GPR30 knockdown weakens the capacity of CAF in promoting prostate cancer cell invasion via reducing macrophage infiltration and M2 polarization

Expression and Role of the G Protein-Coupled Estrogen Receptor (GPR30/GPER) in the Development and Immune Response in Female Reproductive Cancers

(2020) Christian David Hernández-Silva et al.   Frontiers in Endocrinology

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer-stimulated CAFs enhance monocyte differentiation and pro-tumoral TAM activation via IL-6 and GM-CSF secretion

(2018) Haaglim Cho et al.   CLINICAL CANCER RESEARCH

Twenty years of the G protein-coupled estrogen receptor GPER: Historical and personal perspectives

(2018) Matthias Barton et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts

(2018) Linda Ziani et al.   Frontiers in Immunology

M2 macrophages and regulatory T cells in lethal prostate cancer

(2018) Ann Erlandsson et al.   PROSTATE

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

The inflammatory microenvironment and microbiome in prostate cancer development

(2017) Karen S. Sfanos et al.   Nature Reviews Urology

Estrogen receptor signaling in prostate cancer: Implications for carcinogenesis and tumor progression

(2017) Helmut Bonkhoff   PROSTATE

Fibroblast activation in cancer: when seed fertilizes soil

(2016) Sanya-Eduarda Kuzet et al.   CELL AND TISSUE RESEARCH

GPR30 Promotes Prostate Stromal Cell Activation via Suppression of ERα Expression and Its Downstream Signaling Pathway

(2016) Bona Jia et al.   ENDOCRINOLOGY

CAFs and TAMs: maestros of the tumour microenvironment

(2016) Yoshihiro Komohara et al.   JOURNAL OF PATHOLOGY

Estrogen receptor α in cancer associated fibroblasts suppresses prostate cancer invasion via reducing CCL5, IL6 and macrophage infiltration in the tumor microenvironment

(2016) Chiuan-Ren Yeh et al.   Molecular Cancer

GPER in CAFs regulates hypoxia-driven breast cancer invasion in a CTGF-dependent manner

(2015) JUAN REN et al.   ONCOLOGY REPORTS

Targeting GPR30 with G-1: a new therapeutic target for castration-resistant prostate cancer

(2014) Hung-Ming Lam et al.   ENDOCRINE-RELATED CANCER

RUNX1 is essential for mesenchymal stem cell proliferation and myofibroblast differentiation

(2014) Woosook Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of M1 and M2 Macrophages in Prostate Cancer in relation to Extracapsular Tumor Extension and Biochemical Recurrence after Radical Prostatectomy

(2014) M. Lanciotti et al.   Biomed Research International

Estrogen receptor α in cancer-associated fibroblasts suppresses prostate cancer invasion via modulation of thrombospondin 2 and matrix metalloproteinase 3

(2013) Spencer Slavin et al.   CARCINOGENESIS

Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression

(2013) G Comito et al.   ONCOGENE

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation

(2013) Fen Li et al.   PLoS One

Cancer-associated fibroblasts and macrophages

(2013) Paola Chiarugi   OncoImmunology

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

Differential macrophage programming in the tumor microenvironment

(2012) Brian Ruffell et al.   TRENDS IN IMMUNOLOGY

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Nuclear Alternate Estrogen Receptor GPR30 Mediates 17 -Estradiol-Induced Gene Expression and Migration in Breast Cancer-Associated Fibroblasts

(2010) A. Madeo et al.   CANCER RESEARCH

Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21 and induction of G2 cell-cycle arrest

(2010) Q K Y Chan et al.   CELL DEATH AND DIFFERENTIATION

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Both nongenomic and genomic effects are involved in estradiol's enhancing the phenotype of smooth muscle cells in cultured prostate stromal cells

(2009) Zhisong Zhang et al.   PROSTATE

Low stroma androgen receptor level in normal and tumor prostate tissue is related to poor outcome in prostate cancer patients

(2009) Pernilla Wikström et al.   PROSTATE

Modulated expression of WFDC1 during carcinogenesis and cellular senescence

(2008) Shalom Madar et al.   CARCINOGENESIS

Decrease in stromal androgen receptor associates with androgen-independent disease and promotes prostate cancer cell proliferation and invasion

(2008) Yirong Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE