A Phase II study of autologous mesenchymal stromal cells and c‐kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN CONCERT‐HF trial

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Inflammation in Heart Failure

(2020) Sean P. Murphy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Extracellular Matrix in Ischemic Heart Disease, Part 4/4

(2020) Nikolaos G. Frangogiannis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

After the Storm: An Objective Appraisal of the Efficacy of c-kit+ Cardiac Progenitor Cells in Preclinical Models of Heart Disease

(2020) Roberto Bolli et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure

(2019) Kenneth M. Borow et al.   CIRCULATION RESEARCH

Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit+Cardiac Stem Cells As Regenerative Therapy for Heart Failure)Novelty and Significance

(2018) Roberto Bolli et al.   CIRCULATION RESEARCH

New Paradigms in Cell Therapy

(2018) Marcin Wysoczynski et al.   CIRCULATION RESEARCH

Clinical Studies of Cell Therapy in Cardiovascular Medicine

(2018) Monisha N. Banerjee et al.   CIRCULATION RESEARCH

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials

(2018) Karen A. Hicks et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Global position paper on cardiovascular regenerative medicine

(2017) Francisco Fernández-Avilés et al.   EUROPEAN HEART JOURNAL

The consensus of the Task Force of the European Society of Cardiology concerning the clinical investigation of the use of autologous adult stem cells for the treatment of acute myocardial infarction and heart failure: update 2016

(2017) Anthony Mathur et al.   EUROPEAN HEART JOURNAL

C-Kit Positive Cardiac Stem Cells and Bone Marrow–Derived Mesenchymal Stem Cells Synergistically Enhance Angiogenesis and Improve Cardiac Function After Myocardial Infarction in a Paracrine Manner

(2017) Luer Bao et al.   JOURNAL OF CARDIAC FAILURE

Effect of Bone Marrow–Derived Mononuclear Cell Treatment, Early or Late After Acute Myocardial InfarctionNovelty and Significance

(2016) Daniel Sürder et al.   CIRCULATION RESEARCH

Long-Term Outcome of Administration of c-kitPOSCardiac Progenitor Cells After Acute Myocardial InfarctionNovelty and Significance

(2016) Xian-Liang Tang et al.   CIRCULATION RESEARCH

Repeated Administrations of Cardiac Progenitor Cells Are Markedly More Effective Than a Single AdministrationNovelty and Significance

(2016) Yukichi Tokita et al.   CIRCULATION RESEARCH

Cardiac Stem Cell Treatment in Myocardial InfarctionNovelty and Significance

(2016) Peter Paul Zwetsloot et al.   CIRCULATION RESEARCH

Ixmyelocel-T for patients with ischaemic heart failure: a prospective randomised double-blind trial

(2016) Amit N Patel et al.   LANCET

“String Theory” of c-kitposCardiac Cells

(2015) Matthew C.L. Keith et al.   CIRCULATION RESEARCH

A Phase II Dose-Escalation Study of Allogeneic Mesenchymal Precursor Cells in Patients With Ischemic or Nonischemic Heart FailureNovelty and Significance

(2015) Emerson C. Perin et al.   CIRCULATION RESEARCH

Use of Mesenchymal Stem Cells for Therapy of Cardiac Disease

(2015) V. Karantalis et al.   CIRCULATION RESEARCH

Bone marrow-derived mesenchymal stromal cell treatment in patients with severe ischaemic heart failure: a randomized placebo-controlled trial (MSC-HF trial)

(2015) Anders Bruun Mathiasen et al.   EUROPEAN HEART JOURNAL

Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy

(2015) Vasileios Karantalis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials

(2015) Karen A. Hicks et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Safety and Efficacy of Ixmyelocel-T

(2014) Timothy D. Henry et al.   CIRCULATION RESEARCH

Autologous Mesenchymal Stem Cells Produce Concordant Improvements in Regional Function, Tissue Perfusion, and Fibrotic Burden When Administered to Patients Undergoing Coronary Artery Bypass Grafting

(2014) Vasileios Karantalis et al.   CIRCULATION RESEARCH

c-kit+ cells minimally contribute cardiomyocytes to the heart

(2014) Jop H. van Berlo et al.   NATURE

c-kit+ Cardiac Stem Cells Alleviate Post-Myocardial Infarction Left Ventricular Dysfunction Despite Poor Engraftment and Negligible Retention in the Recipient Heart

(2014) Kyung U. Hong et al.   PLoS One

Phase II Clinical Research Design in Cardiology

(2013) Joshua M. Hare et al.   CIRCULATION

Cell Therapy for Heart Failure

(2013) Santosh K. Sanganalmath et al.   CIRCULATION RESEARCH

Transendocardial Mesenchymal Stem Cells and Mononuclear Bone Marrow Cells for Ischemic Cardiomyopathy

(2013) Alan W. Heldman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Enhanced Effect of Combining Human Cardiac Stem Cells and Bone Marrow Mesenchymal Stem Cells to Reduce Infarct Size and to Restore Cardiac Function After Myocardial Infarction

(2012) Adam R. Williams et al.   CIRCULATION

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction

(2012) Jay H. Traverse et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparison of Allogeneic vs Autologous Bone Marrow–Derived Mesenchymal Stem Cells Delivered by Transendocardial Injection in Patients With Ischemic Cardiomyopathy

(2012) Joshua M. Hare et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Intramyocardial Stem Cell Injection in Patients With Ischemic Cardiomyopathy

(2011) Adam R. Williams et al.   CIRCULATION RESEARCH

Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function

(2011) Jay H. Traverse   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation

(2010) Konstantinos E. Hatzistergos et al.   CIRCULATION RESEARCH

Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy

(2009) K. H. Schuleri et al.   EUROPEAN HEART JOURNAL

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction

(2009) Joshua M. Hare et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity

(2009) H. C. Quevedo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early improvement in cardiac tissue perfusion due to mesenchymal stem cells

(2008) Karl H. Schuleri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY