Development of Covalent Chitosan-Polyethylenimine Derivatives as Gene Delivery Vehicle: Synthesis, Characterization, and Evaluation

MgO/carboxymethyl chitosan nanocomposite improves thermal stability, waterproof and antibacterial performance for food packaging

(2020) Yanbo Wang et al.   CARBOHYDRATE POLYMERS

3D Hierarchical, Nanostructured Chitosan/PLA/HA Scaffolds Doped with TiO2/Au/Pt NPs with Tunable Properties for Guided Bone Tissue Engineering

(2020) Julia Radwan-Pragłowska et al.   Polymers

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

(2020) Andrew V. Anzalone et al.   NATURE BIOTECHNOLOGY

Selection of Water-Soluble Chitosan by Microwave-Assisted Degradation and pH-Controlled Precipitation

(2020) Céline M. A. Journot et al.   Polymers

Benzylguanidine and Galactose Double-Conjugated Chitosan Nanoparticles with Reduction Responsiveness for Targeted Delivery of Doxorubicin to CXCR 4 Positive Tumors

(2020) Fei Kong et al.   BIOCONJUGATE CHEMISTRY

Current Clinical Applications of In Vivo Gene Therapy with AAVs

(2020) Jerry R. Mendell et al.   MOLECULAR THERAPY

Optimization of Dexamethasone Administration for Maintaining Global Transduction Efficacy of Adeno-Associated Virus Serotype 9

(2019) Zheng Chai et al.   HUMAN GENE THERAPY

Chitosan for gene delivery: Methods for improvement and applications

(2019) Di Chuan et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Recent Advances in Chitosan-Based Carriers for Gene Delivery

(2019) Ye Cao et al.   Marine Drugs

Kinetic Control in Assembly of Plasmid DNA/Polycation Complex Nanoparticles

(2019) Yizong Hu et al.   ACS Nano

Development and Clinical Translation of Approved Gene Therapy Products for Genetic Disorders

(2019) Alireza Shahryari et al.   Frontiers in Genetics

Biodegradable Polymers for Gene Delivery

(2019) T. J. Thomas et al.   MOLECULES

RGD/TAT-functionalized chitosan- graft -PEI-PEG gene nanovector for sustained delivery of NT-3 for potential application in neural regeneration

(2018) Dongni Wu et al.   Acta Biomaterialia

Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree

(2018) Natalie Lie Berntsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

Chitosan in Non-Viral Gene Delivery: Role of Structure, Characterization Methods, and Insights in Cancer and Rare Diseases Therapies

(2018) Beatriz Santos-Carballal et al.   Polymers

Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems

(2018) M. Danaei et al.   Pharmaceutics

Overcoming Endosomal Entrapment in Drug Delivery

(2018) Dehua Pei et al.   BIOCONJUGATE CHEMISTRY

Polycations for Gene Delivery: Dilemmas and Solutions

(2018) Jie Chen et al.   BIOCONJUGATE CHEMISTRY

The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery

(2018) Samuel A. Smith et al.   BIOCONJUGATE CHEMISTRY

Bait-and-Switch Supramolecular Strategy To Generate Noncationic RNA–Polymer Complexes for RNA Delivery

(2018) Ziwen Jiang et al.   BIOMACROMOLECULES

Recent progress in the structural modification of chitosan for applications in diversified biomedical fields

(2018) Hemant Mittal et al.   EUROPEAN POLYMER JOURNAL

Heparin binding chitosan derivatives for production of pro-angiogenic hydrogels for promoting tissue healing

(2017) Muhammad Yar et al.   Materials Science & Engineering C-Materials for Biological Applications

Polyplex Evolution: Understanding Biology, Optimizing Performance

(2017) Arnaldur Hall et al.   MOLECULAR THERAPY

Chitosan and its derivatives: vectors in gene therapy

(2017) A S Kritchenkov et al.   RUSSIAN CHEMICAL REVIEWS

Polyethylenimine: a very useful ionic polymer in the design of immobilized enzyme biocatalysts

(2017) Jose J. Virgen-Ortíz et al.   Journal of Materials Chemistry B

Advances in Non-Viral DNA Vectors for Gene Therapy

(2017) Cinnamon Hardee et al.   Genes

Low-Dose Gene Therapy for Murine PKU Using Episomal Naked DNA Vectors Expressing PAH from Its Endogenous Liver Promoter

(2017) Hiu Man Grisch-Chan et al.   Molecular Therapy-Nucleic Acids

Recent Advances in Nanomaterials for Gene Delivery—A Review

(2017) Michael Riley et al.   Nanomaterials

Linear and Branched PEIs (Polyethylenimines) and Their Property Space

(2016) Claudiu Lungu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Overcoming Gene-Delivery Hurdles: Physiological Considerations for Nonviral Vectors

(2016) Andrew B. Hill et al.   TRENDS IN BIOTECHNOLOGY

CD44 Mediated Nonviral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic-Acid-Coated Nanoparticles

(2016) Jonathan Yen et al.   ACS Biomaterials-Science & Engineering

CD44 Mediated Nonviral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic-Acid-Coated Nanoparticles

(2016) Jonathan Yen et al.   ACS Biomaterials Science & Engineering

A Biodegradable Polyethylenimine-Based Vector Modified by Trifunctional Peptide R18 for Enhancing Gene Transfection Efficiency In Vivo

(2016) Jing Hu et al.   PLoS One

Preparation of arginine modified PEI-conjugated chitosan copolymer for DNA delivery

(2015) Xi Zhang et al.   CARBOHYDRATE POLYMERS

Synthesis of Tat tagged and folate modified N-succinyl-chitosan self-assembly nanoparticles as a novel gene vector

(2015) Cheng-yun Yan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Liver-targeted gene therapy: Approaches and challenges

(2015) Rajagopal N. Aravalli et al.   LIVER TRANSPLANTATION

Tuning the Buffering Capacity of Polyethylenimine with Glycerol Molecules for Efficient Gene Delivery: Staying In or Out of the Endosomes

(2015) Bijay Singh et al.   MACROMOLECULAR BIOSCIENCE

Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study

(2015) Ole B Suhr et al.   Orphanet Journal of Rare Diseases

Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain

(2015) Panagiotis Mastorakos et al.   Advanced Healthcare Materials

Computationally designed liver-specific transcriptional modules and hyperactive factor IX improve hepatic gene therapy

(2014) N. Nair et al.   BLOOD

Treatment of phenylketonuria using minicircle-based naked-DNA gene transfer to murine liver

(2014) Hiu Man Viecelli et al.   HEPATOLOGY

Chitosan-Graft-Polyethylenimine/DNA Nanoparticles as Novel Non-Viral Gene Delivery Vectors Targeting Osteoarthritis

(2014) Huading Lu et al.   PLoS One

Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers

(2014) Lian Jin et al.   Theranostics

Gene therapy and DNA delivery systems

(2013) D. Ibraheem et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Physicochemical Properties Determine Nanomaterial Cellular Uptake, Transport, and Fate

(2012) Motao Zhu et al.   ACCOUNTS OF CHEMICAL RESEARCH

OMERO: flexible, model-driven data management for experimental biology

(2012) Chris Allan et al.   NATURE METHODS

Poly(ethylene glycol) analogs grafted with low molecular weight poly(ethylene imine) as non-viral gene vectors

(2010) Zhenfang Zhang et al.   Acta Biomaterialia

Biodegradation, biodistribution and toxicity of chitosan

(2009) T. Kean et al.   ADVANCED DRUG DELIVERY REVIEWS

Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting

(2009) Hu-Lin Jiang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity

(2009) Jian-Qing Gao et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

N-Succinyl-chitosan grafted with low molecular weight polyethylenimine as a serum-resistant gene vector

(2009) Bo Lu et al.   Molecular BioSystems

Transient Pretreatment With Glucocorticoid Ablates Innate Toxicity of Systemically Delivered Adenoviral Vectors Without Reducing Efficacy

(2009) Sergey S Seregin et al.   MOLECULAR THERAPY

Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer

(2008) Jun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Low Molecular Weight Polyethylenimine GraftedN-Maleated Chitosan for Gene Delivery: Properties and In Vitro Transfection Studies

(2008) Bo Lu et al.   BIOMACROMOLECULES

Systemic Delivery of DNA or siRNA Mediated by Linear Polyethylenimine (L-PEI) Does Not Induce an Inflammatory Response

(2008) Marie-Elise Bonnet et al.   PHARMACEUTICAL RESEARCH

Assessing the Effect of Surface Chemistry on Gold Nanorod Uptake, Toxicity, and Gene Expression in Mammalian Cells

(2007) Tanya S. Hauck et al.   Small