Neoline Improves Memory Impairment and Reduces Amyloid-β Level and Tau Phosphorylation Through AMPK Activation in the Mouse Alzheimer’s Disease Model

AdipoRon improves cognitive dysfunction of Alzheimer’s disease and rescues impaired neural stem cell proliferation through AdipoR1/AMPK pathway

(2020) Bin Liu et al.   EXPERIMENTAL NEUROLOGY

Upregulation of AMPK Ameliorates Alzheimer’s Disease-Like Tau Pathology and Memory Impairment

(2020) Lin Wang et al.   MOLECULAR NEUROBIOLOGY

Neoline, an active ingredient of the processed aconite root in Goshajinkigan formulation, targets Nav1.7 to ameliorate mechanical hyperalgesia in diabetic mice

(2020) Yoshihiko Nakatani et al.   JOURNAL OF ETHNOPHARMACOLOGY

AMPK Ameliorates Tau Acetylation and Memory Impairment Through Sirt1

(2020) Lin Wang et al.   MOLECULAR NEUROBIOLOGY

Neoline is the active ingredient of processed aconite root against murine peripheral neuropathic pain model, and its pharmacokinetics in rats

(2019) Yohei Tanimura et al.   JOURNAL OF ETHNOPHARMACOLOGY

Apathy and anxiety are early markers of Alzheimer's disease

(2019) Maurits Johansson et al.   NEUROBIOLOGY OF AGING

C 19 -Diterpenoid alkaloid arabinosides from an aqueous extract of the lateral root of Aconitum carmichaelii and their analgesic activities

(2018) Qinglan Guo et al.   Acta Pharmaceutica Sinica B

Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

(2018) Cyril Laurent et al.   Biomedical Journal

Anxiety as a risk factor of Alzheimer's disease and vascular dementia – ERRATUM

(2018) Eva Becker et al.   BRITISH JOURNAL OF PSYCHIATRY

AMPK activation: Role in the signaling pathways of neuroinflammation and neurodegeneration

(2017) Christina Alves Peixoto et al.   EXPERIMENTAL NEUROLOGY

Anxiety as a Predictor for Cognitive Decline and Dementia: A Systematic Review and Meta-Analysis

(2016) Bernice Gulpers et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Drug treatments in Alzheimers disease

(2016) R. Briggs et al.   CLINICAL MEDICINE

Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain

(2016) Toshiaki Suzuki et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hypothalamic AMPK: a canonical regulator of whole-body energy balance

(2016) Miguel López et al.   Nature Reviews Endocrinology

Role of Transient Receptor Potential Channels in Paclitaxel- and Oxaliplatin-induced Peripheral Neuropathy

(2016) Kyoji Taguchi   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

A review on phytochemistry and pharmacological activities of the processed lateral root of Aconitum carmichaelii Debeaux

(2015) Guohong Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction

(2014) Anna Mietelska-Porowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Phosphorylation of Human Tau Protein by Microtubule Affinity-Regulating Kinase 2

(2013) Martin Schwalbe et al.   BIOCHEMISTRY

Alkaloids Isolated from the Lateral Root of Aconitum carmichaelii

(2012) Liang Xiong et al.   MOLECULES

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation

(2010) Valérie Vingtdeux et al.   FASEB JOURNAL

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL