Pseudoginsenoside F11 ameliorates the dysfunction of the autophagy-lysosomal pathway by activating calcineurin-mediated TFEB nuclear translocation in neuron during permanent cerebral ischemia

Key Roles of MiT Transcription Factors in Innate Immunity and Inflammation

(2020) Javier E. Irazoqui   TRENDS IN IMMUNOLOGY

Deletion of Calcineurin in Schwann Cells Does Not Affect Developmental Myelination, But Reduces Autophagy and Delays Myelin Clearance after Peripheral Nerve Injury

(2020) Chelsey B. Reed et al.   JOURNAL OF NEUROSCIENCE

TFEB-mediated enhancement of the autophagy-lysosomal pathway dually modulates the process of amyloid β-protein generation in neurons

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Attenuating oxygen-glucose deprivation-caused autophagosome accumulation may be involved in sevoflurane postconditioning-induced protection in human neuron-like cells

(2019) Aobing Cheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pseudoginsenoside-F11 Protects against Transient Cerebral Ischemia Injury in Rats Involving Repressing Calcium Overload

(2019) Tianyu Zhang et al.   NEUROSCIENCE

A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

(2019) Ju‐Xian Song et al.   AGING CELL

Pseudoginsenoside-F11 improves long-term neurological function and promotes neurogenesis after transient cerebral ischemia in mice

(2019) Linlin Yuan et al.   NEUROCHEMISTRY INTERNATIONAL

Pseudoginsenoside-F11 Accelerates Microglial Phagocytosis of Myelin Debris and Attenuates Cerebral Ischemic Injury Through Complement Receptor 3

(2019) Yinglu Liu et al.   NEUROSCIENCE

Autophagy-A key pathway for cardiac health and longevity

(2018) B. P. Woodall et al.   Acta Physiologica

Emerging roles and regulation of MiT/TFE transcriptional factors

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The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

(2018) Rosa Puertollano et al.   EMBO JOURNAL

Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction

(2018) Sebastiano Sciarretta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities

(2018) Constanza J. Cortes et al.   NEUROBIOLOGY OF DISEASE

Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia

(2018) Yueyang Liu et al.   Autophagy

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration

(2018) Paola Rusmini et al.   Autophagy

Pseudoginsenoside-F11 alleviates cognitive deficits and Alzheimer’s disease-type pathologies in SAMP8 mice

(2018) Zhen Zhang et al.   PHARMACOLOGICAL RESEARCH

Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury

(2018) Hyo Jeong Kim et al.   Cell Death & Disease

Calcineurin signaling in the heart: The importance of time and place

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Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease

(2017) Tim E. Moors et al.   Molecular Neurodegeneration

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

(2017) Ismail Sergin et al.   Nature Communications

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

Evidence for the recruitment of autophagic vesicles in human brain after stroke

(2016) Tony Frugier et al.   NEUROCHEMISTRY INTERNATIONAL

The Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective

(2016) Heidi Martini-Stoica et al.   TRENDS IN NEUROSCIENCES

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein

(2015) Kiri Kilpatrick et al.   PLoS One

Neuroprotective Effect of Pseudoginsenoside-F11 on a Rat Model of Parkinson's Disease Induced by 6-Hydroxydopamine

(2013) Jian Yu Wang et al.   Evidence-based Complementary and Alternative Medicine

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anti-amnesic effect of pseudoginsenoside-F11 in two mouse models of Alzheimer's disease

(2013) Chun-Ming Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

TFEB-mediated autophagy rescues midbrain dopamine neurons from  -synuclein toxicity

(2013) M. Decressac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

(2013) Simina Grigoriu et al.   PLOS BIOLOGY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE