Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo

AdipoRon , a new therapeutic prospect for Duchenne muscular dystrophy

(2020) Michel Abou‐Samra et al.   Journal of Cachexia Sarcopenia and Muscle

Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy

(2020) Sandra Rayego-Mateos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Renal expression of cytokines and chemokines in diabetic nephropathy

(2020) Liliane Silvano Araújo et al.   BMC Nephrology

Potential Adiponectin Receptor Response Modifier Therapeutics

(2019) Laszlo Otvos   Frontiers in Endocrinology

Pro-inflammatory cytokines are associated with podocyte damage and proximal tubular dysfunction in the early stage of diabetic kidney disease in type 2 diabetes mellitus patients

(2019) Oana Milas et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

AdipoRon Alleviates Free Fatty Acid-Induced Myocardial Cell Injury Via Suppressing Nlrp3 Inflammasome Activation

(2019) You-Zhi Zhang et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

The Adiponectin Receptor Agonist AdipoRon Ameliorates Diabetic Nephropathy in a Model of Type 2 Diabetes

(2018) Yaeni Kim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice

(2018) Rui Wu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury

(2018) Qishuang Zhou et al.   JOURNAL OF NEUROTRAUMA

Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression

(2018) Sarah Nicolas et al.   Translational Psychiatry

The Gut-Kidney Axis: Putative Interconnections Between Gastrointestinal and Renal Disorders

(2018) Markku Lehto et al.   Frontiers in Endocrinology

Adiponectin and Its Receptors in Diabetic Kidney Disease: Molecular Mechanisms and Clinical Potential

(2017) Dongqing Zha et al.   ENDOCRINOLOGY

Adiponectin confers protection from acute colitis and restricts a B cell immune response

(2017) Stephanie Obeid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice

(2017) Huaiguo Wang et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria

(2017) Ming-Fo Hsu et al.   Scientific Reports

Overexpression of transcription factor FOXC2 in cultured human podocytes upregulates injury markers and increases motility

(2016) Neeta Datta et al.   EXPERIMENTAL CELL RESEARCH

Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis

(2016) Vivette D. D'Agati et al.   Nature Reviews Nephrology

Deletion of the gene for adiponectin accelerates diabetic nephropathy in the Ins2 +/C96Y mouse

(2015) Fei Fang et al.   DIABETOLOGIA

Methods to determine intestinal permeability and bacterial translocation during liver disease

(2015) Lirui Wang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury

(2015) Alaa S. Awad et al.   KIDNEY INTERNATIONAL

Inverse Levels of Adiponectin in Type 1 and Type 2 Diabetes Are in Accordance with the State of Albuminuria

(2015) Spomenka Ljubic et al.   International Journal of Endocrinology

Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway

(2015) P Saurus et al.   Cell Death & Disease

Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy

(2015) Mervi E. Hyvönen et al.   Biomed Research International

Enhanced glomerular Toll-like receptor 4 expression and signaling in patients with type 2 diabetic nephropathy and microalbuminuria

(2014) Daniela Verzola et al.   KIDNEY INTERNATIONAL

Intraperitoneal administration of the globular adiponectin gene ameliorates diabetic nephropathy in Wistar rats

(2014) FANG YUAN et al.   Molecular Medicine Reports

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

(2013) Miki Okada-Iwabu et al.   NATURE

The effect of bariatric surgery on renal function and disease: a focus on outcomes and inflammation

(2013) K. J. Neff et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Intestinal alkaline phosphatase prevents metabolic syndrome in mice

(2013) K. Kaliannan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation in Diabetic Nephropathy

(2012) Andy K. H. Lim et al.   MEDIATORS OF INFLAMMATION

Plasma adiponectin is related to the progression of kidney disease in type 2 diabetes patients

(2012) Ina Maria Kacso et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Propensity to high-fat diet-induced obesity in rats is associated with changes in the gut microbiota and gut inflammation

(2010) Claire Barbier de La Serre et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Serum Lipopolysaccharide Activity Is Associated With the Progression of Kidney Disease in Finnish Patients With Type 1 Diabetes

(2009) M. Nymark et al.   DIABETES CARE

Adiponectin regulates albuminuria and podocyte function in mice

(2008) Kumar Sharma et al.   JOURNAL OF CLINICAL INVESTIGATION

New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy

(2008) Frank C. Brosius   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS