Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1

Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1

(2019) Danielle R. Little et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Mouse Cell Atlas by Microwell-Seq

(2018) Xiaoping Han et al.   CELL

β-Catenin maintains lung epithelial progenitors after lung specification

(2018) Edwin J. Ostrin et al.   DEVELOPMENT

The Strength of Mechanical Forces Determines the Differentiation of Alveolar Epithelial Cells

(2018) Jiao Li et al.   DEVELOPMENTAL CELL

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

(2018) Purushothama Rao Tata et al.   DEVELOPMENTAL CELL

Pulmonary alveolar type I cell population consists of two distinct subtypes that differ in cell fate

(2018) Yanjie Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing

(2018) Leah B. Nantie et al.   DEVELOPMENT

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

(2018) Gurkan Mollaoglu et al.   IMMUNITY

FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer

(2018) Soledad A Camolotto et al.   eLife

The NANCI–Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis

(2017) Michael J. Herriges et al.   GENES & DEVELOPMENT

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq

(2017) Lihe Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory

(2017) Lorenza Magno et al.   Cell Reports

Implications of Schwann Cells Biomechanics and Mechanosensitivity for Peripheral Nervous System Physiology and Pathophysiology

(2017) Gonzalo Rosso et al.   Frontiers in Molecular Neuroscience

Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development

(2017) Shilpi Minocha et al.   Scientific Reports

Combinations of differentiation markers distinguish subpopulations of alveolar epithelial cells in adult lung

(2016) Janice M. Liebler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epithelial membrane protein 2 regulates sphingosylphosphorylcholine-induced keratin 8 phosphorylation and reorganization: Changes of PP2A expression by interaction with alpha4 and caveolin-1 in lung cancer cells

(2016) Eun Ji Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Type IV collagen drives alveolar epithelial–endothelial association and the morphogenetic movements of septation

(2016) Maria Loscertales et al.   BMC BIOLOGY

Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung

(2016) Xiaoru Wang et al.   DEVELOPMENTAL BIOLOGY

HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation

(2016) Yi Wang et al.   DEVELOPMENTAL CELL

Tead1 regulates the expression ofPeripheral Myelin Protein 22during Schwann cell development

(2016) Camila Lopez-Anido et al.   HUMAN MOLECULAR GENETICS

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons

(2016) Magnus Sandberg et al.   NEURON

Emergence of a Wave of Wnt Signaling that Regulates Lung Alveologenesis by Controlling Epithelial Self-Renewal and Differentiation

(2016) David B. Frank et al.   Cell Reports

On the Tricks Alveolar Epithelial Cells Play to Make a Good Lung

(2015) Ewald R. Weibel   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The development and plasticity of alveolar type 1 cells

(2015) Jun Yang et al.   DEVELOPMENT

A conserved MST1/2–YAP axis mediates Hippo signaling during lung growth

(2015) Chuwen Lin et al.   DEVELOPMENTAL BIOLOGY

Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

(2015) Carman Man-Chung Li et al.   GENES & DEVELOPMENT

Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain

(2015) Alisa Mo et al.   NEURON

Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung

(2015) Rajan Jain et al.   Nature Communications

Alveolar progenitor and stem cells in lung development, renewal and cancer

(2014) Tushar J. Desai et al.   NATURE

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung

(2014) Alexander W. Lange et al.   Journal of Molecular Cell Biology

Developmental programs of lung epithelial progenitors: a balanced progenitor model

(2014) Jun Yang et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Nkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma

(2013) Eric L. Snyder et al.   MOLECULAR CELL

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

(2012) S. G. Landt et al.   GENOME RESEARCH

KrasG12D and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung

(2012) Yutaka Maeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-Wide Analyses of Nkx2-1 Binding to Transcriptional Target Genes Uncover Novel Regulatory Patterns Conserved in Lung Development and Tumors

(2012) Jean-Bosco Tagne et al.   PLoS One

In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1

(2011) Daniel Silberschmidt et al.   BMC DEVELOPMENTAL BIOLOGY

The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1

(2011) Lorenza Magno et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

(2011) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development

(2010) Edward E. Morrisey et al.   DEVELOPMENTAL CELL

Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons

(2010) Tsunemitsu Soeda et al.   GENESIS

Mutations in AKAP5 Disrupt Dendritic Signaling Complexes and Lead to Electrophysiological and Behavioral Phenotypes in Mice

(2010) Michael Weisenhaus et al.   PLoS One

Directed Expression of Cre in Alveolar Epithelial Type 1 Cells

(2009) Per Flodby et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Arcuate nucleus expression of NKX2.1 and DLX and lineages expressing these transcription factors in neuropeptide Y+, proopiomelanocortin+, and tyrosine hydroxylase+neurons in neonatal and adult mice

(2009) Cindy L. Yee et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

(2008) Myriam Heiman et al.   CELL