Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor

MyD88 signalling is critical in the development of pancreatic cancer cachexia

(2019) Xinxia Zhu et al.   Journal of Cachexia Sarcopenia and Muscle

The IMPACT study: early loss of skeletal muscle mass in advanced pancreatic cancer patients

(2019) Debora Basile et al.   Journal of Cachexia Sarcopenia and Muscle

Prognostic role of the neutrophil-to-lymphocyte ratio in pancreatic cancer: A meta-analysis containing 8252 patients

(2018) Yongping Zhou et al.   CLINICA CHIMICA ACTA

Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients

(2018) Erin E. Talbert et al.   Journal of Cachexia Sarcopenia and Muscle

Cancer-associated cachexia

(2018) Vickie E. Baracos et al.   Nature Reviews Disease Primers

Pancreas Cancer‐Associated Weight Loss

(2018) Andrew E. Hendifar et al.   ONCOLOGIST

Pancreatic adenocarcinoma up-regulated factor has oncogenic functions in oral squamous cell carcinoma

(2016) Tomonori Sasahira et al.   HISTOPATHOLOGY

Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer

(2016) Jinhoi Song et al.   Oncotarget

Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs

(2016) Rafael Barreto et al.   Oncotarget

Understanding cachexia as a cancer metabolism syndrome

(2016) P E Porporato   Oncogenesis

Inducible nitric oxide synthase (iNOS) in muscle wasting syndrome, sarcopenia, and cachexia

(2016) Derek T. Hall et al.   Aging-US

Muscle-specific E3 ubiquitin ligases are involved in muscle atrophy of cancer cachexia: An in vitro and in vivo study

(2015) LEI YUAN et al.   ONCOLOGY REPORTS

MAP3K11/GDF15 axis is a critical driver of cancer cachexia

(2015) Lorena Lerner et al.   Journal of Cachexia Sarcopenia and Muscle

Plasma growth differentiation factor 15 is associated with weight loss and mortality in cancer patients

(2015) Lorena Lerner et al.   Journal of Cachexia Sarcopenia and Muscle

Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1

(2014) Sue C. Bodine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A PAUF-neutralizing antibody targets both carcinoma and endothelial cells to impede pancreatic tumor progression and metastasis

(2014) Su Jin Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Inhibition of Protein Synthesis Alters Protein Degradation through Activation of Protein Kinase B (AKT)

(2013) Chun-Ling Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunomonitoring and prognostic relevance of neutrophils in clinical trials

(2013) Frede Donskov   SEMINARS IN CANCER BIOLOGY

Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology

(2012) Claudia A. Dumitru et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Pancreatic adenocarcinoma upregulated factor, a novel endothelial activator, promotes angiogenesis and vascular permeability

(2012) S J Kim et al.   ONCOGENE

Anti-inflammatory therapies in cancer cachexia

(2011) Josep M. Argilés et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase

(2011) Yangsoon Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of β-catenin, leading to a rapid proliferation of pancreatic cells

(2011) Il-Rae Cho et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy

(2011) Sarah A. Reed et al.   FASEB JOURNAL

Cancer Cachexia: Mechanisms and Clinical Implications

(2011) Claire L. Donohoe et al.   Gastroenterology Research and Practice

Elevated neutrophil to lymphocyte ratio predicts survival in advanced pancreatic cancer

(2010) Xin An et al.   BIOMARKERS

Anabolic and catabolic pathways regulating skeletal muscle mass

(2010) John J McCarthy et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation

(2010) H D Park et al.   ONCOGENE

Pancreatic cancerrelated cachexia: influence on metabolism and correlation to weight loss and pulmonary function

(2009) Jeannine Bachmann et al.   BMC CANCER

Pancreatic adenocarcinoma up-regulated factor (PAUF), a novel up-regulated secretory protein in pancreatic ductal adenocarcinoma

(2009) Sun A. Kim et al.   CANCER SCIENCE

PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression

(2009) Y Lee et al.   ONCOGENE

Mechanisms of Cancer Cachexia

(2009) Michael J. Tisdale   PHYSIOLOGICAL REVIEWS

Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

(2008) Carla MM Prado et al.   LANCET ONCOLOGY