Measurement of Interpeptidic CuII Exchange Rate Constants of CuII-Amyloid-β Complexes to Small Peptide Motifs by Tryptophan Fluorescence Quenching

Key Intermediate Species Reveal the Copper(II)‐Exchange Pathway in Biorelevant ATCUN/NTS Complexes

(2020) Radosław Kotuniak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper(II)-binding equilibria in human blood

(2020) Tiina Kirsipuu et al.   Scientific Reports

Open questions on the biological roles of first-row transition metals

(2020) Debbie C. Crans et al.   Communications Chemistry

N‐truncated Aβ peptides impact on Cu and Cu(Aβ)‐generated ROS: Cu(I) matters !

(2020) Charlène Esmieu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Aβ5–x Peptides: N-Terminal Truncation Yields Tunable Cu(II) Complexes

(2020) Nina E. Wezynfeld et al.   INORGANIC CHEMISTRY

Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate

(2020) Karolina Bossak-Ahmad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CuII Binding Properties of N-Truncated Aβ Peptides: In Search of Biological Function

(2019) Ewelina Stefaniak et al.   INORGANIC CHEMISTRY

Management of oxidative stress and other pathologies in Alzheimer’s disease

(2019) Miriama Simunkova et al.   ARCHIVES OF TOXICOLOGY

The role of zinc, copper, manganese and iron in neurodegenerative diseases

(2019) Leda Mezzaroba et al.   NEUROTOXICOLOGY

Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways

(2019) Wen-hui Ma et al.   LIFE SCIENCES

N-Terminal Cu-Binding Motifs (Xxx-Zzz-His, Xxx-His) and Their Derivatives: Chemistry, Biology and Medicinal Applications

(2018) Paulina Gonzalez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance

(2018) Elena Atrián-Blasco et al.   COORDINATION CHEMISTRY REVIEWS

Measurement of Interpeptidic Cu(II) Exchange Rate Constants by Static Fluorescence Quenching of Tryptophan

(2018) Cheryle N. Beuning et al.   INORGANIC CHEMISTRY

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

(2018) Loren Pickart et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Pivotal Role of Copper in Neurodegeneration: A New Strategy for the Therapy of Neurodegenerative Disorders

(2018) Roberta Giampietro et al.   MOLECULAR PHARMACEUTICS

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

CuII Binding to Various Forms of Amyloid-β Peptides: Are They Friends or Foes?

(2017) Valentina Borghesani et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis

(2017) Xinying Wang et al.   WOUND REPAIR AND REGENERATION

Resistance of Cu(Aβ4- 16) to Copper Capture by Metallothionein-3 Supports a Function for the Aβ4- 42 Peptide as a Synaptic CuII Scavenger

(2016) Nina E. Wezynfeld et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding

(2015) Mariusz Mital et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Truncated Amyloid-β(11–40/42)from Alzheimer Disease Binds Cu2+with a Femtomolar Affinity and Influences Fiber Assembly

(2015) Joseph D. Barritt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Introduction of a Fluorescent Probe to Amyloid-β to Reveal Kinetic Insights into Its Interactions with Copper(II)

(2014) Thomas Branch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intrinsic Tryptophan Fluorescence in the Detection and Analysis of Proteins: A Focus on Förster Resonance Energy Transfer Techniques

(2014) Amar Ghisaidoobe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Binding of transition metal ions to albumin: Sites, affinities and rates

(2013) Wojciech Bal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Copper and Heme-Mediated Abeta Toxicity: Redox Chemistry, Abeta Oxidations and Anti-ROS Compounds

(2013) Stefan Chassaing et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide

(2013) Peter Faller et al.   INORGANIC CHEMISTRY

The role of metal ions in amyloid formation: general principles from model peptides

(2013) Bruno Alies et al.   Metallomics

34 GHz Pulsed ENDOR Characterization of the Copper Coordination of an Amyloid β Peptide Relevant to Alzheimer’s Disease

(2012) Donghun Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Elevated Copper Binding Strength of Amyloid-β Aggregates Allows the Sequestration of Copper from Albumin: A Pathway to Accumulation of Copper in Senile Plaques

(2012) Dianlu Jiang et al.   BIOCHEMISTRY

Coordination of redox active metal ions to the amyloid precursor protein and to amyloid-β peptides involved in Alzheimer disease. Part 2: Dependence of Cu(II) binding sites with Aβ sequences

(2012) Christelle Hureau et al.   COORDINATION CHEMISTRY REVIEWS

Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)

(2012) Henryk Kozlowski et al.   COORDINATION CHEMISTRY REVIEWS

Peptides as complexing agents: Factors influencing the structure and thermodynamic stability of peptide complexes

(2012) Imre Sóvágó et al.   COORDINATION CHEMISTRY REVIEWS

The Heterogeneous Nature of Cu2+Interactions with Alzheimer’s Amyloid-β Peptide

(2011) Simon C. Drew et al.   ACCOUNTS OF CHEMICAL RESEARCH

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

(2011) Jeppe T. Pedersen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

X-ray and Solution Structures of CuIIGHK and CuIIDAHK Complexes: Influence on Their Redox Properties

(2011) Christelle Hureau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper: An essential metal in biology

(2011) Richard A. Festa et al.   CURRENT BIOLOGY

Thermodynamic study of Cu2+ binding to the DAHK and GHK peptides by isothermal titration calorimetry (ITC) with the weaker competitor glycine

(2011) Ana Trapaidze et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Substantial Contribution of the Two Imidazole Rings of the His13−His14 Dyad to Cu(II) Binding in Amyloid-β(1−16) at Physiological pH and Its Significance

(2011) Byong-kyu Shin et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Molecular-Level Examination of Cu2+Binding Structure for Amyloid Fibrils of 40-Residue Alzheimer’s β by Solid-State NMR Spectroscopy

(2011) Sudhakar Parthasarathy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantification of the Binding Properties of Cu2+to the Amyloid Beta Peptide: Coordination Spheres for Human and Rat Peptides and Implication on Cu2+-Induced Aggregation†

(2010) Lian Hong et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Biology of Amyloid: Structure, Function, and Regulation

(2010) Jason Greenwald et al.   STRUCTURE

Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1–16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues

(2009) Pierre Dorlet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper Transfer from Cu-Aβ to Human Serum Albumin Inhibits Aggregation, Radical Production and Reduces Aβ Toxicity

(2009) Lorena Perrone et al.   CHEMBIOCHEM

Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease

(2009) Andreana C. Leskovjan et al.   NEUROIMAGE

The Metal Loading Ability of β-Amyloid N-Terminus: A Combined Potentiometric and Spectroscopic Study of Copper(II) Complexes with β-Amyloid(1−16), Its Short or Mutated Peptide Fragments, and Its Polyethylene Glycol (PEG)-ylated Analogue

(2008) Chiara A. Damante et al.   INORGANIC CHEMISTRY