Genome-wide CRISPR-Cas9 screening in Bombyx mori reveals the toxicological mechanisms of environmental pollutants, fluoride and cadmium

Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage

(2020) Xiaoxue Li et al.   IMMUNITY

Genome-wide CRISPR screening reveals genes essential for cell viability and resistance to abiotic and biotic stresses in Bombyx mori

(2020) Jiasong Chang et al.   GENOME RESEARCH

Long-term effects of copper exposure to agricultural soil function and microbial community structure at a controlled and experimental field site

(2020) J.L.A. Shaw et al.   ENVIRONMENTAL POLLUTION

The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy

(2020) Jimin Yuan et al.   Journal of Hematology & Oncology

Genome editing in insects: Current status and challenges

(2019) Jun Xu et al.   National Science Review

Comparative Transcriptomics Reveals the Role of the Toll-Like Receptor Signaling Pathway in Fluoride-Induced Cardiotoxicity

(2019) Xiaoyan Yan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Regulation of osteoblast behaviors via cross-talk between Hippo/YAP and MAPK signaling pathway under fluoride exposure

(2019) Wen-qing Zhu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Genome-wide CRISPR screen for Zika virus resistance in human neural cells

(2019) Yun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting mitochondrial structure sensitizes acute myeloid leukemia to Venetoclax treatment

(2019) Xufeng Chen et al.   Cancer Discovery

Programmable targeted epigenetic editing using CRISPR system in Bombyx mori

(2019) Yue Liu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG)

(2019) Huachao Huang et al.   NUCLEIC ACIDS RESEARCH

Analysis of digital gene expression profiling in the gonad of male silkworms (Bombyx mori) under fluoride stress

(2018) Wenchao Tang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The toxic effect of sodium fluoride on Spodoptera frugiperda 9 cells and differential protein analysis following NaF treatment of cells

(2018) Huan Zuo et al.   ENVIRONMENTAL POLLUTION

Genome editing in Bombyx mori : New opportunities for silkworm functional genomics and the sericulture industry

(2018) San-Yuan Ma et al.   Insect Science

The sequence specificity of UV-induced DNA damage in a systematically altered DNA sequence

(2018) Clairine V. Khoe et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Toxic effects of fluoride on organisms

(2018) Huan Zuo et al.   LIFE SCIENCES

Effects of sodium fluoride on the reproductive development of Bombyx mori

(2018) Wenchao Tang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Cadmium-mediated miR-30a-GRP78 leads to JNK-dependent autophagy in chicken kidney

(2018) Qunxiang Shi et al.   CHEMOSPHERE

A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila

(2018) Naoki Okamoto et al.   DEVELOPMENTAL CELL

Silkworm, Bombyx mori, as an alternative model organism in toxicological research

(2018) Nouara Abdelli et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells

(2018) Xueyan Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Heavy Metal and Metalloid Pollution of Soil, Water and Foods in Bangladesh: A Critical Review

(2018) M. Islam et al.   International Journal of Environmental Research and Public Health

Putative mechanisms of genotoxicity induced by fluoride: a comprehensive review

(2017) Daniel Araki Ribeiro et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

An integrated CRISPR Bombyx mori genome editing system with improved efficiency and expanded target sites

(2017) Sanyuan Ma et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure

(2017) Shanshan Zhou et al.   PLoS Genetics

Functional Toxicogenomic Assessment of Triclosan in Human HepG2 Cells Using Genome-Wide CRISPR-Cas9 Screening

(2016) Pu Xia et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library

(2016) Shiyou Zhu et al.   NATURE BIOTECHNOLOGY

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

(2015) Oren Parnas et al.   CELL

Oxidative stress and spermatogenesis suppression in the testis of cadmium-treated Bombyx mori larvae

(2015) Hongxia Yuan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Enabling functional genomics with genome engineering

(2015) Isaac B. Hilton et al.   GENOME RESEARCH

The toxicity of NaF on BmN cells and a comparative proteomics approach to identify protein expression changes in cells under NaF-stress

(2015) Liang Chen et al.   JOURNAL OF HAZARDOUS MATERIALS

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

BNIP3 Upregulation by ERK and JNK Mediates Cadmium-Induced Necrosis in Neuronal Cells

(2014) Bin Wang et al.   TOXICOLOGICAL SCIENCES

The role of ABA and MAPK signaling pathways in plant abiotic stress responses

(2013) Agyemang Danquah et al.   BIOTECHNOLOGY ADVANCES

The ABC gene family in arthropods: Comparative genomics and role in insecticide transport and resistance

(2013) Wannes Dermauw et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

(2012) L. Ouyang et al.   CELL PROLIFERATION

Removal of heavy metal ions from wastewaters: A review

(2010) Fenglian Fu et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

SP600125 suppresses Cdk1 and induces endoreplication directly from G2 phase, independent of JNK inhibition

(2010) J A Kim et al.   ONCOGENE

The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer

(2009) Hae-Young Yong et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS