Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients

Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

(2014) Kaixin Zhou et al.   Lancet Diabetes & Endocrinology

Diagnosis and Classification of Diabetes Mellitus

(2013)   DIABETES CARE

The Association of Common SNPs and Haplotypes in CETP Gene with HDL Cholesterol Levels in Latvian Population

(2013) Ilze Radovica et al.   PLoS One

Proximal Tubular Secretion of Creatinine by Organic Cation Transporter OCT2 in Cancer Patients

(2012) G. Ciarimboli et al.   CLINICAL CANCER RESEARCH

Effects of saxagliptin added to sub-maximal doses of metformin compared with uptitration of metformin in type 2 diabetes: the PROMPT study

(2012) Michel P. Hermans et al.   CURRENT MEDICAL RESEARCH AND OPINION

Pharmacogenomic association between a variant inSLC47A1gene and therapeutic response to metformin in type 2 diabetes

(2012) I. Tkáč et al.   DIABETES OBESITY & METABOLISM

Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3

(2012) L Chen et al.   PHARMACOGENOMICS JOURNAL

Clinical Pharmacokinetics of Metformin

(2011) Garry G. Graham et al.   CLINICAL PHARMACOKINETICS

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Proportion of patients at HbA1c target

(2011) K. Esposito et al.   DIABETES OBESITY & METABOLISM

Identification of somatostatin receptor type 5 gene polymorphisms associated with acromegaly

(2011) Darja Ciganoka et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c

(2011) Mette M.H. Christensen et al.   Pharmacogenetics and Genomics

Ezetimibe improves glucose metabolism by ameliorating hepatic function in Japanese patients with type 2 diabetes

(2011) Shinji Ichimori et al.   Journal of Diabetes Investigation

Initial nonadherence, primary failure and therapeutic success of metformin monotherapy in clinical practice

(2010) Gregory A. Nichols et al.   CURRENT MEDICAL RESEARCH AND OPINION

The Effect of Oral Antidiabetic Agents on A1C Levels: A systematic review and meta-analysis

(2010) D. Sherifali et al.   DIABETES CARE

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

(2010) Kaixin Zhou et al.   NATURE GENETICS

Genetic loci influencing kidney function and chronic kidney disease

(2010) John C Chambers et al.   NATURE GENETICS

Impact of Metformin-Induced Gastrointestinal Symptoms on Quality of Life and Adherence in Patients with Type 2 Diabetes

(2010) Hermes Florez et al.   POSTGRADUATE MEDICINE

The Effects of Genetic Polymorphisms in the Organic Cation Transporters OCT1, OCT2, and OCT3 on the Renal Clearance of Metformin

(2009) M V Tzvetkov et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Secondary Failure of Metformin Monotherapy in Clinical Practice

(2009) J. B. Brown et al.   DIABETES CARE

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response

(2009) Matthijs L. Becker et al.   Pharmacogenetics and Genomics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Adherence in patients transferred from immediate release metformin to a sustained release formulation: a population-based study

(2008) L. A. Donnelly et al.   DIABETES OBESITY & METABOLISM

Mechanisms Underlying Saturable Intestinal Absorption of Metformin

(2008) W. R. Proctor et al.   DRUG METABOLISM AND DISPOSITION