Shenlian extract protects against ultrafine particulate matter‐aggravated myocardial ischemic injury by inhibiting inflammation response via the activation of NLRP3 inflammasomes

Shenlian Extract Against Myocardial Injury Induced by Ischemia Through the Regulation of NF-κB/IκB Signaling Axis

(2020) Yuan Guo et al.   Frontiers in Pharmacology

We all breathe the same air …. and we are all mortal

(2020) Mark R Miller et al.   CARDIOVASCULAR RESEARCH

Validation of PM2.5 model particle through physicochemical evaluation and atherosclerotic plaque formation in ApoE-/- mice

(2020) Jingbo Zhao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Ultrafine particles: unique physicochemical properties relevant to health and disease

(2020) Hyouk-Soo Kwon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing

(2020) Jose Zavala et al.   International Journal of Environmental Research and Public Health

Ambient PM2.5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation

(2020) Yikai Shou et al.   TOXICOLOGY LETTERS

Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E-/- mice

(2019) Xihao Du et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Source apportionment of fine particle water soluble organic nitrogen (WSON) and its association with the inflammatory potential of lung epithelial cells

(2019) Qingyang Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Residential exposure to urban traffic is associated with the poorer neurobehavioral health of Ecuadorian schoolchildren

(2019) Khalid M. Khan et al.   NEUROTOXICOLOGY

MicroRNAs as biomarkers of harmful environmental and occupational exposures: a systematic review

(2019) Michail Kotsyfakis et al.   BIOMARKERS

PM2.5 concentration in the ambient air is a risk factor for the development of high-risk coronary plaques

(2019) Seokhun Yang et al.   European Heart Journal-Cardiovascular Imaging

Resveratrol alleviates chronic “real-world” ambient particulate matter-induced lung inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice

(2019) Shibin Ding et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Microbiome composition of airborne particulate matter from livestock farms and their effect on innate immune receptors and cells

(2019) Dingyu Liu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Integrating Network Pharmacology and Pharmacological Evaluation for Deciphering the Action Mechanism of Herbal Formula Zuojin Pill in Suppressing Hepatocellular Carcinoma

(2019) Wei Guo et al.   Frontiers in Pharmacology

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)

(2018) Bendik C. Brinchmann et al.   Particle and Fibre Toxicology

Air pollution as a risk factor in health impact assessments of a travel mode shift towards cycling

(2018) Wasif Raza et al.   Global Health Action

ETCM: an encyclopaedia of traditional Chinese medicine

(2018) Hai-Yu Xu et al.   NUCLEIC ACIDS RESEARCH

A Network Pharmacology Analysis to Explore the Effect of Astragali Radix-Radix Angelica Sinensis on Traumatic Brain Injury

(2018) Genggeng Xie et al.   Biomed Research International

CARD9-mediated ambient PM 2.5 -induced pulmonary injury is associated with Th17 cell

(2017) Shuo Jiang et al.   TOXICOLOGY LETTERS

Air particulate matter induced oxidative stress and inflammation in cardiovascular disease and atherosclerosis: The role of Nrf2 and AhR-mediated pathways

(2017) Akeem O. Lawal   TOXICOLOGY LETTERS

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Effects of Shenlian extract on experimental atherosclerosis in ApoE-deficient mice based on ultrasound biomicroscopy

(2016) Yan Guo et al.   BMC Complementary and Alternative Medicine

Exposure to Fine Particulate Air Pollution Is Associated With Endothelial Injury and Systemic InflammationNovelty and Significance

(2016) C. Arden Pope et al.   CIRCULATION RESEARCH

The health effects of ambient PM2.5 and potential mechanisms

(2016) Shaolong Feng et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia–reperfusion in the mouse

(2016) Stefano Toldo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

NLRX1 attenuates apoptosis and inflammatory responses in myocardial ischemia by inhibiting MAVS-dependent NLRP3 inflammasome activation

(2016) Hongyan Li et al.   MOLECULAR IMMUNOLOGY

Eyes on systems pharmacology

(2016) Yu Chen et al.   PHARMACOLOGICAL RESEARCH

Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation

(2016) Jaana Hartiala et al.   Journal of the American Heart Association

Targeting danger-associated molecular patterns after myocardial infarction

(2015) Gerardus PJ van Hout et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

IKK inhibition prevents PM2.5-exacerbated cardiac injury in mice with type 2 diabetes

(2015) Jinzhuo Zhao et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

PM2.5 and Cardiovascular Diseases in the Elderly: An Overview

(2015) Chenchen Wang et al.   International Journal of Environmental Research and Public Health

TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

(2014) Yi Liu et al.   BASIC RESEARCH IN CARDIOLOGY

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

CD36-Dependent 7-Ketocholesterol Accumulation in Macrophages Mediates Progression of Atherosclerosis in Response to Chronic Air Pollution Exposure

(2014) Xiaoquan Rao et al.   CIRCULATION RESEARCH

Source-specific fine particulate air pollution and systemic inflammation in ischaemic heart disease patients

(2014) Taina Siponen et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Endotoxin in concentrated coarse and fine ambient particles induces acute systemic inflammation in controlled human exposures

(2013) Behrooz Behbod et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

GROWTH AND DEVELOPMENT SYMPOSIUM: Endotoxin, inflammation, and intestinal function in livestock1,2

(2012) V. Mani et al.   JOURNAL OF ANIMAL SCIENCE

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

Subchronic effects of nasally instilled diesel exhaust particulates on the nasal and airway epithelia in mice

(2010) K. Yoshizaki et al.   INHALATION TOXICOLOGY

Antioxidant airway responses following experimental exposure to wood smoke in man

(2010) Maria Sehlstedt et al.   Particle and Fibre Toxicology

A Systematic Review of Occupational Exposure to Particulate Matter and Cardiovascular Disease

(2010) Shona C. Fang et al.   International Journal of Environmental Research and Public Health

Role of Paris PM2.5 components in the pro-inflammatory response induced in airway epithelial cells

(2009) Augustin Baulig et al.   TOXICOLOGY