Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size

Alternative Lengthening of Telomeres and Differential Expression of Endocrine Transcription Factors Distinguish Metastatic and Non-metastatic Insulinomas

(2020) Wenzel M. Hackeng et al.   ENDOCRINE PATHOLOGY

Genome Methylation Accurately Predicts Neuroendocrine Tumor Origin: An Online Tool

(2020) Wenzel M. Hackeng et al.   CLINICAL CANCER RESEARCH

Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression

(2020) Annunziata Di Domenico et al.   Communications Biology

Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways

(2019) Jia-Min Zhang et al.   Cell Reports

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

(2019) Paloma Cejas et al.   NATURE MEDICINE

Whole-genome sequencing reveals distinct genetic bases for insulinomas and non-functional pancreatic neuroendocrine tumours: leading to a new classification system

(2019) Xiafei Hong et al.   GUT

Assessment of ARX expression, a novel biomarker for metastatic risk in pancreatic neuroendocrine tumors, in endoscopic ultrasound fine‐needle aspiration

(2019) Wenzel M. Hackeng et al.   DIAGNOSTIC CYTOPATHOLOGY

The North American Neuroendocrine Tumor Society Consensus Paper on the Surgical Management of Pancreatic Neuroendocrine Tumors

(2019) James R. Howe et al.   PANCREAS

Pathways Impacted by Genomic Alterations in Pulmonary Carcinoid Tumors

(2018) Michael K. Asiedu et al.   CLINICAL CANCER RESEARCH

Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times

(2018) Somak Roy et al.   GASTROENTEROLOGY

A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal

(2018) Guido Rindi et al.   MODERN PATHOLOGY

Genetic Analysis of Small Well-differentiated Pancreatic Neuroendocrine Tumors Identifies Subgroups With Differing Risks of Liver Metastases

(2018) Antonio Pea et al.   ANNALS OF SURGERY

ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup

(2018) Chang S. Chan et al.   Nature Communications

Whole-genome landscape of pancreatic neuroendocrine tumours

(2017) Aldo Scarpa et al.   NATURE

Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States

(2017) Arvind Dasari et al.   JAMA Oncology

Alternative Lengthening of Telomeres in Primary Pancreatic Neuroendocrine Tumors Is Associated with Aggressive Clinical Behavior and Poor Survival

(2016) Joo Young Kim et al.   CLINICAL CANCER RESEARCH

Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors

(2016) Aatur D. Singhi et al.   CLINICAL CANCER RESEARCH

Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role forTERT,RB1,MEN1andKMT2D

(2016) Michele Simbolo et al.   JOURNAL OF PATHOLOGY

Break-induced telomere synthesis underlies alternative telomere maintenance

(2016) Robert L. Dilley et al.   NATURE

ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors

(2016) M. Falconi et al.   NEUROENDOCRINOLOGY

Observation versus Resection for Small Asymptomatic Pancreatic Neuroendocrine Tumors: A Matched Case–Control Study

(2015) Eran Sadot et al.   ANNALS OF SURGICAL ONCOLOGY

Prognostic Impact of Novel Molecular Subtypes of Small Intestinal Neuroendocrine Tumor

(2015) A. Karpathakis et al.   CLINICAL CANCER RESEARCH

Operative Versus Nonoperative Management of Nonfunctioning Pancreatic Neuroendocrine Tumors

(2015) Irene Y. Zhang et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Erratum: Calculation of the Ki67 index in pancreatic neuroendocrine tumors: a comparative analysis of four counting methodologies

(2015) Michelle D Reid et al.   MODERN PATHOLOGY

Progesterone Receptor and PTEN Expression Predict Survival in Patients With Low- and Intermediate-Grade Pancreatic Neuroendocrine Tumors

(2014) Jeannelyn S. Estrella et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Alternative Lengthening of Telomeres Predicts Site of Origin in Neuroendocrine Tumor Liver Metastases

(2014) Epameinondas Dogeas et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Phosphohistone H3 and Ki-67 Labeling Indices in Cytologic Specimens from Well-Differentiated Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas: A Comparative Analysis Using Automated Image Cytometry

(2013) Adele D. Fung et al.   ACTA CYTOLOGICA

Grading of Well-differentiated Pancreatic Neuroendocrine Tumors Is Improved by the Inclusion of Both Ki67 Proliferative Index and Mitotic Rate

(2013) Chad M. McCall et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

A Single Institutionʼs 26-Year Experience With Nonfunctional Pancreatic Neuroendocrine Tumors

(2013) Trevor A. Ellison et al.   ANNALS OF SURGERY

Population-Level Analysis of Pancreatic Neuroendocrine Tumors 2 cm or Less in Size

(2013) Eric J. Kuo et al.   ANNALS OF SURGICAL ONCOLOGY

Loss of DAXX and ATRX Are Associated With Chromosome Instability and Reduced Survival of Patients With Pancreatic Neuroendocrine Tumors

(2013) Ilaria Marinoni et al.   GASTROENTEROLOGY

Somatic mutation of CDKN1B in small intestine neuroendocrine tumors

(2013) Joshua M Francis et al.   NATURE GENETICS

Predicting aggressive behavior in nonfunctioning pancreatic neuroendocrine tumors

(2013) Jovenel Cherenfant et al.   SURGERY

Arx is required for normal enteroendocrine cell development in mice and humans

(2012) Aiping Du et al.   DEVELOPMENTAL BIOLOGY

Implications of Incidentally Discovered, Nonfunctioning Pancreatic Endocrine Tumors

(2011) Alex B. Haynes   ARCHIVES OF SURGERY

Altered Telomeres in Tumors with ATRX and DAXX Mutations

(2011) C. M. Heaphy et al.   SCIENCE

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases

(2010) Vincenzo Corbo et al.   ENDOCRINE-RELATED CANCER