Methyl palmitate protects heart against ischemia/reperfusion-induced injury through G-protein coupled receptor 40-mediated activation of the PI3K/AKT pathway

PI3K isoforms in cell signalling and vesicle trafficking

(2019) Benoit Bilanges et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells

(2019) Ryota Usui et al.   Scientific Reports

Free Fatty Acid Receptor G-protein–coupled Receptor 40 Mediates Lipid Emulsion-induced Cardioprotection

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Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms

(2018) John R. Petrie et al.   CANADIAN JOURNAL OF CARDIOLOGY

Intermittent hypoxia-generated ROS contributes to intracellular zinc regulation that limits ischemia/reperfusion injury in adult rat cardiomyocyte

(2018) Chih-Feng Lien et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PI3k/AKT signaling pathway: Erythropoiesis and beyond

(2018) Mahjoobeh Jafari et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α

(2018) Li Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Effect of Methyl Palmitate on the Formation of Epidural Fibrosis in an Experimental Epidural Fibrosis Model

(2017) Zahir Kizilay et al.   JOURNAL OF INVESTIGATIVE SURGERY

Osmotin Protects H9c2 Cells from Simulated Ischemia-Reperfusion Injury through AdipoR1/PI3K/AKT Signaling Pathway

(2017) Jianhua Liu et al.   Frontiers in Physiology

PI3K/AKT signaling mediated by G protein-coupled receptors is involved in neurodegenerative Parkinson's disease (Review)

(2016) Noriko Nakano et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Heart regeneration after myocardial infarction using synthetic biomaterials

(2015) S. Pascual-Gil et al.   JOURNAL OF CONTROLLED RELEASE

Molecular mechanisms underlying oxytocin-induced cardiomyocyte protection from simulated ischemia–reperfusion

(2015) Araceli Gonzalez-Reyes et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Protective effects of methyl palmitate against silica-induced pulmonary fibrosis in rats

(2013) Maha H. Sharawy et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial

(2012) Charles F Burant et al.   LANCET

Involvement of the long-chain fatty acid receptor GPR40 as a novel pain regulatory system

(2011) Kazuo Nakamoto et al.   BRAIN RESEARCH

Role of Perivascular Adipose Tissue–Derived Methyl Palmitate in Vascular Tone Regulation and Pathogenesis of Hypertension

(2011) Yuan-Chieh Lee et al.   CIRCULATION

Anti-inflammatory and antifibrotic effects of methyl palmitate

(2011) Ebtehal El-Demerdash   TOXICOLOGY AND APPLIED PHARMACOLOGY

Cardiac conditioning: a review of evolving strategies to reduce ischaemia-reperfusion injury

(2010) R. K. Kharbanda   HEART

PI3Kγ Protects from Myocardial Ischemia and Reperfusion Injury through a Kinase-Independent Pathway

(2010) Bernhard J. Haubner et al.   PLoS One

Activation of Akt/GSK-3β signaling pathway is involved in intermedin1–53 protection against myocardial apoptosis induced by ischemia/reperfusion

(2009) Jun-Qiu Song et al.   APOPTOSIS

Overexpression of GPR40 in Pancreatic  -Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice

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