Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor
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Title
Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor
Authors
Keywords
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Journal
EMBO JOURNAL
Volume -, Issue -, Pages -
Publisher
EMBO
Online
2021-05-01
DOI
10.15252/embj.2020107226
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Note: Only part of the references are listed.- Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle
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- Biomolecular condensates in cell biology and virology: Phase-separated membraneless organelles (MLOs)
- (2020) Pravin B. Sehgal et al. ANALYTICAL BIOCHEMISTRY
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- (2020) Nicholas A. Smith et al. PROTEIN SCIENCE
- A Plasmodium cysteine protease required for efficient transition from the liver infection stage
- (2020) Elyzana Dewi Putrianti et al. PLoS Pathogens
- PfMSA180 is a novel Plasmodium falciparum vaccine antigen that interacts with human erythrocyte integrin associated protein (CD47)
- (2019) Hikaru Nagaoka et al. Scientific Reports
- Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
- (2019) Franziska Mohring et al. eLife
- The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress
- (2018) Abigail J. Perrin et al. mBio
- A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells
- (2018) James A. Thomas et al. Nature Microbiology
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- Peptidomimetic plasmepsin inhibitors with potent anti-malarial activity and selectivity against cathepsin D
- (2018) Rimants Zogota et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Identification of a novel merozoite surface antigen of Plasmodium vivax, PvMSA180
- (2017) Fauzi Muh et al. MALARIA JOURNAL
- Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
- (2017) Armiyaw S. Nasamu et al. SCIENCE
- A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress
- (2017) Paco Pino et al. SCIENCE
- A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission
- (2017) David A. Baker et al. Nature Communications
- Generating conditional gene knockouts in Plasmodium – a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9
- (2017) Ellen Knuepfer et al. Scientific Reports
- The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes
- (2017) Christine R. Collins et al. PLoS Pathogens
- A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum
- (2016) Matthew L. Jones et al. Scientific Reports
- Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets
- (2016) Sonia Verma et al. Frontiers in Pharmacology
- Development and Application of a Simple Plaque Assay for the Human Malaria Parasite Plasmodium falciparum
- (2016) James A. Thomas et al. PLoS One
- Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle
- (2015) Robert Stallmach et al. MOLECULAR MICROBIOLOGY
- Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors
- (2015) Simone Giovani et al. RSC Advances
- Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1
- (2014) Samir S. Kher et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Robust inducible Cre recombinase activity in the human malaria parasitePlasmodium falciparumenables efficient gene deletion within a single asexual erythrocytic growth cycle
- (2013) Christine R. Collins et al. MOLECULAR MICROBIOLOGY
- Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress
- (2013) Christine R. Collins et al. PLoS Pathogens
- Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target
- (2012) Chrislaine Withers-Martinez et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Proteolytic Activation of the Essential Parasitophorous Vacuole Cysteine Protease SERA6 Accompanies Malaria Parasite Egress from Its Host Erythrocyte
- (2012) Andrea Ruecker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Adaptation of the genetically tractable malaria pathogen Plasmodium knowlesi to continuous culture in human erythrocytes
- (2012) R. W. Moon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cysteine cathepsins: From structure, function and regulation to new frontiers
- (2011) Vito Turk et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Global Identification of Multiple Substrates forPlasmodium falciparumSUB1, an Essential Malarial Processing Protease
- (2011) Natalie C. Silmon de Monerri et al. INFECTION AND IMMUNITY
- Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species
- (2011) Nobuko Arisue et al. PLoS One
- Biophysics of Malarial Parasite Exit from Infected Erythrocytes
- (2011) Rajesh Chandramohanadas et al. PLoS One
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- (2010) Svetlana Glushakova et al. CURRENT BIOLOGY
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- (2010) Bryan T. Mott et al. JOURNAL OF MEDICINAL CHEMISTRY
- A multifunctional serine protease primes the malaria parasite for red blood cell invasion
- (2009) Konstantinos Koussis et al. EMBO JOURNAL
- An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery
- (2009) Christine R. Collins et al. PLoS Pathogens
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