Gut Microbiota and Its Metabolite Deoxycholic Acid Contribute to Sucralose Consumption-Induced Nonalcoholic Fatty Liver Disease

Heating of food containing sucralose might result in the generation of potentially toxic chlorinated compounds

(2020) Andreas Eisenreich et al.   FOOD CHEMISTRY

Quantitative proteomics reveals systematic dysregulations of liver protein metabolism in sucralose-treated mice

(2019) Chih-Wei Liu et al.   Journal of Proteomics

Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model

(2019) Hong Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Revisited: Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota

(2019) Susan S. Schiffman et al.   FOOD AND CHEMICAL TOXICOLOGY

New insights and therapeutic implication of gut microbiota in non-alcoholic fatty liver disease and its associated liver cancer

(2019) Niama Ezzaidi et al.   CANCER LETTERS

Apple Polyphenol Extract Alleviates High-Fat-Diet-Induced Hepatic Steatosis in Male C57BL/6 Mice by Targeting LKB1/AMPK Pathway

(2019) Deming Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bile acids, microbiota and metabolism

(2018) Sarah A. Taylor et al.   HEPATOLOGY

OUP accepted manuscript

(2018)   Advances in Nutrition

Saccharin induced liver inflammation in mice by altering the gut microbiota and its metabolic functions

(2017) Xiaoming Bian et al.   FOOD AND CHEMICAL TOXICOLOGY

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

(2017) Oscar Chávez-Talavera et al.   GASTROENTEROLOGY

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

(2017) Na Jiao et al.   GUT

A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota

(2017) Belén Rivero-Gutiérrez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Pectic Bee Pollen Polysaccharide from Rosa rugosa Alleviates Diet-Induced Hepatic Steatosis and Insulin Resistance via Induction of AMPK/mTOR-Mediated Autophagy

(2017) Xinzhi Li et al.   MOLECULES

AMPK as a Therapeutic Target for Treating Metabolic Diseases

(2017) Emily A. Day et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Strategies to promote abundance of Akkermansia muciniphila , an emerging probiotics in the gut, evidence from dietary intervention studies

(2017) Kequan Zhou   Journal of Functional Foods

Flos Lonicera Combined with Metformin Ameliorates Hepatosteatosis and Glucose Intolerance in Association with Gut Microbiota Modulation

(2017) Na R. Shin et al.   Frontiers in Microbiology

Gut Microbiome Response to Sucralose and Its Potential Role in Inducing Liver Inflammation in Mice

(2017) Xiaoming Bian et al.   Frontiers in Physiology

Treatment of nonalcoholic fatty liver disease: role of AMPK

(2016) Brennan K. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Activation of bile acid signaling improves metabolic phenotypes in high-fat diet-induced obese mice

(2016) Joseph F. Pierre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

(2016) Juan P. Arab et al.   HEPATOLOGY

Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions

(2016) Sebastian Langer et al.   JOURNAL OF NEPHROLOGY

Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

(2015) Brian C. Ferslew et al.   DIGESTIVE DISEASES AND SCIENCES

Alterations of the human gut microbiome in liver cirrhosis

(2014) Nan Qin et al.   NATURE

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

Pleiotropic Roles of Bile Acids in Metabolism

(2013) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12 -Hydroxylated Bile Acids

(2013) R. A. Haeusler et al.   DIABETES

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

Bile Acid Receptor Activation Modulates Hepatic Monocyte Activity and Improves Nonalcoholic Fatty Liver Disease

(2013) Rachel H. McMahan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Bile acid receptors as targets for drug development

(2013) Frank G. Schaap et al.   Nature Reviews Gastroenterology & Hepatology

Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance

(2013) Yongjie Ma et al.   PHARMACEUTICAL RESEARCH

Low-calorie sweetener consumption is increasing in the United States

(2012) A. C. Sylvetsky et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease

(2012) Hae-Ki Min et al.   Cell Metabolism

Nonnutritive Sweeteners: Current Use and Health Perspectives: A Scientific Statement from the American Heart Association and the American Diabetes Association

(2012) C. Gardner et al.   DIABETES CARE

Position of the Academy of Nutrition and Dietetics: Use of Nutritive and Nonnutritive Sweeteners

(2012) Cindy Fitch et al.   Journal of the Academy of Nutrition and Dietetics

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults

(2011) Bertrand Cariou et al.   Nutrition & Metabolism

Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism

(2010) Gemma Brufau et al.   HEPATOLOGY

Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease

(2010) Zhao-Xia Yang et al.   Hepatology International

The gut-liver axis in nonalcoholic fatty liver disease: Another pathway to insulin resistance?

(2009) Ester Vanni et al.   HEPATOLOGY