Piperlongumine attenuates oxidative stress, inflammatory, and apoptosis through modulating the GLUT‐2/4 and AKT signaling pathway in streptozotocin‐induced diabetic rats

Antioxidant Effects and Mechanisms of Medicinal Plants and Their Bioactive Compounds for the Prevention and Treatment of Type 2 Diabetes: An Updated Review

(2020) Jeremiah Oshiomame Unuofin et al.   Oxidative Medicine and Cellular Longevity

Definition, Klassifikation und Diagnostik des Diabetes mellitus

(2020) Astrid Petersmann et al.   Diabetologe

The mechanism(s) of action of antioxidants: From scavenging reactive oxygen/nitrogen species to redox signaling and the generation of bioactive secondary metabolites

(2019) Attila Hunyadi   MEDICINAL RESEARCH REVIEWS

Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells

(2019) Peichen Zhang et al.   CELLULAR ONCOLOGY

Co-encapsulation of dual drug loaded in MLNPs: Implication on sustained drug release and effectively inducing apoptosis in oral carcinoma cells

(2018) Sivaraj Mehnath et al.   BIOMEDICINE & PHARMACOTHERAPY

[6]-Shogaol attenuates inflammation, cell proliferation via modulate NF-κB and AP-1 oncogenic signaling in 7,12-dimethylbenz[ a ]anthracene induced oral carcinogenesis

(2018) Govindhan Annamalai et al.   BIOMEDICINE & PHARMACOTHERAPY

Guava leaf inhibits hepatic gluconeogenesis and increases glycogen synthesis via AMPK/ACC signaling pathways in streptozotocin-induced diabetic rats

(2018) Ramachandran Vinayagam et al.   BIOMEDICINE & PHARMACOTHERAPY

Allyl methyl sulfide, an organosulfur compound alleviates hyperglycemia mediated hepatic oxidative stress and inflammation in streptozotocin - induced experimental rats

(2018) Kathiroli Sujithra et al.   BIOMEDICINE & PHARMACOTHERAPY

Mechanism of Generation of Oxidative Stress and Pathophysiology of Type 2 Diabetes Mellitus: How Are They Interlinked?

(2017) Kanwal Rehman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Geraniol, a natural monoterpene, ameliorates hyperglycemia by attenuating the key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats

(2017) Sukumar Babukumar et al.   PHARMACEUTICAL BIOLOGY

Metformin ameliorates insulitis in STZ-induced diabetic mice

(2017) Guo-Jun Jiang et al.   PeerJ

[6]-Shogaol, a dietary phenolic compound, induces oxidative stress mediated mitochondrial dependant apoptosis through activation of proapoptotic factors in Hep-2 cells

(2016) Govindhan Annamalai et al.   BIOMEDICINE & PHARMACOTHERAPY

β-Caryophyllene, a natural sesquiterpene lactone attenuates hyperglycemia mediated oxidative and inflammatory stress in experimental diabetic rats

(2016) Rafeek Hidhayath Basha et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Synthesis of Piperlongumine Analogues and Discovery of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators as Potential Neuroprotective Agents

(2015) Shoujiao Peng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death

(2014) P Makhov et al.   BRITISH JOURNAL OF CANCER

Novel therapeutics for type 2 diabetes: insulin resistance

(2014) Q.-A. Altaf et al.   DIABETES OBESITY & METABOLISM

Overview of the therapeutic potential of piplartine (piperlongumine)

(2012) Daniel P. Bezerra et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians

(2011) Garima Juyal et al.   PLoS One

Pancreatic β-Cell Death in Response to Pro-Inflammatory Cytokines Is Distinct from Genuine Apoptosis

(2011) J. Jason Collier et al.   PLoS One

Insulin-feedback via PI3K-C2α activated PKBα/Akt1 is required for glucose-stimulated insulin secretion

(2010) Barbara Leibiger et al.   FASEB JOURNAL

α-Lipoic acid and ebselen prevent ischemia/reperfusion injury in the rat intestine

(2008) Ahmet Guven et al.   SURGERY TODAY