Susceptibility and Severity of Viral Infections in Obesity: Lessons from Influenza to COVID-19. Does Leptin Play a Role?
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Title
Susceptibility and Severity of Viral Infections in Obesity: Lessons from Influenza to COVID-19. Does Leptin Play a Role?
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 6, Pages 3183
Publisher
MDPI AG
Online
2021-03-22
DOI
10.3390/ijms22063183
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Note: Only part of the references are listed.- Diabetes, obesity, metabolism and SARS-CoV-2 infection: The end of the beginning
- (2021) Daniel J. Drucker Cell Metabolism
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- (2021) Jingya Wang et al. JOURNAL OF LEUKOCYTE BIOLOGY
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- Obesity-Related Microenvironment Promotes Emergence of Virulent Influenza Virus Strains
- (2020) Rebekah Honce et al. mBio
- The emergence of SARS, MERS and novel SARS-2 coronaviruses in the 21st century
- (2020) Vivaldo Gomes da Costa et al. ARCHIVES OF VIROLOGY
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Obesity a Risk Factor for Severe COVID-19 Infection: Multiple Potential Mechanisms
- (2020) Naveed Sattar et al. CIRCULATION
- Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
- (2020) Safiya Richardson et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Obesity could shift severe COVID-19 disease to younger ages
- (2020) David A Kass et al. LANCET
- High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation
- (2020) Arthur Simonnet et al. Obesity
- COVID 19 and the Patient with Obesity – The Editors Speak Out
- (2020) Donna H. Ryan et al. Obesity
- SARS-CoV-2 in Spanish Intensive Care Units: Early experience with 15-day survival in Vitoria
- (2020) Helena Barrasa et al. Anaesthesia Critical Care & Pain Medicine
- Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis
- (2020) Ana Campos Codo et al. Cell Metabolism
- COVID-19, SARS and MERS: are they closely related?
- (2020) N. Petrosillo et al. CLINICAL MICROBIOLOGY AND INFECTION
- SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls
- (2020) Nina Le Bert et al. NATURE
- Obesity and mortality of COVID-19. Meta-analysis
- (2020) Abdulzahra Hussain et al. Obesity Research & Clinical Practice
- Obesity prolongs the hospital stay in patients affected by COVID-19, and may impact on SARS-COV-2 shedding
- (2020) Diego Moriconi et al. Obesity Research & Clinical Practice
- Individuals with obesity and COVID‐19: A global perspective on the epidemiology and biological relationships
- (2020) Barry M. Popkin et al. Obesity Reviews
- Pathophysiology of Cardiovascular Complications in COVID-19
- (2020) Vladimir Petrovic et al. Frontiers in Physiology
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- Obesity Increases the Severity and Mortality of Influenza and COVID-19: A Systematic Review and Meta-Analysis
- (2020) Xue Zhao et al. Frontiers in Endocrinology
- Impact of Obesity on Influenza A Virus Pathogenesis, Immune Response, and Evolution
- (2019) Rebekah Honce et al. Frontiers in Immunology
- Tissue Immune Cells Fuel Obesity-Associated Inflammation in Adipose Tissue and Beyond
- (2019) Rui Liu et al. Frontiers in Immunology
- Specific Biological Features of Adipose Tissue, and Their Impact on HIV Persistence
- (2019) Christine Bourgeois et al. Frontiers in Microbiology
- OUP accepted manuscript
- (2018) JOURNAL OF INFECTIOUS DISEASES
- Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community
- (2018) Jing Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Influenza Cataclysm, 1918
- (2018) David M. Morens et al. NEW ENGLAND JOURNAL OF MEDICINE
- Leptin Functions in Infectious Diseases
- (2018) Radheshyam Maurya et al. Frontiers in Immunology
- B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection
- (2017) Rasagna Kosaraju et al. JOURNAL OF IMMUNOLOGY
- The impact of obesity and timely antiviral administration on severe influenza outcomes among hospitalized adults
- (2017) Hannah E. Segaloff et al. JOURNAL OF MEDICAL VIROLOGY
- Obesity and malnutrition similarly alter the renin–angiotensin system and inflammation in mice and human adipose
- (2017) Thales de Almeida Pinheiro et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Cardiovascular consequences of metabolic syndrome
- (2017) Johnathan D. Tune et al. Translational Research
- Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue
- (2017) Tsuyoshi Uchiyama et al. PLoS One
- Link between Metabolic Syndrome and Insulin Resistance
- (2016) Zoran Gluvic et al. Current Vascular Pharmacology
- Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis
- (2016) Alaa Badawi et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- ‘Adipaging’: ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue
- (2016) Laura M. Pérez et al. JOURNAL OF PHYSIOLOGY-LONDON
- Leptin inhibitors from fungal endophytes (LIFEs): Will be novel therapeutic drugs for obesity and its associated immune mediated diseases
- (2016) K. Chandra Mouli et al. MEDICAL HYPOTHESES
- Obesity decreases B cell responses in young and elderly individuals
- (2016) Daniela Frasca et al. Obesity
- Metabolic control of immune tolerance in health and autoimmunity
- (2016) Fortunata Carbone et al. SEMINARS IN IMMUNOLOGY
- Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance
- (2015) Philip C. Calder BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages
- (2015) Yi Zhou et al. Cell Metabolism
- Regular Exercise Enhances the Immune Response Against Microbial Antigens Through Up-Regulation of Toll-like Receptor Signaling Pathways
- (2015) Qishi Zheng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The effect of lipopolysaccharide-induced obesity and its chronic inflammation on influenza virus-related pathology
- (2015) Sun-Young Ahn et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Obesity and Risk of Infection
- (2015) Kathrine Agergård Kaspersen et al. EPIDEMIOLOGY
- Leptin Is Oversecreted by Respiratory Syncytial Virus-Infected Bronchial Epithelial Cells and Regulates Th2 and Th17 Cell Differentiation
- (2015) Ling Qin et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice
- (2015) J. Justin Milner et al. JOURNAL OF IMMUNOLOGY
- Leptin Receptor Signaling in T Cells Is Required for Th17 Differentiation
- (2015) Bernardo S. Reis et al. JOURNAL OF IMMUNOLOGY
- Clinician-Patient Risk Discussion for Atherosclerotic Cardiovascular Disease Prevention
- (2015) Seth S. Martin et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Interaction of obesity and infections
- (2015) N. V. Dhurandhar et al. Obesity Reviews
- Leptin resistance in diet-induced obesity: the role of hypothalamic inflammation
- (2015) K. C. G. de Git et al. Obesity Reviews
- Obesity – a risk factor for postoperative complications in general surgery?
- (2015) Elke E.K.M. Tjeertes et al. BMC Anesthesiology
- Obesity Impairs γδ T Cell Homeostasis and Antiviral Function in Humans
- (2015) Anne E. Costanzo et al. PLoS One
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- (2015) Kristi J. Warren et al. PLoS One
- Clinical Course and Outcomes of Critically Ill Patients With Middle East Respiratory Syndrome Coronavirus Infection
- (2014) Yaseen M. Arabi et al. ANNALS OF INTERNAL MEDICINE
- Middle East respiratory syndrome coronavirus (MERS-CoV) viral shedding in the respiratory tract: an observational analysis with infection control implications
- (2014) Ziad A. Memish et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Impaired Clearance of Influenza A Virus in Obese, Leptin Receptor Deficient Mice Is Independent of Leptin Signaling in the Lung Epithelium and Macrophages
- (2014) Kathryn A. Radigan et al. PLoS One
- Effects of chronic leptin infusion on subsequent body weight and composition in mice: Can body weight set point be reset?a
- (2014) Y. Ravussin et al. Molecular Metabolism
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- (2013) Niki D. Ubags et al. CRITICAL CARE MEDICINE
- Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection
- (2013) D O'Shea et al. INTERNATIONAL JOURNAL OF OBESITY
- Obesity and nosocomial infections
- (2013) R. Huttunen et al. JOURNAL OF HOSPITAL INFECTION
- Viral Antigen Induces Differentiation of Foxp3+ Natural Regulatory T Cells in Influenza Virus-Infected Mice
- (2013) F. Bedoya et al. JOURNAL OF IMMUNOLOGY
- Diet-Induced Obese Mice Exhibit Altered Heterologous Immunity during a Secondary 2009 Pandemic H1N1 Infection
- (2013) J. J. Milner et al. JOURNAL OF IMMUNOLOGY
- Leptin Mediates the Pathogenesis of Severe 2009 Pandemic Influenza A(H1N1) Infection Associated With Cytokine Dysregulation in Mice With Diet-Induced Obesity
- (2013) Anna J. X. Zhang et al. JOURNAL OF INFECTIOUS DISEASES
- Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study
- (2013) Abdullah Assiri et al. LANCET INFECTIOUS DISEASES
- Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus
- (2013) Abdullah Assiri et al. NEW ENGLAND JOURNAL OF MEDICINE
- Overweight and obese adult humans have a defective cellular immune response to pandemic H1N1 Influenza a virus
- (2013) Heather A. Paich et al. Obesity
- Body mass index and risk of pneumonia: a systematic review and meta-analysis
- (2013) D. T. Phung et al. Obesity Reviews
- Viral Pneumonitis Is Increased in Obese Patients during the First Wave of Pandemic A(H1N1) 2009 Virus
- (2013) Jen Kok et al. PLoS One
- Leptin-based adjuvants: An innovative approach to improve vaccine response
- (2013) Sarah J. White et al. VACCINE
- Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells
- (2013) Satoko Arai et al. Cell Reports
- Leptin signaling and leptin resistance
- (2013) Yingjiang Zhou et al. Frontiers of Medicine
- Obesity and cancer risk: evidence, mechanisms, and recommendations
- (2012) Ivana Vucenik et al. Annals of the New York Academy of Sciences
- Modulation of Leptin Resistance by Protein Tyrosine Phosphatases
- (2012) Julie St-Pierre et al. Cell Metabolism
- Bone structure and B-cell populations, crippled by obesity, are partially rescued by brief daily exposure to low-magnitude mechanical signals
- (2012) M. Ete Chan et al. FASEB JOURNAL
- Obesity and the risk and outcome of infection
- (2012) R Huttunen et al. INTERNATIONAL JOURNAL OF OBESITY
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Decreased interferon-α and interferon-β production in obesity and expression of suppressor of cytokine signaling
- (2012) Eli Teran-Cabanillas et al. NUTRITION
- The impact of obesity on the immune response to infection
- (2012) J. Justin Milner et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- The Impact of Obesity on Urinary Tract Infection Risk
- (2012) Michelle J. Semins et al. UROLOGY
- Obese Patients and Mechanical Circulatory Support: Weight Loss, Adverse Events, and Outcomes
- (2011) Firas Zahr et al. ANNALS OF THORACIC SURGERY
- Obesity and Respiratory Hospitalizations During Influenza Seasons in Ontario, Canada: A Cohort Study
- (2011) J. C. Kwong et al. CLINICAL INFECTIOUS DISEASES
- A Novel Risk Factor for a Novel Virus: Obesity and 2009 Pandemic Influenza A (H1N1)
- (2011) J. K. Louie et al. CLINICAL INFECTIOUS DISEASES
- Obesity is associated with impaired immune response to influenza vaccination in humans
- (2011) P A Sheridan et al. INTERNATIONAL JOURNAL OF OBESITY
- Influenza A Viral Replication Is Blocked by Inhibition of the Inositol-requiring Enzyme 1 (IRE1) Stress Pathway
- (2011) Ihab H. Hassan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired Wound Healing Predisposes Obese Mice to Severe Influenza Virus Infection
- (2011) Kevin B. O’Brien et al. JOURNAL OF INFECTIOUS DISEASES
- Leptin as an immunomodulator
- (2011) Claudio Procaccini et al. MOLECULAR ASPECTS OF MEDICINE
- B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
- (2011) Daniel A Winer et al. NATURE MEDICINE
- Ten years of leptin replacement therapy
- (2011) G. Paz-Filho et al. Obesity Reviews
- Obesity is associated with higher risk of intensive care unit admission and death in influenza A (H1N1) patients: a systematic review and meta-analysis
- (2011) L. Fezeu et al. Obesity Reviews
- Mucosal co-immunization of mice with recombinant lactococci secreting VapA antigen and leptin elicits a protective immune response against Rhodococcus equi infection
- (2011) S. Cauchard et al. VACCINE
- Impact of Obesity in Patients Infected With 2009 Influenza A(H1N1)
- (2010) Emili Díaz et al. CHEST
- An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness
- (2010) Claudio Procaccini et al. IMMUNITY
- Foxp3+ CD4 Regulatory T Cells Limit Pulmonary Immunopathology by Modulating the CD8 T Cell Response during Respiratory Syncytial Virus Infection
- (2010) R. B. Fulton et al. JOURNAL OF IMMUNOLOGY
- Leptin Exacerbates Sepsis-Mediated Morbidity and Mortality
- (2010) N. I. Shapiro et al. JOURNAL OF IMMUNOLOGY
- Percent Body Fat and Prediction of Surgical Site Infection
- (2010) Emily Waisbren et al. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
- Obesity and the outcome of infection
- (2010) Reetta Huttunen et al. LANCET INFECTIOUS DISEASES
- Role of Leptin in the Activation of Immune Cells
- (2010) Patricia Fernández-Riejos et al. MEDIATORS OF INFLAMMATION
- Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica
- (2010) X Guo et al. Mucosal Immunology
- Influence of body mass index on outcome of the mechanically ventilated patients
- (2010) A. Anzueto et al. THORAX
- Plasma n-3 polyunsaturated fatty acids are negatively associated with obesity
- (2009) Michelle Micallef et al. BRITISH JOURNAL OF NUTRITION
- Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
- (2009) Lale Ozcan et al. Cell Metabolism
- The impact of obesity on outcomes after critical illness: a meta-analysis
- (2009) Charles W. Hogue et al. INTENSIVE CARE MEDICINE
- Effect of body mass index on the outcome of infections: a systematic review
- (2009) M. E. Falagas et al. Obesity Reviews
- Resistance of Janus Kinase-2 Dependent Leptin Signaling in Natural Killer (NK) Cells: A Novel Mechanism of NK Cell Dysfunction in Diet-Induced Obesity
- (2008) Heike Nave et al. ENDOCRINOLOGY
- Leptin Receptor Signaling is Required for Vaccine-Induced Protection Against Helicobacter pylori
- (2008) Andrea Wehrens et al. HELICOBACTER
- Leptin Resistance
- (2008) Seth S. Martin et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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