Biomimetic lipid Nanocomplexes incorporating STAT3-inhibiting peptides effectively infiltrate the lung barrier and ameliorate pulmonary fibrosis

Pulmonary fibrosis secondary to COVID-19: a call to arms?

(2020) Paolo Spagnolo et al.   Lancet Respiratory Medicine

Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

(2020) Peter M George et al.   Lancet Respiratory Medicine

COVID-19 and risk of pulmonary fibrosis: the importance of planning ahead

(2020) Francesco Gentile et al.   European Journal of Preventive Cardiology

Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β

(2019) Monika Lodyga et al.   Science Signaling

Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis

(2019) David H. Kim et al.   Science Translational Medicine

Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis

(2019) Benjamin Ng et al.   Science Translational Medicine

Treatment of acute lung injury and early- and late-stage pulmonary fibrosis with combination emulsion siRNA polyplexes

(2019) Yixin Wang et al.   JOURNAL OF CONTROLLED RELEASE

Caveolin-1–derived peptide limits development of pulmonary fibrosis

(2019) Amarnath Satheesh Marudamuthu et al.   Science Translational Medicine

Nanoparticle-Assisted Transcutaneous Delivery of a Signal Transducer and Activator of Transcription 3-Inhibiting Peptide Ameliorates Psoriasis-like Skin Inflammation

(2018) Jin Yong Kim et al.   ACS Nano

Assessment of Pulmonary Edema: Principles and Practice

(2018) Sherif Assaad et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Idiopathic Pulmonary Fibrosis

(2018) David J. Lederer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Weight loss as a predictor of mortality in patients with interstitial lung disease

(2018) Janelle Pugashetti et al.   EUROPEAN RESPIRATORY JOURNAL

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

(2018) Lindsay J. Celada et al.   Science Translational Medicine

STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas

(2018) Yi-Ru Pan et al.   Nature Communications

M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis

(2018) Jiwei Hou et al.   Cell Communication and Signaling

Native nanodiscs from blood inhibit pulmonary fibrosis

(2018) Anqi Sun et al.   BIOMATERIALS

The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease

(2017) Gerald Burgstaller et al.   EUROPEAN RESPIRATORY JOURNAL

Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway

(2017) Liu-Ya Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An approach for half-life extension and activity preservation of an anti-diabetic peptide drug based on genetic fusion with an albumin-binding aptide

(2017) Daejin Kim et al.   JOURNAL OF CONTROLLED RELEASE

Transport of nanoparticles across pulmonary surfactant monolayer: a molecular dynamics study

(2017) Yan Xu et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis

(2017) Debomita Chakraborty et al.   Nature Communications

Astragaloside IV Improves Bleomycin-Induced Pulmonary Fibrosis in Rats by Attenuating Extracellular Matrix Deposition

(2017) Liu-Cheng Li et al.   Frontiers in Pharmacology

STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation

(2016) Mesias Pedroza et al.   FASEB JOURNAL

STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus

(2016) Chuanlin Ding et al.   JOURNAL OF IMMUNOLOGY

Self-assembled nanoparticles comprising aptide–SN38 conjugates for use in targeted cancer therapy

(2016) Hyungjun Kim et al.   NANOTECHNOLOGY

Pulmonary Macrophages: A New Therapeutic Pathway in Fibrosing Lung Disease?

(2016) Adam J. Byrne et al.   TRENDS IN MOLECULAR MEDICINE

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

(2016) Xiao-Ming Meng et al.   Cell Death & Disease

Effects of nanoparticles on the mechanical functioning of the lung

(2015) Davis Q. Arick et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Characterizing the structure of lipodisq nanoparticles for membrane protein spectroscopic studies

(2015) Rongfu Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis

(2015) Antoine François et al.   JOURNAL OF AUTOIMMUNITY

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Correction: Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis

(2015) Michael Donahoe et al.   PLoS One

Macrophages During the Fibrotic Process: M2 as Friend and Foe

(2015) Tarcio Teodoro Braga et al.   Frontiers in Immunology

VEGF-binding aptides and the inhibition of choroidal and retinal neovascularization

(2014) Dong Hyun Jo et al.   BIOMATERIALS

A Specific STAT3-Binding Peptide Exerts Antiproliferative Effects and Antitumor Activity by Inhibiting STAT3 Phosphorylation and Signaling

(2014) Daejin Kim et al.   CANCER RESEARCH

Nanoparticle-Mediated Pulmonary Drug Delivery: A Review

(2014) Mukta Paranjpe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis

(2014) Thanh-Thuy T. Le et al.   JOURNAL OF IMMUNOLOGY

Intratracheal Instillation Methods and the Distribution of Administered Material in the Lung of the Rat

(2014) Yasuko Hasegawa-Baba et al.   Journal of Toxicologic Pathology

Blood Urea Nitrogen/Creatinine Ratio Identifies a High-Risk but Potentially Reversible Form of Renal Dysfunction in Patients With Decompensated Heart Failure

(2013) Meredith A. Brisco et al.   Circulation-Heart Failure

Mast Cells: A Pivotal Role in Pulmonary Fibrosis

(2013) Arul Veerappan et al.   DNA AND CELL BIOLOGY

Plasma B Lymphocyte Stimulator and B Cell Differentiation in Idiopathic Pulmonary Fibrosis Patients

(2013) J. Xue et al.   JOURNAL OF IMMUNOLOGY

Neuraminidase Reprograms Lung Tissue and Potentiates Lipopolysaccharide-Induced Acute Lung Injury in Mice

(2013) C. Feng et al.   JOURNAL OF IMMUNOLOGY

Rituximab in severe, treatment-refractory interstitial lung disease

(2013) Gregory J. Keir et al.   RESPIROLOGY

HER2-specific aptide conjugated magneto-nanoclusters for potential breast cancer imaging and therapy

(2013) Jinho Park et al.   Journal of Materials Chemistry B

Bio-Inspired Design and Potential Biomedical Applications of a Novel Class of High-Affinity Peptides

(2012) Sunghyun Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis

(2012) Mark A. Barnes et al.   HEPATOLOGY

Fibronectin extra domain B-specific aptide conjugated nanoparticles for targeted cancer imaging

(2012) Jinho Park et al.   JOURNAL OF CONTROLLED RELEASE

Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis

(2011) Harold A. Chapman   Annual Review of Physiology

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

Bicelles: Lipid Nanostructured Platforms with Potential Dermal Applications

(2011) Lucyanna Barbosa-Barros et al.   Small

Does Chronic Microaspiration Cause Idiopathic Pulmonary Fibrosis?

(2010) Joyce S. Lee et al.   AMERICAN JOURNAL OF MEDICINE

Bicellar systems for in vitro percutaneous absorption of diclofenac

(2009) L. Rubio et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanoparticle interaction with model lung surfactant monolayers

(2009) R. K. Harishchandra et al.   Journal of the Royal Society Interface

The Top 10 Things Nephrologists Wish Every Primary Care Physician Knew

(2009) Neil M. Paige et al.   MAYO CLINIC PROCEEDINGS

Pulmonary fibrosis: pathogenesis, etiology and regulation

(2009) M S Wilson et al.   Mucosal Immunology

Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease

(2008) W. Ray Kim et al.   HEPATOLOGY

Liquid and surfactant delivery into pulmonary airways

(2008) David Halpern et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY