20 years of DNA Polymerase μ, the polymerase that still surprises

A novel role of DNA polymerase λ in translesion synthesis in conjunction with DNA polymerase ζ

(2021) Jung-Hoon Yoon et al.   Life Science Alliance

Polymerase μ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system

(2020) Bailin Zhao et al.   NUCLEIC ACIDS RESEARCH

Structure and function relationships in mammalian DNA polymerases

(2019) Nicole M. Hoitsma et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis

(2019) Bailin Zhao et al.   Nature Communications

Translesion and Repair DNA Polymerases: Diverse Structure and Mechanism

(2018) Wei Yang et al.   Annual Review of Biochemistry

Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining

(2018) John M. Pryor et al.   SCIENCE

Nonhomologous DNA end-joining for repair of DNA double-strand breaks

(2017) Nicholas R. Pannunzio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polμ tumor variants decrease the efficiency and accuracy of NHEJ

(2017) Guillermo Sastre-Moreno et al.   NUCLEIC ACIDS RESEARCH

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu

(2017) Andrea F. Moon et al.   NUCLEIC ACIDS RESEARCH

Time-lapse crystallography snapshots of a double-strand break repair polymerase in action

(2017) Joonas A. Jamsen et al.   Nature Communications

Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency

(2016) Howard H. Y. Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-Stage Synapsis of DNA Ends during Non-homologous End Joining

(2016) Thomas G.W. Graham et al.   MOLECULAR CELL

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair

(2015) Dylan A. Reid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creative template-dependent synthesis by human polymerase mu

(2015) Andrea F. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role for polymerase specialization in cellular nonhomologous end joining

(2015) John M. Pryor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

(2015) Agnel Sfeir et al.   TRENDS IN BIOCHEMICAL SCIENCES

Homology and enzymatic requirements of microhomology-dependent alternative end joining

(2015) S Sharma et al.   Cell Death & Disease

Phylogenetic analysis and evolutionary origins of DNA polymerase X-family members

(2014) Rachelle J. Bienstock et al.   DNA REPAIR

The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining

(2014) Crystal A. Waters et al.   Nature Communications

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

(2013) Sara García-Gómez et al.   MOLECULAR CELL

Repair of Strand Breaks by Homologous Recombination

(2013) M. Jasin et al.   Cold Spring Harbor Perspectives in Biology

DNA polymerases in nonhomologous end joining: Are there any benefits to standing out from the crowd?

(2012) Dale A. Ramsden et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Mouse models of DNA polymerases

(2012) Miriam R. Menezes et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

BRCT domain of DNA polymerase μ has DNA-binding activity and promotes the DNA polymerization activity

(2012) Takuro Matsumoto et al.   GENES TO CELLS

Role of recombination activating genes in the generation of antigen receptor diversity and beyond

(2012) Mayilaadumveettil Nishana et al.   IMMUNOLOGY

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

DNA-binding determinants promoting NHEJ by human Polµ

(2012) Maria Jose Martin et al.   NUCLEIC ACIDS RESEARCH

The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ

(2012) Rajendrakumar A. Gosavi et al.   NUCLEIC ACIDS RESEARCH

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

(2011) Zhiyong Mao et al.   CELL CYCLE

Molecular Insights into DNA Polymerase Deterrents for Ribonucleotide Insertion

(2011) Nisha A. Cavanaugh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse

(2011) J. T. Eppig et al.   NUCLEIC ACIDS RESEARCH

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Polymerases in Nonhomologous End Joining: Building a Bridge over Broken Chromosomes

(2010) Dale A. Ramsden   ANTIOXIDANTS & REDOX SIGNALING

Lack of DNA polymerase μ affects the kinetics of DNA double-strand break repair and impacts on cellular senescence

(2010) Romain Chayot et al.   DNA REPAIR

DNA Polymerases β and λ Mediate Overlapping and Independent Roles in Base Excision Repair in Mouse Embryonic Fibroblasts

(2010) Elena K. Braithwaite et al.   PLoS One

DNA polymerase Family X: Function, structure, and cellular roles

(2009) Jennifer Yamtich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Quantitation of cellular deoxynucleoside triphosphates

(2009) Paola Ferraro et al.   NUCLEIC ACIDS RESEARCH

Limited terminal transferase in human DNA polymerase   defines the required balance between accuracy and efficiency in NHEJ

(2009) P. Andrade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Hematopoiesis in Mice Lacking DNA Polymerase μ Is Due to Inefficient Double-Strand Break Repair

(2009) Daniel Lucas et al.   PLoS Genetics

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Distribution and roles of X-family DNA polymerases in eukaryotes

(2008) Yukinobu Uchiyama et al.   BIOCHIMIE

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

(2008) Scott D McCulloch et al.   CELL RESEARCH

A Role for DNA Polymerase   in the Emerging DJH Rearrangements of the Postgastrulation Mouse Embryo

(2008) B. Gozalbo-Lopez et al.   MOLECULAR AND CELLULAR BIOLOGY

End-bridging is required for pol μ to efficiently promote repair of noncomplementary ends by nonhomologous end joining

(2008) Bryan J. Davis et al.   NUCLEIC ACIDS RESEARCH

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

(2008) Nicole Bennardo et al.   PLoS Genetics