Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer

Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment

(2013) Aamir Ahmad et al.   Anti-Cancer Agents in Medicinal Chemistry

Dolastatin, along with Celecoxib, stimulates apoptosis by a mechanism involving oxidative stress, membrane potential change and PI3-K/AKT pathway down regulation

(2013) Honit Piplani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Akt signaling pathway

(2012) SubbaRao V. Madhunapantula et al.   CANCER BIOLOGY & THERAPY

Angiostatic Properties of Sulindac and Celecoxib in the Experimentally Induced Inflammatory Colorectal Cancer

(2012) Vivek Vaish et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Role of cytokines and Jak3/Stat3 signaling in the 1,2-dimethylhydrazine dihydrochloride-induced rat model of colon carcinogenesis

(2012) Manpreet Kaur Saini et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species

(2012) H. Miki et al.   JOURNAL OF BIOCHEMISTRY

Up-regulation of p53 and mitochondrial signaling pathway in apoptosis by a combination of cox-2 inhibitor, celecoxib and dolastatin 15, a marine mollusk linear peptide in experimental colon carcinogenesis

(2012) Honit Piplani et al.   MOLECULAR CARCINOGENESIS

Targeting PDK1 in Cancer

(2011) C. Raimondi et al.   CURRENT MEDICINAL CHEMISTRY

In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-κB translocation

(2011) Siddig Ibrahim Abdelwahab et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo

(2011) MaLing Gou et al.   Nanoscale

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-carcinogenic properties of curcumin on colorectal cancer

(2010) Jung Park   World Journal of Gastrointestinal Oncology

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

(2008) Bharat B. Aggarwal et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

(2008) J. I. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

(2008) Laura Piccagli et al.   BMC STRUCTURAL BIOLOGY

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY