Powder suspensions in non-aqueous vehicles for delivery of therapeutic proteins

Test Models for the Evaluation of Immunogenicity of Protein Aggregates

(2019) Teresa Kraus et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Characterization of spray dried powders with nucleic acid-containing PEI nanoparticles

(2019) Tobias W.M. Keil et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Parenteral protein formulations: An overview of approved products within the European Union

(2018) V. Gervasi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Pregnancy outcomes from more than 1,800 in vitro fertilization cycles with the use of 24-chromosome single-nucleotide polymorphism–based preimplantation genetic testing for aneuploidy

(2018) Alexander L. Simon et al.   FERTILITY AND STERILITY

A pilot study using a novel pyrotechnically driven prototype applicator for epidermal powder immunization in piglets

(2018) Julia Engert et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Notorious but not understood: How liquid-air interfacial stress triggers protein aggregation

(2018) Ellen Koepf et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Drying Technologies for the Stability and Bioavailability of Biopharmaceuticals

(2018) Fakhrossadat Emami et al.   Pharmaceutics

Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches

(2018) Ahmad Ziaee et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

How sugars protect proteins in the solid state and during drying (review): Mechanisms of stabilization in relation to stress conditions

(2017) Maarten A. Mensink et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Milling solid proteins to enhance activity after melt-encapsulation

(2017) Parker W. Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Density, viscosity, surface tension, and molar volume of propylene glycol + water mixtures from 293 to 323 K and correlations by the Jouyban–Acree model

(2017) Ibrahim S. Khattab et al.   Arabian Journal of Chemistry

THPdb: Database of FDA-approved peptide and protein therapeutics

(2017) Salman Sadullah Usmani et al.   PLoS One

Study of stability and biophysical characterization of ranibizumab and aflibercept

(2016) M.R. Moreno et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Subcutaneous Injection Volume of Biopharmaceuticals—Pushing the Boundaries

(2016) Roman Mathaes et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

An overview of FDA-approved biologics medicines

(2015) Michael S. Kinch   DRUG DISCOVERY TODAY

Arrhenius activation energy of damage to catalase during spray-drying

(2015) Joachim Schaefer et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Stability of collapse lyophilized influenza vaccine formulations

(2015) Cihad Anamur et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Evaluation of pharmacokinetic properties and anaesthetic effects of propofol in a new perfluorohexyloctane (F6H8) emulsion in rats – A comparative study

(2015) Charalambos Tsagogiorgas et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Pre-filled syringes: a review of the history, manufacturing and challenges

(2015) Gregory Sacha et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules

(2014) Bibi F. Choonara et al.   BIOTECHNOLOGY ADVANCES

Semifluorinated alkanes as a liquid drug carrier system for topical ocular drug delivery

(2014) R.M. Dutescu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Rheological characterization and injection forces of concentrated protein formulations: An alternative predictive model for non-Newtonian solutions

(2014) Andrea Allmendinger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Biopharmaceutical formulations for pre-filled delivery devices

(2013) Jan Jezek et al.   Expert Opinion on Drug Delivery

Toward intradermal vaccination: preparation of powder formulations by collapse freeze-drying

(2013) Elsa E. Etzl et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Non-Aqueous Suspensions of Antibodies are Much Less Viscous Than Equally Concentrated Aqueous Solutions

(2013) Charudharshini Srinivasan et al.   PHARMACEUTICAL RESEARCH

Shear rheology of hard-sphere, dispersed, and aggregated suspensions, and filler-matrix composites

(2012) Diego B. Genovese   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Systematic Investigation of the Effect of Lyophilizate Collapse on Pharmaceutically Relevant Proteins, Part 2: Stability During Storage at Elevated Temperatures

(2012) Kathrin Schersch et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Investigating High-Concentration Monoclonal Antibody Powder Suspension in Nonaqueous Suspension Vehicles for Subcutaneous Injection

(2012) Mayumi Bowen et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Formation of Reactive Impurities in Aqueous and Neat Polyethylene Glycol 400 and Effects of Antioxidants and Oxidation Inducers

(2012) Jeffrey N. Hemenway et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Role of Polysorbate 80 and HPβCD at the Air-Water Interface of IgG Solutions

(2012) Tim Serno et al.   PHARMACEUTICAL RESEARCH

Injectability Evaluation: An Open Issue

(2011) Francesco Cilurzo et al.   AAPS PHARMSCITECH

Free Radical Oxidation of Polyunsaturated Lipids: New Mechanistic Insights and the Development of Peroxyl Radical Clocks

(2011) Derek A. Pratt et al.   ACCOUNTS OF CHEMICAL RESEARCH

The effect of a new syringe design on the ability of rheumatoid arthritis patients to inject a biological medication

(2011) Ali Sheikhzadeh et al.   APPLIED ERGONOMICS

Rheological and syringeability properties of highly concentrated human polyclonal immunoglobulin solutions

(2010) V. Burckbuchler et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Semifluorinated alkanes – A new class of excipients suitable for pulmonary drug delivery

(2010) C. Tsagogiorgas et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Chemistry, Physical Chemistry, and Uses of Molecular Fluorocarbon−Hydrocarbon Diblocks, Triblocks, and Related CompoundsUnique “Apolar” Components for Self-Assembled Colloid and Interface Engineering

(2009) Marie Pierre Krafft et al.   CHEMICAL REVIEWS

Mechanisms of protein stabilization in the solid state

(2009) Liuquan (Lucy) Chang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution

(2009) Renuka Thirumangalathu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Low Viscosity Highly Concentrated Injectable Nonaqueous Suspensions of Lysozyme Microparticles

(2009) Maria A. Miller et al.   LANGMUIR

Injectability of biodegradable in situ forming microparticle systems (ISM)

(2008) W. Rungseevijitprapa et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Nature and consequences of protein–protein interactions in high protein concentration solutions

(2008) Atul Saluja et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Reversible Self-Association of a Concentrated Monoclonal Antibody Solution Mediated by Fab–Fab Interaction That Impacts Solution Viscosity

(2008) Sonoko Kanai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Liquid high concentration IgG1 antibody formulations by precipitation

(2008) Susanne Matheus et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Protein aggregation: Pathways, induction factors and analysis

(2008) Hanns-Christian Mahler et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Stabilization of IgG by supercritical fluid drying: Optimization of formulation and process parameters

(2007) Nataša Jovanović et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Stable sugar-based protein formulations by supercritical fluid drying

(2007) Nataša Jovanović et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS