Complex Mechanisms of Antimony Genotoxicity in Budding Yeast Involves Replication and Topoisomerase I-Associated DNA Lesions, Telomere Dysfunction and Inhibition of DNA Repair

Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair

(2020) Lok Ming Tam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

New insights into abasic site repair and tolerance

(2020) Petria S. Thompson et al.   DNA REPAIR

Antimony and its compounds: Health impacts related to pulmonary toxicity, cancer, and genotoxicity

(2020) Craig J. Boreiko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Antimony and PET bottles: Checking facts

(2020) Montserrat Filella   CHEMOSPHERE

Biological, biochemical and genotoxic effects of Sb in the midge Chironomus sancticaroli Strixino and Strixino, 1981 (Diptera: Chironomidae)

(2019) Gisele dos Santos Morais et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Disruption of Telomere Integrity and DNA Repair Machineries by KML001 Induces T Cell Senescence, Apoptosis, and Cellular Dysfunctions

(2019) Dechao Cao et al.   Frontiers in Immunology

Spatiotemporal regulation of PCNA ubiquitination in damage tolerance pathways

(2019) Yuji Masuda et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Occurrence and fate of antimony in plastics

(2019) Montserrat Filella et al.   JOURNAL OF HAZARDOUS MATERIALS

Genistein and Ascorbic Acid reduce oxidative stress-derived DNA damage induced by antileishmanial meglumine antimoniate

(2018) Luís Cláudio Lima de Jesus et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning

(2018) Luca Menin et al.   EMBO REPORTS

Error‐free DNA damage tolerance pathway is facilitated by the Irc5 translocase through cohesin

(2018) Ireneusz Litwin et al.   EMBO JOURNAL

Genotoxicity of 11 heavy metals detected as food contaminants in two human cell lines

(2017) B. Kopp et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Nucleo-mitochondrial interaction of yeast in response to cadmium sulfide quantum dot exposure

(2017) Francesco Pasquali et al.   JOURNAL OF HAZARDOUS MATERIALS

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

(2017) Alicia Ponte-Sucre et al.   PLoS Neglected Tropical Diseases

Effects of antimony on redox activities and antioxidant defence systems in sunflower (Helianthus annuus L.) plants

(2017) Alfonso Ortega et al.   PLoS One

Mitochondrial Superoxide Dismutase and Yap1p Act as a Signaling Module Contributing to Ethanol Tolerance of the Yeast Saccharomyces cerevisiae

(2016) Anna N. Zyrina et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

DNA damage tolerance by recombination: Molecular pathways and DNA structures

(2016) Dana Branzei et al.   DNA REPAIR

Cellular and molecular mechanisms of antimony transport, toxicity and resistance

(2016) Markus J. Tamás   Environmental Chemistry

Evidence for a dual role of actin in regulating chromosome organization and dynamics in yeast

(2016) Maya Spichal et al.   JOURNAL OF CELL SCIENCE

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability

(2016) Yves Pommier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction

(2016) Ye Cheng et al.   Oncotarget

Assembly of Slx4 signaling complexes behind DNA replication forks

(2015) A. Balint et al.   EMBO JOURNAL

New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk

(2015) David Kirkland et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Antimony induces oxidative stress and cell death in normal hepatocytes

(2015) Mahmoud Hashemzaei et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Mitochondria are the main source and one of the targets of Pb (lead)-induced oxidative stress in the yeast Saccharomyces cerevisiae

(2014) Cátia A. Sousa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effects of storage temperature and duration on release of antimony and bisphenol A from polyethylene terephthalate drinking water bottles of China

(2014) Ying-Ying Fan et al.   ENVIRONMENTAL POLLUTION

Synthetic Cytotoxicity: Digenic Interactions with TEL1/ATM Mutations Reveal Sensitivity to Low Doses of Camptothecin

(2014) Xuesong Li et al.   GENETICS

Arsenite Binds to the RING Finger Domains of RNF20-RNF40 Histone E3 Ubiquitin Ligase and Inhibits DNA Double-Strand Break Repair

(2014) Fan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance

(2014) Chi Kwan Tsang et al.   Nature Communications

End-joining inhibition at telomeres requires the translocase and polySUMO-dependent ubiquitin ligase Uls1

(2013) Rachel Lescasse et al.   EMBO JOURNAL

Rad51 replication fork recruitment is required for DNA damage tolerance

(2013) Román González-Prieto et al.   EMBO JOURNAL

Cuz1/Ynl155w, a Zinc-dependent Ubiquitin-binding Protein, Protects Cells from Metalloid-induced Proteotoxicity

(2013) John Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

Oxidative stress in mice treated with antileishmanial meglumine antimoniate

(2013) D.B. Bento et al.   RESEARCH IN VETERINARY SCIENCE

Nucleotide Excision Repair in Eukaryotes

(2013) O. D. Scharer   Cold Spring Harbor Perspectives in Biology

Oxidative Stress and Replication-Independent DNA Breakage Induced by Arsenic in Saccharomyces cerevisiae

(2013) Ireneusz Litwin et al.   PLoS Genetics

Everything You Ever Wanted to Know About Saccharomyces cerevisiae Telomeres: Beginning to End

(2012) R. J. Wellinger et al.   GENETICS

Arsenic and Antimony Transporters in Eukaryotes

(2012) Ewa Maciaszczyk-Dziubinska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Greater binding affinity of trivalent antimony to a CCCH zinc finger domain compared to a CCHC domain of kinetoplastid proteins

(2012) Frédéric Frézard et al.   Metallomics

Eukaryotic DNA damage checkpoint activation in response to double-strand breaks

(2011) Karen Finn et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Genetic and epigenetic effects of environmental arsenicals

(2011) Toby G. Rossman et al.   Metallomics

Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease

(2011) Wenjian Ma et al.   PLoS Genetics

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Antimony Impairs Nucleotide Excision Repair: XPA and XPE as Potential Molecular Targets

(2010) Claudia Grosskopf et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

(2010) Eleni P Mimitou et al.   EMBO JOURNAL

Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping

(2010) James M Dewar et al.   EMBO JOURNAL

Telomere capping in non-dividing yeast cells requires Yku and Rap1

(2010) Momchil D Vodenicharov et al.   EMBO JOURNAL

Trivalent Arsenic Inhibits the Functions of Chaperonin Complex

(2010) X. Pan et al.   GENETICS

Probing interactions of antimony species with DNA by short column capillary electrophoresis coupled with inductively coupled plasma mass spectrometry

(2010) Yan Li et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Heavy metal pollution of the world largest antimony mine-affected agricultural soils in Hunan province (China)

(2010) Xiangqin Wang et al.   JOURNAL OF SOILS AND SEDIMENTS

Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair

(2010) Jean S McGee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Measuring oxidative DNA damage and DNA repair using the yeast comet assay

(2010) Flávio Azevedo et al.   YEAST

Antimony Toxicity

(2010) Shyam Sundar et al.   International Journal of Environmental Research and Public Health

Replication and Recombination Factors Contributing to Recombination-Dependent Bypass of DNA Lesions by Template Switch

(2010) Fabio Vanoli et al.   PLoS Genetics

Shelterin-Like Proteins and Yku Inhibit Nucleolytic Processing of Saccharomyces cerevisiae Telomeres

(2010) Diego Bonetti et al.   PLoS Genetics

Genotoxic effects of the antileishmanial drug glucantime®

(2009) Mayara Ingrid Sousa Lima et al.   ARCHIVES OF TOXICOLOGY

Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae

(2009) Michael Thorsen et al.   BMC GENOMICS

Molecular Basis of Antimony Treatment in Leishmaniasis†

(2009) Paola Baiocco et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genotoxicity Studies of Heavy Metals: Lead, Bismuth, Indium, Silver and Antimony

(2009) Keiko Asakura et al.   JOURNAL OF OCCUPATIONAL HEALTH

Perspectives of antimony compounds in oncology

(2008) Pankaj SHARMA et al.   ACTA PHARMACOLOGICA SINICA

Redox control and oxidative stress in yeast cells

(2008) Enrique Herrero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

KML001 Cytotoxic Activity Is Associated with Its Binding to Telomeric Sequences and Telomere Erosion in Prostate Cancer Cells

(2008) P. Phatak et al.   CLINICAL CANCER RESEARCH

The Yku70–Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle

(2008) Michela Clerici et al.   EMBO REPORTS

Dynamic Regulation of Single-Stranded Telomeres in Saccharomyces cerevisiae

(2008) S. Smith et al.   GENETICS

Differential Regulation of the Cellular Response to DNA Double-Strand Breaks in G1

(2008) Jacqueline H. Barlow et al.   MOLECULAR CELL

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis

(2008) Wenjian Ma et al.   NUCLEIC ACIDS RESEARCH