Targeting autophagy to modulate hepatic ischemia/reperfusion injury: A comparative study between octreotide and melatonin as autophagy modulators through AMPK/PI3K/AKT/mTOR/ULK1 and Keap1/Nrf2 signaling pathways in rats

Octreotide and melatonin alleviate inflammasome-induced pyroptosis through inhibition of TLR4-NF-κB-NLRP3 pathway in hepatic ischemia/reperfusion injury

(2020) Alaa El-Din El-Sayed El-Sisi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ischemia Reperfusion Injury in Liver Transplantation: Cellular and Molecular mechanisms

(2019) Wasim A. Dar et al.   LIVER INTERNATIONAL

Octreotide protects against hepatic ischemia/reperfusion injury via HO-1-mediated autophagy

(2018) Shuangfa Zou et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Immunohistochemistry of Pulmonary Biomarkers: A Perspective From Members of the Pulmonary Pathology Society

(2018) Erik Thunnissen et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

The mammalian ULK1 complex and autophagy initiation

(2017) Maria Zachari et al.   Essays in Biochemistry

Effect of cardamonin on hepatic ischemia reperfusion induced in rats: Role of nitric oxide

(2017) Yara Atef et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

IL-12 induces autophagy in human breast cancer cells through AMPK and the PI3K/Akt pathway

(2017) Yan Lin et al.   Molecular Medicine Reports

Octreotide Ameliorates Renal Ischemia/Reperfusion Injury via Antioxidation and Anti-inflammation

(2017) Z. Xu et al.   TRANSPLANTATION PROCEEDINGS

The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy

(2017) Dongwei Xu et al.   Cell Death & Disease

The frequency and clinical impact of HER2 alterations in lung adenocarcinoma

(2017) Eun Kyung Kim et al.   PLoS One

Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die

(2016) Jee-Yeon Hwang et al.   CELL DEATH AND DIFFERENTIATION

Regulation of inflammasomes by autophagy

(2016) Tatsuya Saitoh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Effects of melatonin on liver function and lipid peroxidation in a rat model of hepatic ischemia/reperfusion injury

(2016) WEN-SHENG DENG et al.   Experimental and Therapeutic Medicine

Advances in Autophagy Regulatory Mechanisms

(2016) Laura Gallagher et al.   Cells

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

(2015) Weili Tian et al.   FEBS LETTERS

p62 links autophagy and Nrf2 signaling

(2015) Tao Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox regulation of autophagy in healthy brain and neurodegeneration

(2015) Kenneth Hensley et al.   NEUROBIOLOGY OF DISEASE

Octreotide Protects the Mouse Retina against Ischemic Reperfusion Injury through Regulation of Antioxidation and Activation of NF-κB

(2015) Jun Wang et al.   Oxidative Medicine and Cellular Longevity

Protective role of adiponectin in a rat model of intestinal ischemia reperfusion injury

(2015) Xu-Hui Liu   WORLD JOURNAL OF GASTROENTEROLOGY

Autophagy and human disease: emerging themes

(2014) Jaime L Schneider et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Modulation of autophagy for the treatment of liver diseases

(2014) Jordi Gracia-Sancho et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Sevoflurane postconditioning attenuates cerebral ischemia-reperfusion injury via protein kinase B/nuclear factor-erythroid 2-related factor 2 pathway activation

(2014) Bo Li et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Sildenafil Attenuates Hepatocellular Injury after Liver Ischemia Reperfusion in Rats: A Preliminary Study

(2014) Spyridon Savvanis et al.   Oxidative Medicine and Cellular Longevity

Tumor Suppression and Promotion by Autophagy

(2014) Yenniffer Ávalos et al.   Biomed Research International

Nrf2 Activation Protects the Liver From Ischemia/Reperfusion Injury in Mice

(2013) Kazuhiro Kudoh et al.   ANNALS OF SURGERY

Role of AMP-Activated Protein Kinase in Ferritin H Gene Expression by Resveratrol in Human T Cells

(2013) Kenta Iwasaki et al.   BIOCHEMISTRY

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway

(2013) Dong-Mei Zhang et al.   CARCINOGENESIS

KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants

(2013) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

AMPK synergizes with the combined treatment of 1′-acetoxychavicol acetate and sodium butyrate to upregulate phase II detoxifying enzyme activities

(2013) Keisuke Yaku et al.   MOLECULAR NUTRITION & FOOD RESEARCH

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

The Effect of Octreotide on Hepatic Ischemia-Reperfusion Injury in a Rabbit Model

(2013) J. Yang et al.   TRANSPLANTATION PROCEEDINGS

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

The role of AMPK/mTOR/S6K1 signaling axis in mediating the physiological process of exercise-induced insulin sensitization in skeletal muscle of C57BL/6 mice

(2012) Xiaolei Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion

(2012) Jung-Woo Kang et al.   JOURNAL OF PINEAL RESEARCH

Effects of AMPK activation and combined treatment with AMPK activators and somatostatin on hormone secretion and cell growth in cultured GH-secreting pituitary tumor cells

(2012) Giovanni Tulipano et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Keap1 degradation by autophagy for the maintenance of redox homeostasis

(2012) K. Taguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Suppresses Age-Dependent Ischemia and Reperfusion Injury in Livers of Mice

(2011) Jin–Hee Wang et al.   GASTROENTEROLOGY

Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway

(2011) Jung-Woo Kang et al.   JOURNAL OF PINEAL RESEARCH

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Structural Basis of Atg8 Activation by a Homodimeric E1, Atg7

(2011) Nobuo N. Noda et al.   MOLECULAR CELL

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice

(2010) X. Kong et al.   JOURNAL OF IMMUNOLOGY

Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes

(2010) Pil-Jae Kong et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

(2009) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species

(2009) Scott A. Reisman et al.   TOXICOLOGICAL SCIENCES

Hydrogen peroxide mobilizes Ca2+ through two distinct mechanisms in rat hepatocytes

(2008) Hirohiko Sato et al.   ACTA PHARMACOLOGICA SINICA

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

(2008) Jae-Sung Kim et al.   HEPATOLOGY

Established and potential therapeutic applications of octreotide in palliative care

(2008) Eric E. Prommer   SUPPORTIVE CARE IN CANCER