID ‐19: lambda interferon against viral load and hyperinflammation

(2020) Evangelos Andreakos et al.   EMBO Molecular Medicine

COVID-19 and emerging viral infections: The case for interferon lambda

(2020) Ludmila Prokunina-Olsson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

(2020) Jérôme Hadjadj et al.   SCIENCE

Importance of Type I and III Interferons at Respiratory and Intestinal Barrier Surfaces

(2020) Megan L. Stanifer et al.   Frontiers in Immunology

Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin

(2019) Liang Ye et al.   NATURE IMMUNOLOGY

Shared and Distinct Functions of Type I and Type III Interferons

(2019) Helen M. Lazear et al.   IMMUNITY

IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

(2018) Jonas Klinkhammer et al.   eLife

Lambda interferons come to light: dual function cytokines mediating antiviral immunity and damage control

(2018) Evangelos Andreakos et al.   CURRENT OPINION IN IMMUNOLOGY

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

(2017) Ioanna E. Galani et al.   IMMUNITY

Interferon-λs: Front-Line Guardians of Immunity and Homeostasis in the Respiratory Tract

(2017) Evangelos Andreakos et al.   Frontiers in Immunology

IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment

(2016) Sophia Davidson et al.   EMBO Molecular Medicine

Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures

(2013) R. W. Y. Chan et al.   JOURNAL OF VIROLOGY