Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration

Hyperoxia Injury in the Developing Lung is Mediated by Mesenchymal Expression of Wnt5A

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Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adults

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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

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COVID-19 pneumonia: different respiratory treatments for different phenotypes?

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STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury

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Early lineage specification defines alveolar epithelial ontogeny in the murine lung

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Yap/Taz regulate alveolar regeneration and resolution of lung inflammation

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(2019) Jarod A. Zepp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1

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Ager-CreERT2: A New Genetic Tool for Studying Lung Alveolar Development, Homeostasis, and Repair

(2018) Mei-I Chung et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Strength of Mechanical Forces Determines the Differentiation of Alveolar Epithelial Cells

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Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells

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Expression of mutant Sftpc in murine alveolar epithelia drives spontaneous lung fibrosis

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Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

(2018) William J. Zacharias et al.   NATURE

Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing

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(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

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chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

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Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development

(2016) Shanru Li et al.   DEVELOPMENTAL BIOLOGY

HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation

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(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

(2016) Masato Morikawa et al.   Cold Spring Harbor Perspectives in Biology

Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation

(2016) David B. Frank et al.   Cell Reports

Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair

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High-Efficiency Type II Cell–Enhanced Green Fluorescent Protein Expression Facilitates Cellular Identification, Tracking, and Isolation

(2015) Jeff N. Vanderbilt et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The development and plasticity of alveolar type 1 cells

(2015) Jun Yang et al.   DEVELOPMENT

FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung Branching

(2015) John C. Herriges et al.   DEVELOPMENTAL CELL

Altered lung function at mid-adulthood in mice following neonatal exposure to hyperoxia

(2015) Foula Sozo et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung

(2015) Rajan Jain et al.   Nature Communications

Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function

(2014) Brigid L.M. Hogan et al.   Cell Stem Cell

The Hippo Pathway Effector Yap Controls Patterning and Differentiation of Airway Epithelial Progenitors

(2014) John E. Mahoney et al.   DEVELOPMENTAL CELL

Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice

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Neonatal Hyperoxia Stimulates the Expansion of Alveolar Epithelial Type II Cells

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Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

(2013) Tao Gao et al.   GASTROENTEROLOGY

Type 2 alveolar cells are stem cells in adult lung

(2013) Christina E. Barkauskas et al.   JOURNAL OF CLINICAL INVESTIGATION

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis

(2013) C. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development

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Lung development and the host response to influenza A virus are altered by different doses of neonatal oxygen in mice

(2012) Bradley W. Buczynski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

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(2012) Alexander Dobin et al.   BIOINFORMATICS

Genome-scale study of transcription factor expression in the branching mouse lung

(2012) John C. Herriges et al.   DEVELOPMENTAL DYNAMICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice

(2011) Harold A. Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Interconversion Between Intestinal Stem Cell Populations in Distinct Niches

(2011) N. Takeda et al.   SCIENCE

Alveolar Surfactant Homeostasis and the Pathogenesis of Pulmonary Disease

(2010) Jeffrey A. Whitsett et al.   Annual Review of Medicine

The Migration of T Cells in Response to Influenza Virus Is Altered in Neonatal Mice

(2010) J. L. Lines et al.   JOURNAL OF IMMUNOLOGY

Neonatal oxygen adversely affects lung function in adult mice without altering surfactant composition or activity

(2009) Min Yee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Wnt2/2b and β-Catenin Signaling Are Necessary and Sufficient to Specify Lung Progenitors in the Foregut

(2009) Ashley M. Goss et al.   DEVELOPMENTAL CELL