Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure
Authors
Keywords
-
Journal
CIRCULATION RESEARCH
Volume 125, Issue 3, Pages 265-281
Publisher
Ovid Technologies (Wolters Kluwer Health)
Online
2019-07-19
DOI
10.1161/circresaha.119.314951
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF
- (2019) Melissa A. Daubert et al. JACC-Heart Failure
- A Fully Magnetically Levitated Left Ventricular Assist Device — Final Report
- (2019) Mandeep R. Mehra et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure
- (2019) Terrence M. Yau et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- OPTN/SRTR 2017 Annual Data Report: Heart
- (2019) M. Colvin et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Use of Ventricular Assist Devices and Heart Transplantation for Advanced Heart Failure
- (2019) Leslie Miller et al. CIRCULATION RESEARCH
- Leveraging Signaling Pathways to Treat Heart Failure With Reduced Ejection Fraction
- (2019) Miguel Pinilla-Vera et al. CIRCULATION RESEARCH
- Medical Therapy for Heart Failure Caused by Ischemic Heart Disease
- (2019) Islam Y. Elgendy et al. CIRCULATION RESEARCH
- The Medical and Device-Related Treatment of Heart Failure
- (2019) James T. Willerson CIRCULATION RESEARCH
- Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association
- (2018) Emelia J. Benjamin et al. CIRCULATION
- The human heart contains distinct macrophage subsets with divergent origins and functions
- (2018) Geetika Bajpai et al. NATURE MEDICINE
- Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure
- (2018) Mandeep R. Mehra et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adaptive design clinical trials: a review of the literature and ClinicalTrials.gov
- (2018) Laura E Bothwell et al. BMJ Open
- Established and Emerging Roles of Biomarkers in Heart Failure
- (2018) Nasrien E. Ibrahim et al. CIRCULATION RESEARCH
- Left ventricular assist device therapy in advanced heart failure: patient selection and outcomes
- (2017) Finn Gustafsson et al. EUROPEAN JOURNAL OF HEART FAILURE
- Echocardiographic Predictors of Long-Term Survival in Patients Undergoing Cardiac Resynchronization Therapy: What Is the Optimal Metric?
- (2017) JOHN RICKARD et al. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- Left Ventricular Assist Devices for Lifelong Support
- (2017) Sean P. Pinney et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Intrapericardial Left Ventricular Assist Device for Advanced Heart Failure
- (2017) Joseph G. Rogers et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Fully Magnetically Levitated Circulatory Pump for Advanced Heart Failure
- (2017) Mandeep R. Mehra et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immunoselected STRO-3+ mesenchymal precursor cells reduce inflammation and improve clinical outcomes in a large animal model of monoarthritis
- (2017) Anwar Abdalmula et al. Stem Cell Research & Therapy
- Macrophages in the Remodeling Failing Heart
- (2016) Bijun Chen et al. CIRCULATION RESEARCH
- The Human Microcirculation
- (2016) David D. Gutterman et al. CIRCULATION RESEARCH
- Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency
- (2016) Stefan D. Anker et al. EUROPEAN JOURNAL OF HEART FAILURE
- The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure
- (2016) Alexandros Briasoulis et al. HEART FAILURE REVIEWS
- The medical and socioeconomic burden of heart failure: A comparative delineation with cancer
- (2016) Dimitrios Farmakis et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- New therapy, new challenges: The effects of long-term continuous flow left ventricular assist device on inflammation
- (2016) Liza Grosman-Rimon et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Prognostic value of angiopoietin-2 in patients with chronic heart failure
- (2016) Ermanno Eleuteri et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- 2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure: An Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure
- (2016) Clyde W. Yancy et al. JOURNAL OF CARDIAC FAILURE
- Monocyte and macrophage contributions to cardiac remodeling
- (2016) Maarten Hulsmans et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Inflammation as a Driver of Adverse Left Ventricular Remodeling After Acute Myocardial Infarction
- (2016) Peter C. Westman et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Clinical Implications of Complete Left-Sided Reverse Remodeling With Cardiac Resynchronization Therapy
- (2016) Andrew Mathias et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Precision medicine in cardiology
- (2016) Elliott M. Antman et al. Nature Reviews Cardiology
- Analysis of recurrent events with an associated informative dropout time: Application of the joint frailty model
- (2016) Jennifer K. Rogers et al. STATISTICS IN MEDICINE
- T1-Mapping and Outcome in Nonischemic Cardiomyopathy
- (2016) Valentina O. Puntmann et al. JACC-Cardiovascular Imaging
- 3D echocardiographic reference ranges for normal left ventricular volumes and strain: results from the EACVI NORRE study
- (2016) Anne Bernard et al. European Heart Journal-Cardiovascular Imaging
- Full Expression of Cardiomyopathy Is Partly Dependent on B‐Cells: A Pathway That Involves Cytokine Activation, Immunoglobulin Deposition, and Activation of Apoptosis
- (2016) Andrea M. Cordero‐Reyes et al. Journal of the American Heart Association
- Bleeding in continuous flow left ventricular assist device recipients: an acquired vasculopathy?
- (2016) Snehal R. Patel et al. Journal of Thoracic Disease
- Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study
- (2016) David K. Packham et al. EBioMedicine
- Biologic plausibility, cellular effects, and molecular mechanisms of eicosapentaenoic acid (EPA) in atherosclerosis
- (2015) Kenneth M. Borow et al. ATHEROSCLEROSIS
- Longitudinal Assessment of Inflammation in Recipients of Continuous-Flow Left Ventricular Assist Devices
- (2015) Liza Grosman-Rimon et al. CANADIAN JOURNAL OF CARDIOLOGY
- Attenuation in Peripheral Endothelial Function After Continuous Flow Left Ventricular Assist Device Therapy Is Associated With Cardiovascular Adverse Events
- (2015) Tal Hasin et al. CIRCULATION JOURNAL
- Prognostic Significance of Peripheral Microvascular Endothelial Dysfunction in Heart Failure With Reduced Left Ventricular Ejection Fraction
- (2015) Koichiro Fujisue et al. CIRCULATION JOURNAL
- A Phase II Dose-Escalation Study of Allogeneic Mesenchymal Precursor Cells in Patients With Ischemic or Nonischemic Heart FailureNovelty and Significance
- (2015) Emerson C. Perin et al. CIRCULATION RESEARCH
- Innate Immunity and the Failing Heart
- (2015) Douglas L. Mann CIRCULATION RESEARCH
- Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled, Dose-Escalation Safety and Tolerability Pilot Study
- (2015) Jay S. Skyler et al. DIABETES CARE
- Cardiac endothelium–myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction
- (2015) Shir Lynn Lim et al. EUROPEAN HEART JOURNAL
- Beyond ejection fraction: an integrative approach for assessment of cardiac structure and function in heart failure
- (2015) Maja Cikes et al. EUROPEAN HEART JOURNAL
- The effect of reverse remodeling on long-term survival in mildly symptomatic patients with heart failure receiving cardiac resynchronization therapy: Results of the REVERSE study
- (2015) Michael R. Gold et al. HEART RHYTHM
- Cardioprotective Effects of Mesenchymal Precursor Cells in Patients With Advanced Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction
- (2015) Emerson C. Perin et al. JOURNAL OF CARDIAC FAILURE
- Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging
- (2015) Roberto M. Lang et al. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
- Effect of Mesenchymal Precursor Cells on the Systemic Inflammatory Response and Endothelial Dysfunction in an Ovine Model of Collagen-Induced Arthritis
- (2015) Laura M. Dooley et al. PLoS One
- Mesenchymal Precursor Cells as Adjunctive Therapy in Recipients of Contemporary Left Ventricular Assist Devices
- (2014) Deborah D. Ascheim et al. CIRCULATION
- A Reevaluation of the Costs of Heart Failure and Its Implications for Allocation of Health Resources in the United States
- (2014) Jeff Voigt et al. CLINICAL CARDIOLOGY
- Cardiac Macrophages: How to Mend a Broken Heart
- (2014) Heather B. Cohen et al. IMMUNITY
- The inflammatory response in myocardial injury, repair and remodelling
- (2014) Nikolaos G. Frangogiannis Nature Reviews Cardiology
- Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
- (2014) John J.V. McMurray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Angiopoietin-1 regulates microvascular reactivity and protects the microcirculation during acute endothelial dysfunction: Role of eNOS and VE-cadherin
- (2014) Alessio Alfieri et al. PHARMACOLOGICAL RESEARCH
- Echocardiographic reference ranges for normal cardiac chamber size: results from the NORRE study
- (2014) S. Kou et al. European Heart Journal-Cardiovascular Imaging
- Design of a Phase 2b Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Advanced Heart Failure
- (2014) Barry Greenberg et al. JACC-Heart Failure
- How can we cure a heart “in flame”? A translational view on inflammation in heart failure
- (2013) Ulrich Hofmann et al. BASIC RESEARCH IN CARDIOLOGY
- Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction
- (2013) Barry A. Borlaug CIRCULATION JOURNAL
- Intracoronary Infusion of Allogeneic Mesenchymal Precursor Cells Directly After Experimental Acute Myocardial Infarction Reduces Infarct Size, Abrogates Adverse Remodeling, and Improves Cardiac Function
- (2013) Jaco H. Houtgraaf et al. CIRCULATION RESEARCH
- Epidemiology of Heart Failure
- (2013) Véronique L. Roger CIRCULATION RESEARCH
- Forecasting the Impact of Heart Failure in the United States
- (2013) Paul A. Heidenreich et al. Circulation-Heart Failure
- Heart failure and anti tumor necrosis factor-alpha in systemic chronic inflammatory diseases
- (2013) Emanuele Sinagra et al. European Journal of Internal Medicine
- Strategies and Opportunities for Drug Development in Heart Failure
- (2013) Javed Butler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Association of Fibrosis With Mortality and Sudden Cardiac Death in Patients With Nonischemic Dilated Cardiomyopathy
- (2013) Ankur Gulati et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- VON WILLEBRAND FACTOR, ANGIODYSPLASIA AND ANGIOGENESIS
- (2013) Anna M. Randi et al. Mediterranean Journal of Hematology and Infectious Diseases
- Angiopoietin-2 Functions as a Tie2 Agonist in Tumor Models, Where It Limits the Effects of VEGF Inhibition
- (2012) C. Daly et al. CANCER RESEARCH
- Catheter-Based Endomyocardial Delivery of Mesenchymal Precursor Cells Using 3D Echo Guidance Improves Cardiac Function in a Chronic Myocardial Injury Ovine Model
- (2012) Yanping Cheng et al. CELL TRANSPLANTATION
- Eplerenone in Patients With Systolic Heart Failure and Mild Symptoms
- (2012) Jennifer K. Rogers et al. CIRCULATION
- Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies
- (2012) Stuart J. Pocock et al. EUROPEAN HEART JOURNAL
- Soluble guanylate cyclase: a potential therapeutic target for heart failure
- (2012) Mihai Gheorghiade et al. HEART FAILURE REVIEWS
- Endothelial Dysfunction, Arterial Stiffness, and Heart Failure
- (2012) Catherine N. Marti et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Effects of selective heart rate reduction with ivabradine on left ventricular remodelling and function: results from the SHIFT echocardiography substudy
- (2011) Jean-Claude Tardif et al. EUROPEAN HEART JOURNAL
- Stepwise increase of angiopoietin-2 serum levels is related to haemodynamic and functional impairment in stable chronic heart failure
- (2011) Ermanno Eleuteri et al. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION
- Reverse Remodeling and the Risk of Ventricular Tachyarrhythmias in the MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy)
- (2011) Alon Barsheshet et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Left Ventricular Remodeling in Heart Failure
- (2011) Marvin A. Konstam et al. JACC-Cardiovascular Imaging
- Cardiac remodelling and myocardial recovery: lost in translation?
- (2010) Douglas L. Mann et al. EUROPEAN JOURNAL OF HEART FAILURE
- Myocardial remodeling, an overview
- (2010) Dennis V. Cokkinos et al. HEART FAILURE REVIEWS
- Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities
- (2010) Jason J. Gajarsa et al. HEART FAILURE REVIEWS
- The impact of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in mild heart failure
- (2010) Michael R. Gold et al. HEART RHYTHM
- Reparative Effects of Allogeneic Mesenchymal Precursor Cells Delivered Transendocardially in Experimental Nonischemic Cardiomyopathy
- (2010) Peter J. Psaltis et al. JACC-Cardiovascular Interventions
- Therapeutic effects of human STRO-3-selected mesenchymal precursor cells and their soluble factors in experimental myocardial ischemia
- (2010) Fiona See et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Quantitative Evaluation of Drug or Device Effects on Ventricular Remodeling as Predictors of Therapeutic Effects on Mortality in Patients With Heart Failure and Reduced Ejection Fraction
- (2010) Daniel G. Kramer et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study
- (2010) Karl Swedberg et al. LANCET
- TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure
- (2010) Petra Kleinbongard et al. PHARMACOLOGY & THERAPEUTICS
- The Paradoxical Role of Inflammation in Cardiac Repair and Regeneration
- (2010) Bingbing Jiang et al. Journal of Cardiovascular Translational Research
- Allogeneic Mesenchymal Precursor Cell Therapy to Limit Remodeling After Myocardial Infarction: The Effect of Cell Dosage
- (2009) Hirotsugu Hamamoto et al. ANNALS OF THORACIC SURGERY
- Neuroendocrine Effects on the Heart and Targets for Therapeutic Manipulation in Heart Failure
- (2009) Parminder S. Chaggar et al. Cardiovascular Therapeutics
- Cardiac Resynchronization Therapy in Dyssynchronous Heart Failure
- (2009) Marc Vanderheyden et al. CIRCULATION
- Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials
- (2009) M. Metra et al. EUROPEAN HEART JOURNAL
- Vascular endothelial function predicts mortality risk in patients with advanced ischaemic chronic heart failure†
- (2009) Michael Shechter et al. EUROPEAN JOURNAL OF HEART FAILURE
- Long-Term Prognosis After Cardiac Resynchronization Therapy Is Related to the Extent of Left Ventricular Reverse Remodeling at Midterm Follow-Up
- (2009) Claudia Ypenburg et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The Sympathetic Nervous System in Heart Failure
- (2009) Filippos Triposkiadis et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Cardiac-Resynchronization Therapy for the Prevention of Heart-Failure Events
- (2009) Arthur J. Moss et al. NEW ENGLAND JOURNAL OF MEDICINE
- Assessment and Key Targets for Therapy in the Post-Myocardial Infarction Patient with Left Ventricular Dysfunction
- (2008) James D. Flaherty et al. AMERICAN JOURNAL OF CARDIOLOGY
- Intracellular devastation in heart failure
- (2008) Federica del Monte et al. HEART FAILURE REVIEWS
- Molecular Remodeling in Human Heart Failure⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.
- (2008) Thomas P. Cappola JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Prognostic Value of Left Ventricular End-Systolic Volume Index as a Predictor of Heart Failure Hospitalization in Stable Coronary Artery Disease: Data from the Heart and Soul Study
- (2008) David D. McManus et al. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
- Biomarkers in Heart Failure
- (2008) Eugene Braunwald NEW ENGLAND JOURNAL OF MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started