Halomonas as a chassis

Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis

(2021) Xiao-Ran Jiang et al.   Nature Communications

In-situ generation of large numbers of genetic combinations for metabolic reprogramming via CRISPR-guided base editing

(2021) Yu Wang et al.   Nature Communications

Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha

(2021) Jiaoqi Gao et al.   iScience

SEVA 3.0: an update of the Standard European Vector Architecture for enabling portability of genetic constructs among diverse bacterial hosts

(2020) Esteban Martínez-García et al.   NUCLEIC ACIDS RESEARCH

Metabolic Pathway Construction and Optimization of Escherichia coli for High-Level Ectoine Production

(2020) Jun Chen et al.   CURRENT MICROBIOLOGY

Exploring the additive bio-agent impacts upon ectoine production by Halomonas salina DSM5928T using corn steep liquor and soybean hydrolysate as nutrient supplement

(2020) Po-Wei Chen et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Biosynthesis of functional polyhydroxyalkanoates by engineered Halomonas bluephagenesis

(2020) Lin-Ping Yu et al.   METABOLIC ENGINEERING

Engineering Halomonas bluephagenesis for L-Threonine production

(2020) Hetong Du et al.   METABOLIC ENGINEERING

Comprehensive study on Escherichia coli genomic expression: Does position really matter?

(2020) Anke R. Goormans et al.   METABOLIC ENGINEERING

Rational flux-tuning of Halomonas bluephagenesis for co-production of bioplastic PHB and ectoine

(2020) Hong Ma et al.   Nature Communications

Pyruvate-responsive genetic circuits for dynamic control of central metabolism

(2020) Xianhao Xu et al.   Nature Chemical Biology

Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media

(2020) Johan Björkeroth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic engineering of Corynebacterium glutamicum for high‐level ectoine production – design, combinatorial assembly and implementation of a transcriptionally balanced heterologous ectoine pathway

(2019) Gideon Gießelmann et al.   Biotechnology Journal

Next‐Generation Industrial Biotechnology‐Transforming the Current Industrial Biotechnology into Competitive Processes

(2019) Lin‐Ping Yu et al.   Biotechnology Journal

Chromosome engineering of the TCA cycle in Halomonas bluephagenesis for production of copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate (PHBV)

(2019) Yong Chen et al.   METABOLIC ENGINEERING

Synthetic Biology and Genome-Editing Tools for Improving PHA Metabolic Engineering

(2019) Xu Zhang et al.   TRENDS IN BIOTECHNOLOGY

Towards a fully automated algorithm driven platform for biosystems design

(2019) Mohammad HamediRad et al.   Nature Communications

Production and characterisation of a marine Halomonas surface-active exopolymer

(2019) Tony Gutierrez et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Stimulus response-based fine-tuning of polyhydroxyalkanoate pathway in Halomonas

(2019) Jianwen Ye et al.   METABOLIC ENGINEERING

Construction of Halomonas bluephagenesis capable of high cell density growth for efficient PHA production

(2018) Yilin Ren et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Development of a cost-effective production process for Halomonas levan

(2018) Burak Adnan Erkorkmaz et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Pilot Scale-up of Poly(3-hydroxybutyrate-co -4-hydroxybutyrate) Production by Halomonas bluephagenesis via Cell Growth Adapted Optimization Process

(2018) Jianwen Ye et al.   Biotechnology Journal

Next generation industrial biotechnology based on extremophilic bacteria

(2018) Guo-Qiang Chen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Halomonas smyrnensis as a cell factory for co-production of PHB and levan

(2018) Souha Tohme et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Engineering of Halomonas bluephagenesis for low cost production of poly(3-hydroxybutyrate- co -4-hydroxybutyrate) from glucose

(2018) Jianwen Ye et al.   METABOLIC ENGINEERING

Increasing oxygen availability for improving poly(3-hydroxybutyrate) production by Halomonas

(2018) Pengfei Ouyang et al.   METABOLIC ENGINEERING

CRISPR/Cas9 editing genome of extremophile Halomonas spp.

(2018) Qin Qin et al.   METABOLIC ENGINEERING

Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products

(2018) Judith Becker et al.   METABOLIC ENGINEERING

Promoter Engineering for Enhanced P(3HB-co-4HB) Production by Halomonas bluephagenesis

(2018) Rui SHEN et al.   ACS Synthetic Biology

Pilot Scale-up of Poly(3-hydroxybutyrate-co -4-hydroxybutyrate) Production by Halomonas bluephagenesis via Cell Growth Adapted Optimization Process

(2018) Jianwen Ye et al.   Biotechnology Journal

Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis

(2018) Tao Yu et al.   CELL

Engineering NADH/NAD+ ratio in Halomonas bluephagenesis for enhanced production of polyhydroxyalkanoates (PHA)

(2018) Chen Ling et al.   METABOLIC ENGINEERING

Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors

(2018) Adam J. Meyer et al.   Nature Chemical Biology

Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B12

(2018) Huan Fang et al.   Nature Communications

Novel T7-like expression systems used for Halomonas

(2017) Han Zhao et al.   METABOLIC ENGINEERING

Controlling cell volume for efficient PHB production by Halomonas

(2017) Xiao-Ran Jiang et al.   METABOLIC ENGINEERING

Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit

(2017) Apoorv Gupta et al.   NATURE BIOTECHNOLOGY

EngineeringHalomonasspp. as A Low-Cost Production Host for Production of Bio-surfactant Protein PhaP

(2016) Lu-Hong Lan et al.   Biotechnology Journal

Pathway construction and metabolic engineering for fermentative production of ectoine in Escherichia coli

(2016) Yike Ning et al.   METABOLIC ENGINEERING

Genetic circuit design automation

(2016) A. A. K. Nielsen et al.   SCIENCE

Fed-Batch Biomolecule Production by Bacillus subtilis : A State of the Art Review

(2016) Sibel ÿztürk et al.   TRENDS IN BIOTECHNOLOGY

Microbial Synthesis of 5-Aminolevulinic Acid and Its Coproduction with Polyhydroxybutyrate

(2016) Tian Li et al.   ACS Synthetic Biology

EngineeringHalomonasspp. as A Low-Cost Production Host for Production of Bio-surfactant Protein PhaP

(2016) Lu-Hong Lan et al.   Biotechnology Journal

Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions

(2016) Yoshikazu Kawata et al.   AMB Express

Diversity and industrial potential of hydrolase-producing halophilic/halotolerant eubacteria

(2016) Evodia Setati Mathabatha   AFRICAN JOURNAL OF BIOTECHNOLOGY

Pseudomonas putida—a versatile host for the production of natural products

(2015) Anita Loeschcke et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Halophiles, coming stars for industrial biotechnology

(2015) Jin Yin et al.   BIOTECHNOLOGY ADVANCES

Engineering of core promoter regions enables the construction of constitutive and inducible promoters in Halomonas sp.

(2015) Tingting Li et al.   Biotechnology Journal

Effective stimulating factors for microbial levan production by Halomonas smyrnensis AAD6T

(2015) Hande Kazak Sarilmiser et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Algorithmic co-optimization of genetic constructs and growth conditions: application to 6-ACA, a potential nylon-6 precursor

(2015) Hui Zhou et al.   NUCLEIC ACIDS RESEARCH

Engineering of core promoter regions enables the construction of constitutive and inducible promoters in Halomonas sp.

(2015) Tingting Li et al.   Biotechnology Journal

Regulation of arsenite oxidation by the phosphate two-component system PhoBR in Halomonas sp. HAL1

(2015) Fang Chen et al.   Frontiers in Microbiology

Genomic analysis reveals the biotechnological and industrial potential of levan producing halophilic extremophile, Halomonas smyrnensis AAD6T

(2015) Elif Diken et al.   SpringerPlus

A seawater-based open and continuous process for polyhydroxyalkanoates production by recombinant Halomonas campaniensis LS21 grown in mixed substrates

(2014) Haitao Yue et al.   Biotechnology for Biofuels

Engineering Halomonas TD01 for the low-cost production of polyhydroxyalkanoates

(2014) Dan Tan et al.   METABOLIC ENGINEERING

Development of Halomonas TD01 as a host for open production of chemicals

(2014) Xiao-Zhi Fu et al.   METABOLIC ENGINEERING

Metabolomics-based component profiling of Halomonas sp. KM-1 during different growth phases in poly(3-hydroxybutyrate) production

(2013) You-Xun Jin et al.   BIORESOURCE TECHNOLOGY

Ectoine production from lignocellulosic biomass-derived sugars by engineered Halomonas elongata

(2013) Kosuke Tanimura et al.   BIORESOURCE TECHNOLOGY

The stimulatory effect of mannitol on levan biosynthesis: Lessons from metabolic systems analysis ofHalomonas smyrnensisAAD6T

(2013) Ozlem Ates et al.   BIOTECHNOLOGY PROGRESS

Non-sterile process for biohydrogen and 1,3-propanediol production from raw glycerol

(2013) Anniina Kivistö et al.   INTERNATIONAL JOURNAL OF HYDROGEN ENERGY

Application of polyhydroxyalkanoate (PHA) synthesis regulatory protein PhaR as a bio-surfactant and bactericidal agent

(2013) Hong-Kun Ma et al.   JOURNAL OF BIOTECHNOLOGY

Biobased chemicals: the convergence of green chemistry with industrial biotechnology

(2013) Jim C. Philp et al.   TRENDS IN BIOTECHNOLOGY

Utilization of renewable agricultural residues for the production of extracellular halostable cellulase from newly isolated Halomonas sp. strain PS47

(2012) Pooja Shivanand et al.   ANNALS OF MICROBIOLOGY

Biotechnology for a more sustainable world

(2012) Eugenia J. Olguín et al.   BIOTECHNOLOGY ADVANCES

Draft Genome Sequence of Halomonas smyrnensis AAD6T

(2012) E. Sogutcu et al.   JOURNAL OF BACTERIOLOGY

Draft Genome Sequence of Halomonas sp. Strain KM-1, a Moderately Halophilic Bacterium That Produces the Bioplastic Poly(3-Hydroxybutyrate)

(2012) Y. Kawata et al.   JOURNAL OF BACTERIOLOGY

Ribozyme-based insulator parts buffer synthetic circuits from genetic context

(2012) Chunbo Lou et al.   NATURE BIOTECHNOLOGY

Unsterile and continuous production of polyhydroxybutyrate by Halomonas TD01

(2011) Dan Tan et al.   BIORESOURCE TECHNOLOGY

Advanced bacterial polyhydroxyalkanoates: Towards a versatile and sustainable platform for unnatural tailor-made polyesters

(2011) Si Jae Park et al.   BIOTECHNOLOGY ADVANCES

Draft Genome Sequence of Halomonas sp. Strain HAL1, a Moderately Halophilic Arsenite-Oxidizing Bacterium Isolated from Gold-Mine Soil

(2011) Y. Lin et al.   JOURNAL OF BACTERIOLOGY

Taxonomic characterization and metabolic analysis of the Halomonas sp. KM-1, a highly bioplastic poly(3-hydroxybutyrate)-producing bacterium

(2011) Yoshikazu Kawata et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Development of pyrF-based gene knockout systems for genome-wide manipulation of the archaea Haloferax mediterranei and Haloarcula hispanica

(2011) Hailong Liu et al.   Journal of Genetics and Genomics

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

(2011) Judith Becker et al.   METABOLIC ENGINEERING

Metabolic engineering is key to a sustainable chemical industry

(2011) Annabel C. Murphy   NATURAL PRODUCT REPORTS

Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

(2011) Harry Yim et al.   Nature Chemical Biology

Poly(3-hydroxybutyrate) Production by IsolatedHalomonassp. KM-1 Using Waste Glycerol

(2010) Yoshikazu KAWATA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Ectoines in cell stress protection: Uses and biotechnological production

(2010) José M. Pastor et al.   BIOTECHNOLOGY ADVANCES

A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581T

(2010) Karin Schwibbert et al.   ENVIRONMENTAL MICROBIOLOGY

Industrial and environmental applications of halophilic microorganisms

(2010) Aharon Oren   ENVIRONMENTAL TECHNOLOGY

A process for the production of ectoine and poly(3-hydroxybutyrate) by Halomonas boliviensis

(2009) Héctor Guzmán et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthesis and production of polyhydroxyalkanoates by halophiles: current potential and future prospects

(2009) Jorge Quillaguamán et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Stabilized gene duplication enables long-term selection-free heterologous pathway expression

(2009) Keith E J Tyo et al.   NATURE BIOTECHNOLOGY

Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol

(2008) Eric J Steen et al.   Microbial Cell Factories

Application of systems biology for bioprocess development

(2008) Jin Hwan Park et al.   TRENDS IN BIOTECHNOLOGY